Ranked list
The 10 largest hospitals in Iowa by net patient revenue
The same ranking for Iowa hospitals.
Avera McKennan Hospital & University Health Center has the most net patient revenue of any hospital in South Dakota, $1.71 billion, followed by Sanford USD Medical Center in Sioux Falls ($1.44B) and Monument Health Rapid City Hospital in Rapid City ($830.1M). Together the 10 leaders account for $5.08 billion in net patient revenue in seven cities.
The 10 highest of 58 South Dakota hospitals that report net patient revenue. Ranks compare size, not quality of care.
Every hospital in South Dakota58 South Dakota hospitals report net patient revenue, $6.45 billion in all. The 10 on this list hold $5.08 billion of it. The median hospital has $20.5 million in net patient revenue, so Avera McKennan Hospital & University Health Center is about 83 times that size.
FAQ
Answers from the same data, updated monthly.
Avera McKennan Hospital & University Health Center in Sioux Falls, with $1.71 billion in net patient revenue. Sanford USD Medical Center is second with $1.44B.
Avera McKennan Hospital & University Health Center ($1.71B), Sanford USD Medical Center ($1.44B), Monument Health Rapid City Hospital ($830.1M), Avera St. Luke's Hospital ($198.1M), Avera Heart Hospital ($194.5M), Sanford Health Watertown ($162.4M), Sioux Falls Specialty Hospital ($154.7M), Avera Sacred Heart Hospital ($138M), Avera Queen of Peace Hospital ($126.5M), Avera St. Mary's Hospital ($124.6M).
The median South Dakota hospital that reports net patient revenue has $20.5 million in net patient revenue, out of 58 that report them.
Every month, when the Dmand AI database refreshes. This version is from Oct 28, 2026.
Ranked list
The same ranking for Iowa hospitals.
Ranked list
The national ranking by net patient revenue.
Insight
MEDITECH runs 40% of South Dakota hospitals with an EHR on file.
Dmand AI
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