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The 10 busiest hospitals in South Carolina by inpatient discharges

MUSC Health University Medical Center has the most inpatient discharges of any hospital in South Carolina, 44,220, followed by Prisma Health Greenville Memorial Hospital in Greenville (38,312) and Spartanburg Medical Center in Spartanburg (31,610). Together the 10 leaders hold 292,766 discharges in eight cities.

Updated Inpatient discharges from each hospital's latest Medicare cost reportHow we ranked

Rank by
Location
South Carolina
  1. MUSC Health University Medical CenterCharleston · Medical University of South Carolina44,220discharges949beds
  2. Prisma Health Greenville Memorial HospitalGreenville · Prisma Health38,312discharges735beds
  3. Spartanburg Medical CenterSpartanburg · Spartanburg Regional Healthcare System31,610discharges686beds
  4. Lexington Medical CenterWest Columbia · Lexington Health31,563discharges547beds
  5. McLeod Regional Medical Center FlorenceFlorence · McLeod Health27,520discharges524beds
  6. Prisma Health Richland HospitalColumbia · Prisma Health26,145discharges606beds
  7. HCA Healthcare Trident HospitalCharleston · HCA Healthcare25,149discharges395beds
  8. Grand Strand Medical CenterMyrtle Beach · HCA Healthcare24,509discharges355beds
  9. AnMed Medical CenterAnderson · AnMed22,142discharges348beds
  10. Bon Secours St. Francis DowntownGreenville · Bon Secours Mercy Health21,596discharges374beds

The 10 highest of 81 South Carolina hospitals that report inpatient discharges. Ranks compare size, not quality of care.

Every hospital in South Carolina

The 10 top South Carolina hospitals hold 53% of all inpatient discharges

81 South Carolina hospitals report inpatient discharges, 552,243 inpatient discharges in all. The 10 on this list hold 292,766 of it. The median hospital has 3,047 discharges, so MUSC Health University Medical Center is about 15 times that size.

of all inpatient discharges at South Carolina hospitals that report them
53%
the size of the median South Carolina hospital, which has 3,047 discharges
15×
of the 81 South Carolina hospitals that report inpatient discharges
12%

How we ranked the top South Carolina hospitals

Measure
Inpatient discharges from each hospital's latest Medicare cost report.
What counts as a hospital
One CMS certification number. A hospital with several campuses under one number counts once.
Field
81 South Carolina hospitals in the Dmand AI database report inpatient discharges.
Ties
Hospitals with the same number share a rank.
What a rank means
Size only. A rank compares inpatient discharges; it says nothing about quality of care.
Refresh
Monthly. Updated Oct 28, 2026.

FAQ

Questions about the top South Carolina hospitals

Answers from the same data, updated monthly.

What is the busiest hospital in South Carolina?

MUSC Health University Medical Center in Charleston, with 44,220 discharges. Prisma Health Greenville Memorial Hospital is second with 38,312.

What are the top 10 South Carolina hospitals by inpatient discharges?

MUSC Health University Medical Center (44,220), Prisma Health Greenville Memorial Hospital (38,312), Spartanburg Medical Center (31,610), Lexington Medical Center (31,563), McLeod Regional Medical Center Florence (27,520), Prisma Health Richland Hospital (26,145), HCA Healthcare Trident Hospital (25,149), Grand Strand Medical Center (24,509), AnMed Medical Center (22,142), Bon Secours St. Francis Downtown (21,596).

How many inpatient discharges does a typical South Carolina hospital have?

The median South Carolina hospital that reports inpatient discharges has 3,047 discharges, out of 81 that report them.

How often is this list updated?

Every month, when the Dmand AI database refreshes. This version is from Oct 28, 2026.

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    The same ranking for Georgia hospitals.

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    The national ranking by inpatient discharges.

  • Insight

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    Epic runs 48% of South Carolina hospitals with an EHR on file.

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