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The 10 largest hospitals in Missouri by employees

Barnes-Jewish Hospital has the most employees of any hospital in Missouri, 10,215, followed by Cox Medical Center South in Springfield (7,862) and University Hospital in Columbia (7,265). Together the 10 leaders hold 52,537 employees in six cities.

Updated Full-time equivalent employees from each hospital's latest Medicare cost reportHow we ranked

Rank by
Location
Missouri
  1. Barnes-Jewish HospitalSaint Louis · BJC HealthCare10,215employees1,329beds
  2. Cox Medical Center SouthSpringfield · Lester E. Cox Medical Centers7,862employees771beds
  3. University HospitalColumbia · University of Missouri System7,265employees657beds
  4. Mercy Hospital St. LouisSaint Louis · Mercy5,074employees782beds
  5. Children's Mercy Adele HallKansas City · Children's Mercy Hospital4,395employees329beds
  6. Mercy Hospital SpringfieldSpringfield · Mercy4,196employees621beds
  7. St. Louis Children's HospitalSaint Louis · BJC HealthCare3,656employees467beds
  8. Saint Luke's Hospital of Kansas CityKansas City · BJC HealthCare3,516employees452beds
  9. Saint Francis Medical CenterCape Girardeau · Saint Francis Healthcare System3,378employees282beds
  10. Freeman Hospital WestJoplin · Freeman Health System2,980employees347beds

The 10 highest of 128 Missouri hospitals that report employees. Ranks compare size, not quality of care.

Every hospital in Missouri

The 10 top Missouri hospitals hold 45% of all employees

128 Missouri hospitals report employees, 116,226 employees in all. The 10 on this list hold 52,537 of it. The median hospital has 278 employees, so Barnes-Jewish Hospital is about 37 times that size.

of all employees at Missouri hospitals that report them
45%
the size of the median Missouri hospital, which has 278 employees
37×
of the 128 Missouri hospitals that report employees
7.8%

How we ranked the top Missouri hospitals

Measure
Full-time equivalent employees from each hospital's latest Medicare cost report.
What counts as a hospital
One CMS certification number. A hospital with several campuses under one number counts once.
Field
128 Missouri hospitals in the Dmand AI database report employees.
Ties
Hospitals with the same number share a rank.
What a rank means
Size only. A rank compares employees; it says nothing about quality of care.
Refresh
Monthly. Updated Oct 28, 2026.

FAQ

Questions about the top Missouri hospitals

Answers from the same data, updated monthly.

Which Missouri hospital has the most employees?

Barnes-Jewish Hospital in Saint Louis, with 10,215 employees. Cox Medical Center South is second with 7,862.

What are the top 10 Missouri hospitals by employees?

Barnes-Jewish Hospital (10,215), Cox Medical Center South (7,862), University Hospital (7,265), Mercy Hospital St. Louis (5,074), Children's Mercy Adele Hall (4,395), Mercy Hospital Springfield (4,196), St. Louis Children's Hospital (3,656), Saint Luke's Hospital of Kansas City (3,516), Saint Francis Medical Center (3,378), Freeman Hospital West (2,980).

How many employees does a typical Missouri hospital have?

The median Missouri hospital that reports employees has 278 employees, out of 128 that report them.

How often is this list updated?

Every month, when the Dmand AI database refreshes. This version is from Oct 28, 2026.

More ranked lists

Every ranked list

  • Ranked list

    The 10 largest hospitals in Arkansas by employees

    The same ranking for Arkansas hospitals.

  • Ranked list

    The 10 largest hospitals in the US by employees

    The national ranking by employees.

  • Insight

    EHR market share in Missouri

    Epic runs 38% of Missouri hospitals with an EHR on file.

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