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The 10 largest hospitals in Missouri by staffed beds

Barnes-Jewish Hospital is the largest hospital in Missouri, with 1,329 staffed beds, followed by Mercy Hospital St. Louis in Saint Louis (782) and Cox Medical Center South in Springfield (771). Together the 10 largest hold 6,790 staffed beds in five cities.

Updated Staffed beds from each hospital's latest Medicare cost reportHow we ranked

Rank by
Location
Missouri
  1. Barnes-Jewish HospitalSaint Louis · BJC HealthCare1,329beds3,519HCPs
  2. Mercy Hospital St. LouisSaint Louis · Mercy782beds2,765HCPs
  3. Cox Medical Center SouthSpringfield · Lester E. Cox Medical Centers771beds1,342HCPs
  4. Mercy Hospital SouthSaint Louis · Mercy748beds1,497HCPs
  5. University HospitalColumbia · University of Missouri System657beds1,731HCPs
  6. Mercy Hospital SpringfieldSpringfield · Mercy621beds1,396HCPs
  7. SSM Health St. Mary's Hospital - St. LouisSaint Louis · SSM Health Care488beds989HCPs
  8. St. Louis Children's HospitalSaint Louis · BJC HealthCare467beds921HCPs
  9. Fulton State HospitalFulton · State of Missouri464beds29HCPs
  10. SSM Health DePaul Hospital - St. LouisBridgeton · SSM Health Care463beds750HCPs

The 10 largest of 127 Missouri hospitals that report staffed beds. Ranks compare size, not quality of care.

Every hospital in Missouri

The 10 largest Missouri hospitals hold 35% of all staffed beds

127 Missouri hospitals report staffed beds, 19,192 staffed beds in all. The 10 on this list hold 6,790 of it. The median hospital has 62 staffed beds, so Barnes-Jewish Hospital is about 21 times that size.

of all staffed beds at Missouri hospitals that report them
35%
the size of the median Missouri hospital, which has 62 staffed beds
21×
of the 127 Missouri hospitals that report staffed beds
7.9%

635 executives and department leaders work at the 10 largest Missouri hospitals

Executive leadership is the largest leadership group, with 88, followed by operations and administration with 74. 13,071 HCPs have a current affiliation at these hospitals, 8,343 of them physicians; internal medicine is the largest physician specialty, with 1,003. Names, titles and contact details are in Dmand AI.

Executive leadership is the biggest leadership group

Executives and department leaders at the 10 largest Missouri hospitals, top 9 departments
  1. Executive leadership88
  2. Operations and administration74
  3. Service lines and programs38
  4. Physicians and medical leadership34
  5. Facilities and support services30
  6. Marketing and patient experience30
  7. Nursing leadership30
  8. Diagnostics29
  9. Human resources22

Source: Dmand AI executive data, Oct 28, 2026

13,071 HCPs have a current affiliation at the 10

HCPs at the 10 largest Missouri hospitals by type, each counted once
  1. Physicians (MD, DO)8,343
  2. Nurses and nurse practitioners2,999
  3. Physician assistants1,018
  4. Behavioral health clinicians286
  5. Other HCPs425

Source: Dmand AI affiliation data, Oct 28, 2026

How we ranked the largest Missouri hospitals

Measure
Staffed beds from each hospital's latest Medicare cost report.
What counts as a hospital
One CMS certification number. A hospital with several campuses under one number counts once.
Field
127 Missouri hospitals in the Dmand AI database report staffed beds.
Ties
Hospitals with the same number share a rank.
HCPs
Healthcare professionals with a current affiliation to the hospital in the Dmand AI database.
What a rank means
Size only. A rank compares staffed beds; it says nothing about quality of care.
Refresh
Monthly. Updated Oct 28, 2026.

FAQ

Questions about the largest Missouri hospitals

Answers from the same data, updated monthly.

What is the largest hospital in Missouri?

Barnes-Jewish Hospital in Saint Louis, with 1,329 staffed beds on its latest Medicare cost report. Mercy Hospital St. Louis is second with 782.

What are the 10 largest hospitals in Missouri?

By staffed beds: Barnes-Jewish Hospital (1,329), Mercy Hospital St. Louis (782), Cox Medical Center South (771), Mercy Hospital South (748), University Hospital (657), Mercy Hospital Springfield (621), SSM Health St. Mary's Hospital - St. Louis (488), St. Louis Children's Hospital (467), Fulton State Hospital (464), SSM Health DePaul Hospital - St. Louis (463).

How many staffed beds does a typical Missouri hospital have?

The median Missouri hospital that reports staffed beds has 62 staffed beds, out of 127 that report them.

Why do hospital bed counts differ between lists?

Lists count different beds. This one uses staffed beds: beds set up and staffed for patients during the cost report year, as each hospital reports them to Medicare. Licensed beds, the most a state allows, are usually higher, and some lists add up every campus or every hospital in a health system, so the same hospital can rank differently from one list to the next.

How often is this list updated?

Every month, when the Dmand AI database refreshes. This version is from Oct 28, 2026.

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