Largest primary care groups in South Carolina
- Groups
- 448
- Internal Medicine groups
- 177
- Nurse Practitioner groups
- 123
- Internal medicine specialists
- 2,361
- Nurse practitioner specialists
- 379
There are 448 primary care groups in South Carolina with a Medicare PAC ID: 177 internal medicine, 123 nurse practitioner, 122 family medicine and 25 physician assistant. Prisma Health Medical Group is the largest internal medicine group, with 369 internal medicine specialists, and CVS MinuteClinic the largest nurse practitioner group, with 99 nurse practitioner specialists.
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Prisma Health Medical Group is the largest primary care group in South Carolina, with 1,915 physicians
Ranked by physicians with a South Carolina address linked to each group. MUSC Health is second with 1,364, and MUSC Community Physicians third with 965. 22 South Carolina groups have 100 or more physicians.
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Showing 1 to 10 of 448 primary care groups in South Carolina
Sources: Doctors and Clinicians National Downloadable File (CMS) and Dmand AI Affiliation Data
Prisma Health Medical Group is the largest internal medicine group in South Carolina, with 369 internal medicine specialists
Ranked by internal medicine specialists with a South Carolina address linked to each group whose main sub-specialty is internal medicine. MUSC Health is second with 320, and Prisma Health Medical Group-Midlands third with 261.
Sources: Doctors and Clinicians National Downloadable File (CMS) and Dmand AI Affiliation Data
CVS MinuteClinic is the largest nurse practitioner group in South Carolina, with 99 nurse practitioner specialists
Ranked by nurse practitioner specialists with a South Carolina address linked to each group whose main sub-specialty is nurse practitioner. Empatia Palliative Care is second with 18, and Palmetto Internal Medicine & Primary Care third with 11.
Sources: Doctors and Clinicians National Downloadable File (CMS) and Dmand AI Affiliation Data
AnMed is the largest family medicine group in South Carolina, with 108 family physicians
Ranked by family physicians with a South Carolina address linked to each group whose main sub-specialty is family medicine. Self Medical Group is second with 89, and Montgomery Center Family Medicine third with 74.
Sources: Doctors and Clinicians National Downloadable File (CMS) and Dmand AI Affiliation Data
NasonCare is the largest physician assistant group in South Carolina, with 5 physician assistant specialists
Ranked by physician assistant specialists with a South Carolina address linked to each group whose main sub-specialty is physician assistant. East Cooper Plastic Surgery is second with 3, and Coastal Dermatology Institute third with 3.
Sources: Doctors and Clinicians National Downloadable File (CMS) and Dmand AI Affiliation Data
Prisma Health has the most physicians in South Carolina primary care groups, with 2,811 across 5 groups
Dmand AI maps every medical group to its parent organization, up to the health system or platform at the top. 21 parent organizations have two or more South Carolina primary care groups. Among health systems, Medical University of South Carolina has the most groups, 14. Each clinician counts once per parent organization.
See every medical group, site and clinician under Prisma Health
Org Hierarchy Explorer maps every group, site of care and clinician under the parent, with the leaders at each group.
Source: Dmand AI Org Hierarchy Data
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Dmand AI maps the owners, administrators and physician leaders at each of the 448 South Carolina primary care groups, with the parent organization above each one, and finds validated work emails and mobile numbers.
62% of South Carolina primary care groups are independent, with no larger parent organization
A group counts as independent when no health system, platform or other organization sits above it in the org hierarchy. Every other group belongs to a larger organization.
South Carolina primary care groups by ownership
- Independent276
- Health system or hospital74
- Platform or corporate owner28
- Community or government19
- Other organization51
Sites of care beyond their own offices
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Dmand AI maps each group to the health system, physician platform or management company above it, so you can sell to the owner, not one site.
Source: Dmand AI Org Hierarchy Data
71 South Carolina primary care groups practice at a hospital site, and 36 at a rural health clinic
Sites of care linked to each group in the org hierarchy, beyond its own offices. A group can practice at several kinds of site.
South Carolina primary care groups by site of care
- Hospitals71
- Rural health clinics36
- FQHCs32
- Skilled nursing facilities17
- Hospices12
- Ambulatory surgery centers11
- Therapy and rehab centers7
- Behavioral health facilities7
- Dialysis centers5
- Home health agencies5
Clinicians in South Carolina primary care groups
Sources: Dmand AI Practice Data and Dmand AI Org Hierarchy Data
Greenville has the most primary care groups in South Carolina, with 37
More South Carolina cities with primary care groups
- Florence19
- Aiken14
- Spartanburg14
- Easley12
- North Charleston12
- Mount Pleasant11
- Sumter11
- Bluffton10
- Hilton Head Island10
- Orangeburg10
- Conway8
- Greenwood7
- Summerville7
- Murrells Inlet6
- Seneca6
Source: Doctors and Clinicians National Downloadable File (CMS)
Each South Carolina primary care group profile shows the parent, sites, clinicians and identifiers
- Clinicians and specialtiesA count by specialty and a sample of the group's cliniciansOn every profile
- Practice locationsMain site and a sample of practice locations, with a count of the restOn every profile
- Medicare Part B paymentsMedicare payments to the group, from CMSOn every profile
- Group NPI and Medicare PAC IDIdentifiers for matching records across sourcesOn every profile
- Parent organizationThe health system, platform or owner above the groupOn every profile
- Every clinician and siteThe full roster and every practice locationWith a free account
- Leader and clinician contactsWork emails and mobile numbers, found on request and then validatedWith a free account
- EHR used by the group's cliniciansThe EHR in use at the group's sitesWith a free account
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Sources: Doctors and Clinicians National Downloadable File (CMS), Medicare Physician & Other Practitioners (CMS) and Dmand AI Org Hierarchy Data
Sources for the South Carolina primary care group list
| Data on this page | Source |
|---|---|
| Medical groups, specialties and sites | Doctors and Clinicians National Downloadable File (CMS) and Dmand AI Professional Profile Data |
| Parent organizations and independence | Dmand AI Org Hierarchy Data |
| Physicians and HCPs | Dmand AI Affiliation Data |
| Group NPI and PAC ID | NPPES NPI Registry (CMS) and Doctors and Clinicians National Downloadable File (CMS) |
Data last refreshed October 2026Report an inaccuracyRemove my information
Groups whose main specialty is primary care and that have a Medicare PAC ID.
FAQ
Frequently asked questions about primary care groups in South Carolina
Spotted something out of date? Email hello@dmand.ai and we will check the record. Contact details live in the free trial.
What is the largest internal medicine group in South Carolina?
Prisma Health Medical Group, based in Greenville, with 369 internal medicine specialists and 3,382 HCPs. MUSC Health is second with 320.
What is the largest nurse practitioner group in South Carolina?
CVS MinuteClinic, based in Simpsonville, with 99 nurse practitioner specialists and 102 HCPs. Empatia Palliative Care is second with 18.
How many primary care groups are in South Carolina?
There are 448 primary care groups in South Carolina with a Medicare PAC ID: 177 internal medicine, 123 nurse practitioner, 122 family medicine and 25 physician assistant. Between them they have 2,361 internal medicine specialists, 379 nurse practitioner specialists, 639 family physicians and 40 physician assistant specialists.
Which companies own the most primary care groups?
By physicians, Prisma Health, with 2,811 across 5 groups, followed by Medical University of South Carolina with 2,480 and Bon Secours Mercy Health with 716.
How many South Carolina primary care groups are independent?
276, or 62%, have no larger parent organization in the Dmand AI org hierarchy. 74 belong to a health system or hospital and 28 to a physician platform or corporate owner.
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