Dr. Paul Edward O'Brien, MD

  • Charleston, SC
  • Medical oncologist
NPI1902914864PAC ID2860401858
Medicare services, 2024
422
Medicare patients, 2024
218
Part D claims, 2024
882
Publications
74
Clinical trials
8
Practice address
171 Ashley Ave, Charleston, SC 29425
Practice phone
Call (843) 792-1414
Professional email
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Personal email
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Mobile number
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Social profiles

Primary practice

MUSC University Hospital

Charleston, South Carolina

See all 7 affiliations

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Dr. Paul Edward O'Brien is a medical oncologist in Charleston, South Carolina

Dr. O'Brien practices at MUSC University Hospital in Charleston, South Carolina.

Dr. O'Brien's NPI, 1902914864, was assigned on August 29, 2006. Dr. O'Brien graduated from Northwestern University Feinberg Medical School in 1996. Dr. O'Brien holds South Carolina license 28587.

NPI and contact details
Medicare PAC ID
2860401858
NPI enumeration date
August 29, 2006
NPI status
Active
Accepts Medicare assignment
Yes
Offers telehealth
Yes
Practice phone
(843) 792-1414
Professional email
Get email
Personal email
Get email
Mobile number
Get number
Sex
Male
Estimated age
56
Medical school graduation
1996

Sources: NPPES NPI Registry (CMS); Dmand AI Professional Profile Data; Dmand AI Practice Data; and Doctors and Clinicians National Downloadable File (CMS)

Dr. Paul Edward O'Brien practices at MUSC University Hospital in Charleston, South Carolina

Dr. O'Brien's primary practice is MUSC University Hospital, at 171 Ashley Ave, Charleston, SC 29425 in Charleston County. The practice phone is (843) 792-1414.

  • MUSC University Hospital
    171 Ashley Ave, Charleston, SC 29425 · Charleston CountyPhone(843) 792-1414

Sources: NPPES NPI Registry (CMS); and Dmand AI Practice Data

Dr. Paul Edward O'Brien is affiliated with 6 sites of care and 1 medical group

Dr. O'Brien's primary practice is MUSC University Hospital in Charleston, South Carolina. Dr. O'Brien is also affiliated with MUSC Health University Medical Center. The medical group on file is MUSC Health. Dmand AI also links Dr. O'Brien to 2 more hospitals, 1 group practice or clinic and 1 home health agency, each named with a free account.

See all 7 affiliations for Dr. O'Brien

Sources: NPPES NPI Registry (CMS); Dmand AI Practice Data; and Dmand AI Affiliation Data

Dmand AI tracks the EHR system at Dr. Paul Edward O'Brien's practice

Dmand AI tracks the electronic health record (EHR) system at each site where Dr. O'Brien practices, 5 sites in all. Vendor and product names are available with a free account.

EHR by site
SiteEHR vendor and product
MUSC University HospitalAvailable with a free account
+5 more affiliated sitesAvailable with a free account

Source: Dmand AI Technology Install Data

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Dr. Paul Edward O'Brien is one of 31 medical oncologists in South Carolina

Medical oncology is Dr. O'Brien's primary specialty in the NPI Registry, under taxonomy code 207RX0202X. Dr. O'Brien is licensed in South Carolina.

Specialties and state licenses

  • Medical oncology, South CarolinaPrimaryLicense 28587 · taxonomy 207RX0202X

Medical oncologists near Dr. O'Brien

Counts of medical oncologists with a Dmand AI profile, by place and practice. Each opens the list.

Sources: NPPES NPI Registry (CMS); Dmand AI Professional Profile Data; and Dmand AI Peer Benchmarks

Dr. Paul Edward O'Brien billed Medicare for 422 services in 2024

CMS data shows 422 Medicare services from Dr. O'Brien across 6 procedure codes in 2024, for 218 Medicare patients. Medicare paid $31,281 for them.

Medicare services, 2024422
Medicare patients218
Paid by Medicare$31,281
Procedure codes6

Dr. O'Brien's Medicare services by type, 2023 to 2024

  • 2023
  • 2024
Office and hospital visits
2023: 4782024: 42212%
Tests and treatments
2023: 112024: 0100%
Other services
2023: 362024: 0100%

Where Dr. O'Brien's Medicare services took place, 2024

  • In an office6415%
  • In a facility35885%

Dr. O'Brien compared with the South Carolina median for medical oncologists, 2024

  • Dr. O'Brien
  • South Carolina median
Medicare services
422vs 71041% below
Medicare patients
218vs 24712% below
Part D claims
701vs 47448% above

Medians across 30 medical oncologists in South Carolina with Dmand AI profiles that report each measure.

Dr. O'Brien's most billed Medicare procedure codes, 2024

CMS publishes codes billed for 11 or more Medicare patients. Each label is the code family; CPT descriptions are licensed by the AMA.

See all procedures by Dr. O'Brien

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Sources: Medicare Physician & Other Practitioners - by Provider and Service (CMS), 2024 data; and Dmand AI Peer Benchmarks

Dr. Paul Edward O'Brien treated 218 Medicare patients in 2024, average age 73

CMS counts 218 Medicare patients who saw Dr. O'Brien in 2024. The largest group is 65 to 74, with 118 patients. 75% of them have high blood pressure, and 74% have high cholesterol. 7% are also on Medicaid. Their average risk score is 2.35, where 1.00 is the Medicare average, so they are sicker than most Medicare patients.

Across all payers, Dmand AI patient panel data puts Dr. O'Brien's median patient age at 68, with 47% women.

Medicare patients, 2024218
Average age73
Average risk score2.35
Also on Medicaid7%

Dr. O'Brien's Medicare patients by age, 2024

CMS leaves out age groups with fewer than 11 patients.

Dr. O'Brien's Medicare patients by sex, 2024

  • Women10950%
  • Men10950%

Chronic conditions among Dr. O'Brien's Medicare patients, 2024

  1. High blood pressure75%
  2. High cholesterol74%
  3. Cancer50%
  4. Arthritis40%
  5. Diabetes38%
  6. Chronic kidney disease30%
  7. Ischemic heart disease27%
  8. Anxiety25%

Share of Medicare patients with each condition. A patient can have several.

Dr. O'Brien's patients across all payers

Dmand AI patient panel data covers Medicare, Medicaid and commercial patients.

Patient panel by age, all payers

Median age 68

Patient panel by sex, all payers

  • Women47%
  • Men53%

Sources: Dmand AI Patient Panel Data; and Medicare Physician & Other Practitioners - by Provider (CMS), 2024 data

Dr. Paul Edward O'Brien wrote 882 Medicare Part D claims in 2024

In 2024, Dr. O'Brien wrote 882 Medicare Part D claims for 159 patients. 70% of them were for generic drugs. CMS names the drug for 701 of them, across 21 drugs with 11 or more claims each, at $1,283,395 in total drug cost. In 2023, CMS named 675 claims across 20 drugs.

Part D claims, 2024882
Drugs named by CMS21
Total drug cost$1.3M
Part D patients159

Dr. O'Brien's Part D claims by kind of drug, 2024

  • Generic619 claims70%
  • Brand-name and other263 claims30%

Dr. O'Brien's most prescribed drugs by claims, 2024

CMS names a drug when it has 11 or more claims. Share is of the claims for drugs CMS names.

Drug classes CMS tracks in Dr. O'Brien's Part D claims, 2024

  • Opioids12%104 of 882 claims

Share of all Part D claims for each drug class CMS reports on. Classes with no claims are left out.

Part D claims for drugs CMS names, 2023 to 2024

  • 2023
  • 2024
Claims for drugs CMS names
2023: 6752024: 7014%

Drugs named by CMS: 21 in 2024, 20 in 2023.

See all prescribing by Dr. O'Brien

Sources: Medicare Part D Prescribers - by Provider and Drug (CMS), 2024 data, released May 6, 2026; and Medicare Part D Prescribers - by Provider (CMS), 2024 data

Dr. Paul Edward O'Brien offers telehealth to Medicare patients

Dr. O'Brien accepts Medicare assignment, so Medicare's approved amount is taken as full payment. CMS lists Dr. O'Brien as offering telehealth.

Accepts Medicare assignment
Yes
Offers telehealth
Yes

Source: Doctors and Clinicians National Downloadable File (CMS)

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Dr. Paul Edward O'Brien has 74 publications on record

Dmand AI links 74 papers to Dr. O'Brien, published from 2011 to 2024. 2012 was the busiest year, with 4. The most frequent topics are Weight Loss, Gastroplasty and Laparoscopy. Dr. O'Brien has published most often in Obes Surg. Dr. O'Brien's most frequent co-authors are Geraldine Ooi, Uzair Bashir Chaudhary, MD and Lori J. Wirth, MD.

Papers74
Years published2011 to 2024

Dr. O'Brien's papers by year, 2012 to 2024

Topics Dr. O'Brien writes about most

  • Weight Loss
  • Gastroplasty
  • Laparoscopy
  • Obesity, Morbid
  • Obesity
  • Bariatric Surgery
  • Australia
  • Body Mass Index

Dr. O'Brien's most frequent co-authors

Recent publications by Dr. O'Brien

See all 74 publications and co-authors

See who Dr. O'Brien researches with

Physician Network Discovery turns co-authorship, shared hospitals and shared groups into a map of who Dr. O'Brien works with, so you can find a warm path to the right medical oncologists.

How network discovery works

Sources: PubMed (National Library of Medicine); and Dmand AI Research Linkage

Dr. Paul Edward O'Brien has worked on 8 clinical trials

Dmand AI links Dr. O'Brien to 8 clinical trials, 4 of them phase 2 studies. 5 are still active or recruiting. Conditions studied include Anal Canal Carcinoma, Colorectal Neoplasms, Hereditary Nonpolyposis and Head and Neck Neoplasms. Alliance for Clinical Trials in Oncology sponsors the most, 4.

Clinical trials with Dr. O'Brien by phase

  1. NonePhase 1: no trials
  2. 4Phase 2: 4 trials
  3. 1Phase 2/3: 1 trial
  4. 3Phase 3: 3 trials
  5. NonePhase 4: no trials

Conditions in Dr. O'Brien's trials

  • Anal Canal Carcinoma
  • Colorectal Neoplasms, Hereditary Nonpolyposis
  • Head and Neck Neoplasms
  • Laryngeal Neoplasms
  • Rectal Diseases

Investigators on the most trials with Dr. O'Brien

Recent clinical trials with Dr. O'Brien

See all 8 clinical trials and co-investigators

Sources: Dmand AI Research Linkage; and ClinicalTrials.gov (National Library of Medicine)

Dr. Paul Edward O'Brien received $30 in industry payments in 2025

CMS Open Payments shows 1 general payment to Dr. O'Brien from 1 drug or device company in 2025. Food and beverage make up the largest share, 100% of the total. Novo Nordisk Inc paid the most, $30.

Companies that paid Dr. O'Brien the most, 2025 to 2025

Share is of all general payments to this clinician.

See all payments to Dr. O'Brien

Source: Open Payments (CMS), 2025 data, released July 7, 2026

Dr. Paul Edward O'Brien graduated from Northwestern University Feinberg Medical School

Dr. O'Brien graduated from Northwestern University Feinberg Medical School in 1996.

  1. Medical schoolNorthwestern University Feinberg Medical School

Source: Dmand AI Professional Profile Data

Sources for Dr. Paul Edward O'Brien's profile data

Sources for the data on this page
Data on this pageSource
NPI, name, sex, specialty and licensesNPPES NPI Registry (CMS) (opens in a new tab)Dmand AI Professional Profile Data
Practice locations and phoneNPPES NPI Registry (CMS) (opens in a new tab)Dmand AI Practice Data
Primary practice, affiliations and health systemNPPES NPI Registry (CMS) (opens in a new tab)Dmand AI Practice DataDmand AI Affiliation Data
Medicare services and procedure codesMedicare Physician & Other Practitioners - by Provider and Service (CMS) (opens in a new tab)
State medians for the same specialtyDmand AI Peer Benchmarks
Medicare patients and the all-payer patient panelDmand AI Patient Panel DataMedicare Physician & Other Practitioners - by Provider (CMS) (opens in a new tab)
Part D prescribingMedicare Part D Prescribers - by Provider and Drug (CMS) (opens in a new tab)Medicare Part D Prescribers - by Provider (CMS) (opens in a new tab)
MIPS scores, telehealth, assignment and procedure percentilesDoctors and Clinicians National Downloadable File (CMS) (opens in a new tab)
Publications, topics and co-authorsPubMed (National Library of Medicine) (opens in a new tab)Dmand AI Research Linkage
Clinical trials and co-investigatorsDmand AI Research LinkageClinicalTrials.gov (National Library of Medicine) (opens in a new tab)
Industry paymentsOpen Payments (CMS) (opens in a new tab)
Training, board certification and membershipsDmand AI Professional Profile Data
EHR at each practice siteDmand AI Technology Install Data
Similar physiciansDmand AI Affiliation Data

Data last refreshed October 2026Report an inaccuracyRemove my information

FAQ

Frequently asked questions about Dr. Paul Edward O'Brien

Spotted something out of date? Email hello@dmand.ai and we will check the record. Contact details live in the free trial.

What is Dr. Paul Edward O'Brien's NPI number?

Dr. Paul Edward O'Brien's NPI number is 1902914864. It was assigned on August 29, 2006, and it is active in the NPI Registry.

What kind of doctor is Dr. Paul Edward O'Brien?

Dr. Paul Edward O'Brien is a medical oncologist in Charleston, South Carolina. The primary specialty in the NPI Registry is Medical Oncology Physician (taxonomy code 207RX0202X).

Where does Dr. Paul Edward O'Brien practice?

Dr. O'Brien practices at 171 Ashley Ave, Charleston, SC 29425. Dr. O'Brien's primary practice is MUSC University Hospital in Charleston, South Carolina. Dmand AI also links Dr. O'Brien to 2 hospitals, 1 group practice or clinic and 1 home health agency.

What is Dr. Paul Edward O'Brien's office phone number?

The practice phone on file for Dr. O'Brien is (843) 792-1414.

What is Dr. Paul Edward O'Brien's medical license number?

Dr. O'Brien holds South Carolina license 28587.

Which hospitals is Dr. Paul Edward O'Brien affiliated with?

Dr. O'Brien is affiliated with MUSC Health University Medical Center. Dmand AI links Dr. O'Brien to 2 more hospitals.

What medical group is Dr. Paul Edward O'Brien part of?

Dr. O'Brien is linked to MUSC Health.

Does Dr. Paul Edward O'Brien accept Medicare?

Yes. CMS data shows Dr. O'Brien billed Medicare for 422 services in 2024, and Dr. O'Brien accepts Medicare assignment.

Does Dr. Paul Edward O'Brien offer telehealth?

Yes. The CMS Doctors and Clinicians file lists Dr. O'Brien as offering telehealth services.

How many Medicare patients does Dr. Paul Edward O'Brien see?

CMS counts 218 Medicare patients who saw Dr. O'Brien in 2024, with an average age of 73.

Show 7 more questionsShow fewer questions

What services does Dr. Paul Edward O'Brien bill to Medicare?

In 2024, Dr. O'Brien's most billed Medicare services were office visit, established patient (99214), office visit, new patient (99205) and office visit, established patient (99213).

Where did Dr. Paul Edward O'Brien go to medical school?

Dr. O'Brien graduated from Northwestern University Feinberg Medical School in 1996.

What drugs does Dr. Paul Edward O'Brien prescribe most?

In 2024 Medicare Part D data, Dr. O'Brien's most prescribed drugs by claims were Ondansetron HCl, Creon and Oxycodone HCl.

Has Dr. Paul Edward O'Brien received payments from drug or device companies?

CMS Open Payments shows $30 in general payments to Dr. O'Brien from 1 company from 2025 to 2025. The largest total came from Novo Nordisk Inc.

How long has Dr. Paul Edward O'Brien been practicing?

Dr. O'Brien graduated from medical school in 1996, 30 years ago.

Does Dr. Paul Edward O'Brien do research?

Dmand AI links 74 publications to Dr. O'Brien, published from 2011 to 2024. Dr. O'Brien has worked on 8 clinical trials.

Who does Dr. Paul Edward O'Brien publish with?

Dr. O'Brien's most frequent co-authors are Geraldine Ooi (9 shared papers), Uzair Bashir Chaudhary, MD (2 shared papers) and Lori J. Wirth, MD (2 shared papers).

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