Dr. Charles L. Knupp, MD

  • Greenville, NC
  • Hematologist and oncologist
NPI1154313575PAC ID1557449261
Medicare services, 2024
397
Medicare patients, 2024
197
Part D claims, 2024
968
Publications
9
MIPS score, 2024
97
Practice address
2100 Stantonsburg Rd, Greenville, NC 27834
Practice phone
Call (252) 847-4100
Professional email
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Personal email
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Mobile number
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Social profiles

Primary practice

ECU Health Medical Center

Hospital · Greenville, North Carolina

See all 9 affiliations

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Dr. Charles L. Knupp is a hematologist and oncologist in Greenville, North Carolina

Dr. Knupp practices at ECU Health Medical Center in Greenville, North Carolina, part of University Health Systems of Eastern Carolina.

Dr. Knupp's NPI, 1154313575, was assigned on August 22, 2005. Dr. Knupp graduated from University of Maryland School of Medicine in 1976. Dr. Knupp holds North Carolina license 24433.

NPI and contact details
Medicare PAC ID
1557449261
NPI enumeration date
August 22, 2005
NPI status
Active
Accepts Medicare assignment
Yes
Practice phone
(252) 847-4100
Professional email
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Personal email
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Mobile number
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Sex
Male
Estimated age
76
Medical school graduation
1976

Sources: NPPES NPI Registry (CMS); Dmand AI Professional Profile Data; Dmand AI Affiliation Data; and Doctors and Clinicians National Downloadable File (CMS)

Dr. Charles L. Knupp practices at ECU Health Medical Center in Greenville, North Carolina

Dr. Knupp's primary practice is ECU Health Medical Center, at 2100 Stantonsburg Rd, Greenville, NC 27834 in Pitt County. The practice phone is (252) 847-4100.

Source: Dmand AI Affiliation Data

Dr. Charles L. Knupp is affiliated with 5 sites of care and 4 medical groups

Dr. Knupp's primary practice is ECU Health Medical Center in Greenville, North Carolina, part of University Health Systems of Eastern Carolina. The medical group on file is ECU Health. Dmand AI also links Dr. Knupp to 4 more group practices and clinics and 3 medical groups, each named with a free account.

See all 9 affiliations for Dr. Knupp

Sources: Dmand AI Affiliation Data; and Dmand AI Org Hierarchy Data

Dmand AI tracks the EHR system at Dr. Charles L. Knupp's practice

Dmand AI tracks the electronic health record (EHR) system at each site where Dr. Knupp practices, 5 sites in all. Vendor and product names are available with a free account.

EHR by site
SiteEHR vendor and product
ECU Health Medical CenterAvailable with a free account
+4 more sites and 3 medical groupsAvailable with a free account

Source: Dmand AI Technology Install Data

For health IT teams

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Dmand AI maps EHR vendors, IT decision makers and buying committees across University Health Systems of Eastern Carolina and 6.2K+ hospitals, with verified contacts in the same login.

Dr. Charles L. Knupp is one of 420 hematologists and oncologists in North Carolina

Hematology and oncology is Dr. Knupp's primary specialty in the NPI Registry, under taxonomy code 207RH0003X. Dr. Knupp is board certified in hematology by the American Board of Internal Medicine. Dr. Knupp is licensed in North Carolina.

Specialties and state licenses

  • Hematology and oncology, North CarolinaPrimaryLicense 24433 · taxonomy 207RH0003X

Hematologists and oncologists near Dr. Knupp

Counts of hematologists and oncologists with a Dmand AI profile, by place and practice. Each opens the list.

Sources: NPPES NPI Registry (CMS); Dmand AI Professional Profile Data; and Dmand AI Peer Benchmarks

Dr. Charles L. Knupp billed Medicare for 397 services in 2024

CMS data shows 397 Medicare services from Dr. Knupp across 5 procedure codes in 2024, for 197 Medicare patients. Medicare paid $28,949 for them. Every service was in a facility, such as a hospital, rather than an office.

Medicare services, 2024397
Medicare patients197
Paid by Medicare$28,949
Procedure codes5

Dr. Knupp's Medicare services by type, 2023 to 2024

  • 2023
  • 2024
Office and hospital visits
2023: 4162024: 3975%

Dr. Knupp compared with the North Carolina median for hematologists and oncologists, 2024

  • Dr. Knupp
  • North Carolina median
Medicare services
397vs 45012% below
Medicare patients
197vs 1809% above
Part D claims
779vs 3242.4 times

Medians across 402 hematologists and oncologists in North Carolina with Dmand AI profiles that report each measure.

Dr. Knupp's most billed Medicare procedure codes, 2024

CMS publishes codes billed for 11 or more Medicare patients. Each label is the code family; CPT descriptions are licensed by the AMA.

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Sources: Medicare Physician & Other Practitioners - by Provider and Service (CMS), 2024 data; and Dmand AI Peer Benchmarks

Dr. Charles L. Knupp treated 197 Medicare patients in 2024, average age 70

CMS counts 197 Medicare patients who saw Dr. Knupp in 2024. The largest group is 65 to 74, with 74 patients. 75% of them have high blood pressure, and 68% have high cholesterol. 21% are also on Medicaid. Their average risk score is 2.62, where 1.00 is the Medicare average, so they are sicker than most Medicare patients.

Across all payers, Dmand AI patient panel data puts Dr. Knupp's median patient age at 71, with 60% women.

Medicare patients, 2024197
Average age70
Average risk score2.62
Also on Medicaid21%

Dr. Knupp's Medicare patients by age, 2024

Dr. Knupp's Medicare patients by sex, 2024

  • Women10252%
  • Men9548%

Chronic conditions among Dr. Knupp's Medicare patients, 2024

  1. High blood pressure75%
  2. High cholesterol68%
  3. Arthritis54%
  4. Chronic kidney disease44%
  5. Ischemic heart disease40%
  6. Diabetes37%
  7. Heart failure36%
  8. Anxiety35%

Share of Medicare patients with each condition. A patient can have several.

Dr. Knupp's patients across all payers

Dmand AI patient panel data covers Medicare, Medicaid and commercial patients.

Patient panel by age, all payers

Median age 71

Patient panel by sex, all payers

  • Women60%
  • Men40%

Sources: Dmand AI Patient Panel Data; and Medicare Physician & Other Practitioners - by Provider (CMS), 2024 data

Dr. Charles L. Knupp wrote 968 Medicare Part D claims in 2024

In 2024, Dr. Knupp wrote 968 Medicare Part D claims for 100 patients. 77% of them were for generic drugs. CMS names the drug for 779 of them, across 26 drugs with 11 or more claims each, at $1,375,537 in total drug cost. In 2023, CMS named 806 claims across 24 drugs.

Part D claims, 2024968
Drugs named by CMS26
Total drug cost$1.4M
Part D patients100

Dr. Knupp's Part D claims by kind of drug, 2024

  • Generic746 claims77%
  • Brand-name222 claims23%

Dr. Knupp's most prescribed drugs by claims, 2024

CMS names a drug when it has 11 or more claims. Share is of the claims for drugs CMS names.

Drug classes CMS tracks in Dr. Knupp's Part D claims, 2024

  • Opioids45%431 of 968 claims

Share of all Part D claims for each drug class CMS reports on. Classes with no claims are left out.

Part D claims for drugs CMS names, 2023 to 2024

  • 2023
  • 2024
Claims for drugs CMS names
2023: 8062024: 7793%

Drugs named by CMS: 26 in 2024, 24 in 2023.

See all prescribing by Dr. Knupp

Sources: Medicare Part D Prescribers - by Provider and Drug (CMS), 2024 data, released May 6, 2026; and Medicare Part D Prescribers - by Provider (CMS), 2024 data

Dr. Charles L. Knupp scored 97 out of 100 in Medicare's MIPS program for 2024

CMS publishes a Merit-based Incentive Payment System (MIPS) score of 97 out of 100 for Dr. Knupp for performance year 2024, reported through an alternative payment model (APM). Dr. Knupp accepts Medicare assignment, so Medicare's approved amount is taken as full payment.

Accepts Medicare assignment
Yes

Dr. Knupp's MIPS scores, performance year 2024

  • 97of 100Final score
  • 82.4of 100Quality
  • 100of 100Promoting Interoperability
  • 40of 100Improvement Activities

Each score is out of 100. The final score weighs the categories CMS scored for this clinician.

Sources: Doctors and Clinicians National Downloadable File (CMS); and Clinician Public Reporting: Overall MIPS Performance (CMS), 2024 data, released September 10, 2026

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Dr. Charles L. Knupp has 9 publications on record

Dmand AI links 9 papers to Dr. Knupp, published from 2012 to 2016. 2013 was the busiest year, with 3. The most frequent topics are Anemia, Sickle Cell. Dr. Knupp's most frequent co-authors are Darla Kaye Liles, MD, Kenneth I. Ataga, MD and Sai Hemanth Chavala, MD.

Papers9
Years published2012 to 2016

Dr. Knupp's papers by year, 2012 to 2016

Topics Dr. Knupp writes about most

  • Anemia, Sickle Cell

Dr. Knupp's most frequent co-authors

Recent publications by Dr. Knupp

See all 9 publications and co-authors

See who Dr. Knupp researches with

Physician Network Discovery turns co-authorship, shared hospitals and shared groups into a map of who Dr. Knupp works with, so you can find a warm path to the right hematologists and oncologists.

How network discovery works

Sources: PubMed (National Library of Medicine); and Dmand AI Research Linkage

Dr. Charles L. Knupp received $73,290 in industry payments from 2016 to 2024

CMS Open Payments shows 94 general payments to Dr. Knupp from 33 drug and device companies from 2016 to 2024. Accredited education speaker fees make up the largest share, 98% of the total. Pfizer Inc. paid the most, $71,694.

General payments to Dr. Knupp by program year, 2016 to 2024

General payments to Dr. Knupp by kind, 2016 to 2024

$73.3Kin total
  • Accredited education speaker fees$71,64698%
  • Food and beverage$1,4602%
  • Education$1840%

Companies that paid Dr. Knupp the most, 2016 to 2024

Share is of all general payments to this clinician.

See all payments to Dr. Knupp

Source: Open Payments (CMS), 2025 data, released July 7, 2026

Dr. Charles L. Knupp graduated from University of Maryland School of Medicine

Dr. Knupp graduated from University of Maryland School of Medicine in 1976.

  1. Medical schoolUniversity of Maryland School of Medicine
  2. Board certified in hematologyAmerican Board of Internal Medicine
  3. Board certified in internal medicineAmerican Board of Internal Medicine

Source: Dmand AI Professional Profile Data

Sources for Dr. Charles L. Knupp's profile data

Sources for the data on this page
Data on this pageSource
NPI, name, sex, specialty and licensesNPPES NPI Registry (CMS) (opens in a new tab)Dmand AI Professional Profile Data
Practice locations and phoneDmand AI Affiliation Data
Primary practice, affiliations and health systemDmand AI Affiliation DataDmand AI Org Hierarchy Data
Medicare services and procedure codesMedicare Physician & Other Practitioners - by Provider and Service (CMS) (opens in a new tab)
State medians for the same specialtyDmand AI Peer Benchmarks
Medicare patients and the all-payer patient panelDmand AI Patient Panel DataMedicare Physician & Other Practitioners - by Provider (CMS) (opens in a new tab)
Part D prescribingMedicare Part D Prescribers - by Provider and Drug (CMS) (opens in a new tab)Medicare Part D Prescribers - by Provider (CMS) (opens in a new tab)
MIPS scores, telehealth, assignment and procedure percentilesDoctors and Clinicians National Downloadable File (CMS) (opens in a new tab)Clinician Public Reporting: Overall MIPS Performance (CMS) (opens in a new tab)
Publications, topics and co-authorsPubMed (National Library of Medicine) (opens in a new tab)Dmand AI Research Linkage
Industry paymentsOpen Payments (CMS) (opens in a new tab)
Training, board certification and membershipsDmand AI Professional Profile Data
EHR at each practice siteDmand AI Technology Install Data
Similar physiciansDmand AI Affiliation Data

Data last refreshed October 2026Report an inaccuracyRemove my information

FAQ

Frequently asked questions about Dr. Charles L. Knupp

Spotted something out of date? Email hello@dmand.ai and we will check the record. Contact details live in the free trial.

What is Dr. Charles L. Knupp's NPI number?

Dr. Charles L. Knupp's NPI number is 1154313575. It was assigned on August 22, 2005, and it is active in the NPI Registry.

What kind of doctor is Dr. Charles L. Knupp?

Dr. Charles L. Knupp is a hematologist and oncologist in Greenville, North Carolina. The primary specialty in the NPI Registry is Hematology & Oncology Physician (taxonomy code 207RH0003X).

Where does Dr. Charles L. Knupp practice?

Dr. Knupp practices at 2100 Stantonsburg Rd, Greenville, NC 27834. Dr. Knupp's primary practice is ECU Health Medical Center in Greenville, North Carolina, part of University Health Systems of Eastern Carolina. Dmand AI also links Dr. Knupp to 4 group practices and clinics and 3 medical groups.

What is Dr. Charles L. Knupp's office phone number?

The practice phone on file for Dr. Knupp is (252) 847-4100.

What is Dr. Charles L. Knupp's medical license number?

Dr. Knupp holds North Carolina license 24433.

Which hospitals is Dr. Charles L. Knupp affiliated with?

Dr. Knupp practices at ECU Health Medical Center in Greenville, North Carolina.

What medical group is Dr. Charles L. Knupp part of?

Dr. Knupp is linked to ECU Health. Dmand AI links Dr. Knupp to 3 more medical groups.

Does Dr. Charles L. Knupp accept Medicare?

Yes. CMS data shows Dr. Knupp billed Medicare for 397 services in 2024, and Dr. Knupp accepts Medicare assignment.

What is Dr. Charles L. Knupp's MIPS score?

Dr. Knupp's MIPS final score for performance year 2024 is 97 out of 100, reported through an alternative payment model (APM).

How many Medicare patients does Dr. Charles L. Knupp see?

CMS counts 197 Medicare patients who saw Dr. Knupp in 2024, with an average age of 70.

Show 8 more questionsShow fewer questions

Is Dr. Charles L. Knupp board certified?

Yes. Dr. Knupp is board certified in hematology by the American Board of Internal Medicine.

What services does Dr. Charles L. Knupp bill to Medicare?

In 2024, Dr. Knupp's most billed Medicare services were office visit, established patient (99214), hospital inpatient care (99232) and hospital inpatient care (99222).

Where did Dr. Charles L. Knupp go to medical school?

Dr. Knupp graduated from University of Maryland School of Medicine in 1976.

What drugs does Dr. Charles L. Knupp prescribe most?

In 2024 Medicare Part D data, Dr. Knupp's most prescribed drugs by claims were Oxycodone HCl, Hydroxyurea and Morphine Sulfate ER.

Has Dr. Charles L. Knupp received payments from drug or device companies?

CMS Open Payments shows $73,290 in general payments to Dr. Knupp from 33 companies from 2016 to 2024. The largest total came from Pfizer Inc.

How long has Dr. Charles L. Knupp been practicing?

Dr. Knupp graduated from medical school in 1976, 50 years ago.

Does Dr. Charles L. Knupp do research?

Dmand AI links 9 publications to Dr. Knupp, published from 2012 to 2016.

Who does Dr. Charles L. Knupp publish with?

Dr. Knupp's most frequent co-authors are Darla Kaye Liles, MD (7 shared papers), Kenneth I. Ataga, MD (1 shared paper) and Sai Hemanth Chavala, MD (1 shared paper).

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