Dr. Karam Al-Issa, MD

  • Indianapolis, IN
  • Hematologist and oncologist
NPI1720468259PAC ID0941502066
Medicare services, 2024
1,249
Medicare patients, 2024
342
Part D claims, 2024
873
MIPS score, 2024
85
Hospital affiliations
2
Practice address
1701 N Senate Blvd, Indianapolis, IN 46202
Practice phone
Call (317) 962-2000
Professional email
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Personal email
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Mobile number
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Social profiles

Primary practice

IU Health Methodist Hospital

Hospital · Indianapolis, Indiana

See all 7 affiliations

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Dr. Karam Al-Issa is a hematologist and oncologist in Indianapolis, Indiana

Dr. Al-Issa practices at IU Health Methodist Hospital in Indianapolis, Indiana, part of Indiana University Health.

Dr. Al-Issa's NPI, 1720468259, was assigned on May 29, 2015. Dr. Al-Issa holds Indiana license 01080058A.

NPI and contact details
Medicare PAC ID
0941502066
NPI enumeration date
May 29, 2015
NPI status
Active
Accepts Medicare assignment
Yes
Offers telehealth
Yes
Practice phone
(317) 962-2000
Professional email
Get email
Personal email
Get email
Mobile number
Get number
Sex
Male
Estimated age
39
Medical school graduation
2013

Sources: NPPES NPI Registry (CMS); Dmand AI Professional Profile Data; Dmand AI Affiliation Data; and Doctors and Clinicians National Downloadable File (CMS)

Dr. Karam Al-Issa practices at IU Health Methodist Hospital in Indianapolis, Indiana

Dr. Al-Issa's primary practice is IU Health Methodist Hospital, at 1701 N Senate Blvd, Indianapolis, IN 46202 in Marion County. The practice phone is (317) 962-2000.

Source: Dmand AI Affiliation Data

Dr. Karam Al-Issa is affiliated with 5 sites of care and 2 medical groups

Dr. Al-Issa's primary practice is IU Health Methodist Hospital in Indianapolis, Indiana, part of Indiana University Health. Dr. Al-Issa is also affiliated with IU Health North Hospital. The medical group on file is IU Health Medical Group. Dmand AI also links Dr. Al-Issa to 2 more group practices and clinics, 1 behavioral health center and 1 medical group, each named with a free account.

See all 7 affiliations for Dr. Al-Issa

Sources: Dmand AI Affiliation Data; and Dmand AI Org Hierarchy Data

Dmand AI tracks the EHR system at Dr. Karam Al-Issa's practice

Dmand AI tracks the electronic health record (EHR) system at each site where Dr. Al-Issa practices, 5 sites in all. Vendor and product names are available with a free account.

EHR by site
SiteEHR vendor and product
IU Health Methodist HospitalAvailable with a free account
+4 more sites and 1 medical groupAvailable with a free account

Source: Dmand AI Technology Install Data

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Dr. Karam Al-Issa is one of 224 hematologists and oncologists in Indiana

Hematology and oncology is Dr. Al-Issa's primary specialty in the NPI Registry, under taxonomy code 207RH0003X. Dr. Al-Issa is licensed in Indiana.

Specialties and state licenses

  • Hematology and oncology, IndianaPrimaryLicense 01080058A · taxonomy 207RH0003X

Hematologists and oncologists near Dr. Al-Issa

Counts of hematologists and oncologists with a Dmand AI profile, by place and practice. Each opens the list.

Sources: NPPES NPI Registry (CMS); Dmand AI Professional Profile Data; and Dmand AI Peer Benchmarks

Dr. Karam Al-Issa billed Medicare for 1,249 services in 2024

CMS data shows 1,249 Medicare services from Dr. Al-Issa across 6 procedure codes in 2024, for 342 Medicare patients. Medicare paid $101,117 for them.

Medicare services, 20241,249
Medicare patients342
Paid by Medicare$101,117
Procedure codes6

Dr. Al-Issa's Medicare services by type, 2023 to 2024

  • 2023
  • 2024
Office and hospital visits
2023: 1,0482024: 1,24919%

Where Dr. Al-Issa's Medicare services took place, 2024

  • In an office59848%
  • In a facility65152%

Dr. Al-Issa compared with the Indiana median for hematologists and oncologists, 2024

  • Dr. Al-Issa
  • Indiana median
Medicare services
1,249vs 76064% above
Medicare patients
342vs 26430% above
Part D claims
673vs 42359% above

Medians across 215 hematologists and oncologists in Indiana with Dmand AI profiles that report each measure.

Dr. Al-Issa's most billed Medicare procedure codes, 2024

CMS publishes codes billed for 11 or more Medicare patients. Each label is the code family; CPT descriptions are licensed by the AMA.

See all procedures by Dr. Al-Issa

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Sources: Medicare Physician & Other Practitioners - by Provider and Service (CMS), 2024 data; and Dmand AI Peer Benchmarks

Dr. Karam Al-Issa treated 342 Medicare patients in 2024, average age 72

CMS counts 342 Medicare patients who saw Dr. Al-Issa in 2024. The largest group is 65 to 74, with 173 patients. 75% of them have high blood pressure, and 71% have high cholesterol. 17% are also on Medicaid. Their average risk score is 1.80, where 1.00 is the Medicare average, so they are sicker than most Medicare patients.

Across all payers, Dmand AI patient panel data puts Dr. Al-Issa's median patient age at 61, with 63% women.

Medicare patients, 2024342
Average age72
Average risk score1.80
Also on Medicaid17%

Dr. Al-Issa's Medicare patients by age, 2024

Dr. Al-Issa's Medicare patients by sex, 2024

  • Women18153%
  • Men16147%

Chronic conditions among Dr. Al-Issa's Medicare patients, 2024

  1. High blood pressure75%
  2. High cholesterol71%
  3. Arthritis49%
  4. Diabetes41%
  5. Chronic kidney disease37%
  6. Mood disorders35%
  7. Anxiety33%
  8. Depression33%

Share of Medicare patients with each condition. A patient can have several.

Dr. Al-Issa's patients across all payers

Dmand AI patient panel data covers Medicare, Medicaid and commercial patients.

Patient panel by age, all payers

Median age 61

Patient panel by sex, all payers

  • Women63%
  • Men36%

Sources: Dmand AI Patient Panel Data; and Medicare Physician & Other Practitioners - by Provider (CMS), 2024 data

Dr. Karam Al-Issa wrote 873 Medicare Part D claims in 2024

In 2024, Dr. Al-Issa wrote 873 Medicare Part D claims for 181 patients. 64% of them were for generic drugs. CMS names the drug for 673 of them, across 24 drugs with 11 or more claims each, at $1,717,186 in total drug cost. In 2023, CMS named 380 claims across 15 drugs.

Part D claims, 2024873
Drugs named by CMS24
Total drug cost$1.7M
Part D patients181

Dr. Al-Issa's Part D claims by kind of drug, 2024

  • Generic555 claims64%
  • Brand-name318 claims36%

Dr. Al-Issa's most prescribed drugs by claims, 2024

CMS names a drug when it has 11 or more claims. Share is of the claims for drugs CMS names.

Drug classes CMS tracks in Dr. Al-Issa's Part D claims, 2024

  • Opioids6%56 of 873 claims
  • Antibiotics2%15 of 873 claims

Share of all Part D claims for each drug class CMS reports on. Classes with no claims are left out.

Part D claims for drugs CMS names, 2023 to 2024

  • 2023
  • 2024
Claims for drugs CMS names
2023: 3802024: 67377%

Drugs named by CMS: 24 in 2024, 15 in 2023.

See all prescribing by Dr. Al-Issa

Sources: Medicare Part D Prescribers - by Provider and Drug (CMS), 2024 data, released May 6, 2026; and Medicare Part D Prescribers - by Provider (CMS), 2024 data

Dr. Karam Al-Issa scored 85 out of 100 in Medicare's MIPS program for 2024

CMS publishes a Merit-based Incentive Payment System (MIPS) score of 85 out of 100 for Dr. Al-Issa for performance year 2024, reported individually. Dr. Al-Issa accepts Medicare assignment, so Medicare's approved amount is taken as full payment. CMS lists Dr. Al-Issa as offering telehealth.

Accepts Medicare assignment
Yes
Offers telehealth
Yes

Dr. Al-Issa's MIPS scores, performance year 2024

  • 85of 100Final score
  • 70.1of 100Quality
  • 40of 100Improvement Activities
  • 91of 100Cost

Each score is out of 100. The final score weighs the categories CMS scored for this clinician.

Sources: Doctors and Clinicians National Downloadable File (CMS); and Clinician Public Reporting: Overall MIPS Performance (CMS), 2024 data, released September 10, 2026

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Dr. Karam Al-Issa received $77,700 in industry payments from 2018 to 2025

CMS Open Payments shows 411 general payments to Dr. Al-Issa from 54 drug and device companies from 2018 to 2025. Speaker and faculty fees make up the largest share, 60% of the total. Seagen Inc. paid the most, $41,294.

General payments to Dr. Al-Issa by program year, 2018 to 2025

General payments to Dr. Al-Issa by kind, 2018 to 2025

$77.7Kin total
  • Speaker and faculty fees$46,96360%
  • Consulting fees$14,05818%
  • Food and beverage$11,75615%
  • Travel and lodging$4,0335%
  • Education$8901%

Companies that paid Dr. Al-Issa the most, 2018 to 2025

Share is of all general payments to this clinician.

See all payments to Dr. Al-Issa

Source: Open Payments (CMS), 2025 data, released July 7, 2026

Sources for Dr. Karam Al-Issa's profile data

Sources for the data on this page
Data on this pageSource
NPI, name, sex, specialty and licensesNPPES NPI Registry (CMS) (opens in a new tab)Dmand AI Professional Profile Data
Practice locations and phoneDmand AI Affiliation Data
Primary practice, affiliations and health systemDmand AI Affiliation DataDmand AI Org Hierarchy Data
Medicare services and procedure codesMedicare Physician & Other Practitioners - by Provider and Service (CMS) (opens in a new tab)
State medians for the same specialtyDmand AI Peer Benchmarks
Medicare patients and the all-payer patient panelDmand AI Patient Panel DataMedicare Physician & Other Practitioners - by Provider (CMS) (opens in a new tab)
Part D prescribingMedicare Part D Prescribers - by Provider and Drug (CMS) (opens in a new tab)Medicare Part D Prescribers - by Provider (CMS) (opens in a new tab)
MIPS scores, telehealth, assignment and procedure percentilesDoctors and Clinicians National Downloadable File (CMS) (opens in a new tab)Clinician Public Reporting: Overall MIPS Performance (CMS) (opens in a new tab)
Industry paymentsOpen Payments (CMS) (opens in a new tab)
EHR at each practice siteDmand AI Technology Install Data
Similar physiciansDmand AI Affiliation Data

Data last refreshed October 2026Report an inaccuracyRemove my information

FAQ

Frequently asked questions about Dr. Karam Al-Issa

Spotted something out of date? Email hello@dmand.ai and we will check the record. Contact details live in the free trial.

What is Dr. Karam Al-Issa's NPI number?

Dr. Karam Al-Issa's NPI number is 1720468259. It was assigned on May 29, 2015, and it is active in the NPI Registry.

What kind of doctor is Dr. Karam Al-Issa?

Dr. Karam Al-Issa is a hematologist and oncologist in Indianapolis, Indiana. The primary specialty in the NPI Registry is Hematology & Oncology Physician (taxonomy code 207RH0003X).

Where does Dr. Karam Al-Issa practice?

Dr. Al-Issa practices at 1701 N Senate Blvd, Indianapolis, IN 46202. Dr. Al-Issa's primary practice is IU Health Methodist Hospital in Indianapolis, Indiana, part of Indiana University Health. Dmand AI also links Dr. Al-Issa to 2 group practices and clinics, 1 behavioral health center and 1 medical group.

What is Dr. Karam Al-Issa's office phone number?

The practice phone on file for Dr. Al-Issa is (317) 962-2000.

What is Dr. Karam Al-Issa's medical license number?

Dr. Al-Issa holds Indiana license 01080058A.

Which hospitals is Dr. Karam Al-Issa affiliated with?

Dr. Al-Issa practices at IU Health Methodist Hospital in Indianapolis, Indiana. Dr. Al-Issa is also affiliated with IU Health North Hospital.

What medical group is Dr. Karam Al-Issa part of?

Dr. Al-Issa is linked to IU Health Medical Group. Dmand AI links Dr. Al-Issa to 1 more medical group.

Does Dr. Karam Al-Issa accept Medicare?

Yes. CMS data shows Dr. Al-Issa billed Medicare for 1,249 services in 2024, and Dr. Al-Issa accepts Medicare assignment.

Does Dr. Karam Al-Issa offer telehealth?

Yes. The CMS Doctors and Clinicians file lists Dr. Al-Issa as offering telehealth services.

What is Dr. Karam Al-Issa's MIPS score?

Dr. Al-Issa's MIPS final score for performance year 2024 is 85 out of 100, reported individually.

Show 5 more questionsShow fewer questions

How many Medicare patients does Dr. Karam Al-Issa see?

CMS counts 342 Medicare patients who saw Dr. Al-Issa in 2024, with an average age of 72.

What services does Dr. Karam Al-Issa bill to Medicare?

In 2024, Dr. Al-Issa's most billed Medicare services were office visit, established patient (99214), office visit, established patient (99215) and hospital inpatient care (99233).

What drugs does Dr. Karam Al-Issa prescribe most?

In 2024 Medicare Part D data, Dr. Al-Issa's most prescribed drugs by claims were Eliquis, Prochlorperazine Maleate and Anastrozole.

Has Dr. Karam Al-Issa received payments from drug or device companies?

CMS Open Payments shows $77,700 in general payments to Dr. Al-Issa from 54 companies from 2018 to 2025. The largest total came from Seagen Inc.

How long has Dr. Karam Al-Issa been practicing?

Dr. Al-Issa graduated from medical school in 2013, 13 years ago.

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