James A. Mastrianni

  • Chicago, IL
  • Neurologist
NPI1821149808PAC ID1951590710
Medicare services, 2024
332
Medicare patients, 2024
250
Part D claims, 2024
1,018
Publications
18
Clinical trials
4
Practice address
5721 S Maryland Ave, Chicago, IL 60637
Practice phone
Call (773) 702-1530
Professional email
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Personal email
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Mobile number
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Social profiles

Primary practice

Comer Children's Hospital - Hyde Park

Chicago, Illinois

See all 6 affiliations

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James A. Mastrianni is a neurologist in Chicago, Illinois

James Mastrianni practices at Comer Children's Hospital - Hyde Park in Chicago, Illinois.

James Mastrianni's NPI, 1821149808, was assigned on January 16, 2007. James Mastrianni holds Illinois license 036099006.

NPI and contact details
Medicare PAC ID
1951590710
NPI enumeration date
January 16, 2007
NPI status
Active
Accepts Medicare assignment
Yes
Offers telehealth
Yes
Practice phone
(773) 702-1530
Professional email
Get email
Personal email
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Mobile number
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Sex
Male
Estimated age
63
Medical school graduation
1989

Sources: NPPES NPI Registry (CMS); Dmand AI Professional Profile Data; Dmand AI Practice Data; and Doctors and Clinicians National Downloadable File (CMS)

James A. Mastrianni practices at Comer Children's Hospital - Hyde Park in Chicago, Illinois

James Mastrianni's primary practice is Comer Children's Hospital - Hyde Park, at 5721 S Maryland Ave, Chicago, IL 60637 in Cook County. The practice phone is (773) 702-1530.

  • Comer Children's Hospital - Hyde Park
    5721 S Maryland Ave, Chicago, IL 60637 · Cook CountyPhone(773) 702-1530

Sources: NPPES NPI Registry (CMS); and Dmand AI Practice Data

James A. Mastrianni is affiliated with 4 sites of care and 2 medical groups

James Mastrianni's primary practice is Comer Children's Hospital - Hyde Park in Chicago, Illinois. James Mastrianni is also affiliated with University of Chicago Medical Center. The medical group on file is UChicago Medicine Physicians. Dmand AI also links James Mastrianni to 2 more hospitals and 1 medical group, each named with a free account.

See all 6 affiliations for James Mastrianni

Sources: NPPES NPI Registry (CMS); Dmand AI Practice Data; Dmand AI Affiliation Data; and Dmand AI Org Hierarchy Data

Dmand AI tracks the EHR system at James A. Mastrianni's practice

Dmand AI tracks the electronic health record (EHR) system at each site where James Mastrianni practices, 3 sites in all. Vendor and product names are available with a free account.

EHR by site
SiteEHR vendor and product
Comer Children's Hospital - Hyde ParkAvailable with a free account
+3 more sites and 1 medical groupAvailable with a free account

Source: Dmand AI Technology Install Data

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James A. Mastrianni is one of 822 neurologists in Illinois

Neurology is James Mastrianni's primary specialty in the NPI Registry, under taxonomy code 2084N0400X. James Mastrianni is licensed in Illinois.

Specialties and state licenses

  • Neurology, IllinoisPrimaryLicense 036099006 · taxonomy 2084N0400X

Neurologists near James Mastrianni

Counts of neurologists with a Dmand AI profile, by place and practice. Each opens the list.

Sources: NPPES NPI Registry (CMS); Dmand AI Professional Profile Data; and Dmand AI Peer Benchmarks

James A. Mastrianni billed Medicare for 332 services in 2024

CMS data shows 332 Medicare services from James Mastrianni across 3 procedure codes in 2024, for 250 Medicare patients. Medicare paid $42,513 for them.

Medicare services, 2024332
Medicare patients250
Paid by Medicare$42,513
Procedure codes3

James Mastrianni's Medicare services by type, 2023 to 2024

  • 2023
  • 2024
Office and hospital visits
2023: 3492024: 3325%

Where James Mastrianni's Medicare services took place, 2024

  • In an office13440%
  • In a facility19860%

James Mastrianni compared with the Illinois median for neurologists, 2024

  • James Mastrianni
  • Illinois median
Medicare services
332vs 40117% below
Medicare patients
250vs 22511% above
Part D claims
929vs 3182.9 times

Medians across 747 neurologists in Illinois with Dmand AI profiles that report each measure.

James Mastrianni's most billed Medicare procedure codes, 2024

CMS publishes codes billed for 11 or more Medicare patients. Each label is the code family; CPT descriptions are licensed by the AMA.

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Sources: Medicare Physician & Other Practitioners - by Provider and Service (CMS), 2024 data; and Dmand AI Peer Benchmarks

James A. Mastrianni treated 250 Medicare patients in 2024, average age 76

CMS counts 250 Medicare patients who saw James Mastrianni in 2024. The largest group is 75 to 84, with 123 patients. 75% of them have high blood pressure, and 72% have high cholesterol. 29% are also on Medicaid. Their average risk score is 1.85, where 1.00 is the Medicare average, so they are sicker than most Medicare patients.

Across all payers, Dmand AI patient panel data puts James Mastrianni's median patient age at 78, with 58% women.

Medicare patients, 2024250
Average age76
Average risk score1.85
Also on Medicaid29%

James Mastrianni's Medicare patients by age, 2024

James Mastrianni's Medicare patients by sex, 2024

  • Women14257%
  • Men10843%

Chronic conditions among James Mastrianni's Medicare patients, 2024

  1. High blood pressure75%
  2. High cholesterol72%
  3. Alzheimer's and dementia68%
  4. Arthritis58%
  5. Mood disorders38%
  6. Anxiety36%
  7. Depression35%
  8. Diabetes34%

Share of Medicare patients with each condition. A patient can have several.

James Mastrianni's patients across all payers

Dmand AI patient panel data covers Medicare, Medicaid and commercial patients.

Patient panel by age, all payers

Median age 78

Patient panel by sex, all payers

  • Women58%
  • Men40%

Sources: Dmand AI Patient Panel Data; and Medicare Physician & Other Practitioners - by Provider (CMS), 2024 data

James A. Mastrianni wrote 1,018 Medicare Part D claims in 2024

In 2024, James Mastrianni wrote 1,018 Medicare Part D claims for 253 patients. 95% of them were for generic drugs. CMS names the drug for 929 of them, across 16 drugs with 11 or more claims each, at $36,553 in total drug cost. In 2023, CMS named 781 claims across 14 drugs.

Part D claims, 20241,018
Drugs named by CMS16
Total drug cost$36,553
Part D patients253

James Mastrianni's Part D claims by kind of drug, 2024

  • Generic966 claims95%
  • Brand-name52 claims5%

James Mastrianni's most prescribed drugs by claims, 2024

CMS names a drug when it has 11 or more claims. Share is of the claims for drugs CMS names.

Drug classes CMS tracks in James Mastrianni's Part D claims, 2024

  • Antipsychotics, patients 65 and over7%75 of 1,018 claims

Share of all Part D claims for each drug class CMS reports on. Classes with no claims are left out.

Part D claims for drugs CMS names, 2023 to 2024

  • 2023
  • 2024
Claims for drugs CMS names
2023: 7812024: 92919%

Drugs named by CMS: 16 in 2024, 14 in 2023.

See all prescribing by James Mastrianni

Sources: Medicare Part D Prescribers - by Provider and Drug (CMS), 2024 data, released May 6, 2026; and Medicare Part D Prescribers - by Provider (CMS), 2024 data

James A. Mastrianni offers telehealth to Medicare patients

James Mastrianni accepts Medicare assignment, so Medicare's approved amount is taken as full payment. CMS lists James Mastrianni as offering telehealth.

Accepts Medicare assignment
Yes
Offers telehealth
Yes

Source: Doctors and Clinicians National Downloadable File (CMS)

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James A. Mastrianni has 18 publications on record

Dmand AI links 18 papers to James Mastrianni, published from 2010 to 2023. 2018 was the busiest year, with 3. The most frequent topics are Mice, Transgenic, Prion Diseases and Alzheimer Disease. James Mastrianni has published most often in Front Neurol. James Mastrianni's most frequent co-authors are Kaitlin Seibert, MD, Stephen J. Dearmond, MD and Adil Javed.

Papers18
Years published2010 to 2023

James Mastrianni's papers by year, 2010 to 2023

Topics James Mastrianni writes about most

  • Mice, Transgenic
  • Prion Diseases
  • Alzheimer Disease
  • Prions
  • Brain
  • Cognitive Dysfunction
  • Deer
  • Disease Models, Animal

James Mastrianni's most frequent co-authors

Recent publications by James Mastrianni

See all 18 publications and co-authors

See who James Mastrianni researches with

Physician Network Discovery turns co-authorship, shared hospitals and shared groups into a map of who James Mastrianni works with, so you can find a warm path to the right neurologists.

How network discovery works

Sources: PubMed (National Library of Medicine); and Dmand AI Research Linkage

James A. Mastrianni has worked on 4 clinical trials

Dmand AI links James Mastrianni to 4 clinical trials. 2 are still active or recruiting. Conditions studied include Alzheimer Disease, Tauopathies and Plaque, Amyloid. AstraZeneca sponsors the most, 2. Open Payments lists research payments to James Mastrianni that name 2 trials.

Conditions in James Mastrianni's trials

  • Alzheimer Disease
  • Tauopathies
  • Plaque, Amyloid
  • Cognitive Dysfunction

Investigators on the most trials with James Mastrianni

Recent clinical trials with James Mastrianni

Sources: Open Payments (CMS), 2025 data, released July 7, 2026; Dmand AI Research Linkage; and ClinicalTrials.gov (National Library of Medicine)

James A. Mastrianni received $6,654 in industry payments from 2017 to 2025

CMS Open Payments shows 9 general payments to James Mastrianni from 6 drug and device companies from 2017 to 2025. Consulting fees make up the largest share, 98% of the total. Ionis Pharmaceuticals, Inc. paid the most, $4,500. It also lists 2 research payments totaling $1,809 from 2018 to 2022, naming 2 clinical trials.

General payments to James Mastrianni by program year, 2017 to 2025

General payments to James Mastrianni by kind, 2017 to 2025

$6.7Kin total
  • Consulting fees$6,52598%
  • Food and beverage$891%
  • Education$401%

Companies that paid James Mastrianni the most, 2017 to 2025

Share is of all general payments to this clinician.

See all payments to James Mastrianni

Source: Open Payments (CMS), 2025 data, released July 7, 2026

Sources for James A. Mastrianni's profile data

Sources for the data on this page
Data on this pageSource
NPI, name, sex, specialty and licensesNPPES NPI Registry (CMS) (opens in a new tab)Dmand AI Professional Profile Data
Practice locations and phoneNPPES NPI Registry (CMS) (opens in a new tab)Dmand AI Practice Data
Primary practice, affiliations and health systemNPPES NPI Registry (CMS) (opens in a new tab)Dmand AI Practice DataDmand AI Affiliation DataDmand AI Org Hierarchy Data
Medicare services and procedure codesMedicare Physician & Other Practitioners - by Provider and Service (CMS) (opens in a new tab)
State medians for the same specialtyDmand AI Peer Benchmarks
Medicare patients and the all-payer patient panelDmand AI Patient Panel DataMedicare Physician & Other Practitioners - by Provider (CMS) (opens in a new tab)
Part D prescribingMedicare Part D Prescribers - by Provider and Drug (CMS) (opens in a new tab)Medicare Part D Prescribers - by Provider (CMS) (opens in a new tab)
MIPS scores, telehealth, assignment and procedure percentilesDoctors and Clinicians National Downloadable File (CMS) (opens in a new tab)
Publications, topics and co-authorsPubMed (National Library of Medicine) (opens in a new tab)Dmand AI Research Linkage
Clinical trials and co-investigatorsDmand AI Research LinkageClinicalTrials.gov (National Library of Medicine) (opens in a new tab)
Industry paymentsOpen Payments (CMS) (opens in a new tab)
EHR at each practice siteDmand AI Technology Install Data
Similar physiciansDmand AI Affiliation Data

Data last refreshed October 2026Report an inaccuracyRemove my information

FAQ

Frequently asked questions about James A. Mastrianni

Spotted something out of date? Email hello@dmand.ai and we will check the record. Contact details live in the free trial.

What is James A. Mastrianni's NPI number?

James A. Mastrianni's NPI number is 1821149808. It was assigned on January 16, 2007, and it is active in the NPI Registry.

What does James A. Mastrianni specialize in?

James A. Mastrianni is a neurologist in Chicago, Illinois. The primary specialty in the NPI Registry is Neurology Physician (taxonomy code 2084N0400X).

Where does James A. Mastrianni practice?

James Mastrianni practices at 5721 S Maryland Ave, Chicago, IL 60637. James Mastrianni's primary practice is Comer Children's Hospital - Hyde Park in Chicago, Illinois. Dmand AI also links James Mastrianni to 2 hospitals and 1 medical group.

What is James A. Mastrianni's office phone number?

The practice phone on file for James Mastrianni is (773) 702-1530.

What is James A. Mastrianni's medical license number?

James Mastrianni holds Illinois license 036099006.

Which hospitals is James A. Mastrianni affiliated with?

James Mastrianni is affiliated with University of Chicago Medical Center. Dmand AI links James Mastrianni to 2 more hospitals.

What medical group is James A. Mastrianni part of?

James Mastrianni is linked to UChicago Medicine Physicians. Dmand AI links James Mastrianni to 1 more medical group.

Does James A. Mastrianni accept Medicare?

Yes. CMS data shows James Mastrianni billed Medicare for 332 services in 2024, and James Mastrianni accepts Medicare assignment.

Does James A. Mastrianni offer telehealth?

Yes. The CMS Doctors and Clinicians file lists James Mastrianni as offering telehealth services.

How many Medicare patients does James A. Mastrianni see?

CMS counts 250 Medicare patients who saw James Mastrianni in 2024, with an average age of 76.

Show 6 more questionsShow fewer questions

What services does James A. Mastrianni bill to Medicare?

In 2024, James Mastrianni's most billed Medicare services were office visit, established patient (99215), office visit, new patient (99205) and hospital inpatient care (99223).

What drugs does James A. Mastrianni prescribe most?

In 2024 Medicare Part D data, James Mastrianni's most prescribed drugs by claims were Donepezil HCl, Sertraline HCl and Memantine HCl.

Has James A. Mastrianni received payments from drug or device companies?

CMS Open Payments shows $6,654 in general payments to James Mastrianni from 6 companies from 2017 to 2025. The largest total came from Ionis Pharmaceuticals, Inc.

How long has James A. Mastrianni been practicing?

James Mastrianni graduated from medical school in 1989, 37 years ago.

Does James A. Mastrianni do research?

Dmand AI links 18 publications to James Mastrianni, published from 2010 to 2023. James Mastrianni has worked on 4 clinical trials.

Who does James A. Mastrianni publish with?

James Mastrianni's most frequent co-authors are Kaitlin Seibert, MD (3 shared papers), Stephen J. Dearmond, MD (1 shared paper) and Adil Javed (1 shared paper).

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