Dr. Carlos Manuel Decastro III, MD

  • Durham, NC
  • Hematologist and oncologist
NPI1912080169PAC ID4183605629
Medicare services, 2024
578
Medicare patients, 2024
161
Part D claims, 2024
410
Clinical trials
1
Hospital affiliations
2
Practice address
2301 Erwin Rd, Durham, NC 27705
Practice phone
Call (919) 684-8111
Professional email
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Personal email
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Mobile number
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Social profiles

Primary practice

Duke University Hospital

Hospital · Durham, North Carolina

See all 4 affiliations

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Dr. Carlos Manuel Decastro III is a hematologist and oncologist in Durham, North Carolina

Dr. Decastro practices at Duke University Hospital in Durham, North Carolina, part of Duke University.

Dr. Decastro's NPI, 1912080169, was assigned on October 23, 2006. Dr. Decastro graduated from University of Texas Southwestern Medical School at Dallas in 1985. Dr. Decastro holds North Carolina license 33980.

NPI and contact details
Medicare PAC ID
4183605629
NPI enumeration date
October 23, 2006
NPI status
Active
Accepts Medicare assignment
Yes
Offers telehealth
Yes
Practice phone
(919) 684-8111
Professional email
Get email
Personal email
Get email
Mobile number
Get number
Sex
Male
Estimated age
67
Medical school graduation
1985

Sources: NPPES NPI Registry (CMS); Dmand AI Professional Profile Data; Dmand AI Affiliation Data; and Doctors and Clinicians National Downloadable File (CMS)

Dr. Carlos Manuel Decastro III practices at Duke University Hospital in Durham, North Carolina

Dr. Decastro's primary practice is Duke University Hospital, at 2301 Erwin Rd, Durham, NC 27705 in Durham County. The practice phone is (919) 684-8111.

Source: Dmand AI Affiliation Data

Dr. Carlos Manuel Decastro III is affiliated with 3 sites of care and 1 medical group

Dr. Decastro's primary practice is Duke University Hospital in Durham, North Carolina, part of Duke University. Dr. Decastro is also affiliated with Duke Regional Hospital. The medical group on file is Duke Health Integrated Practice. Dmand AI also links Dr. Decastro to 1 more group practice or clinic, named with a free account.

See all 4 affiliations for Dr. Decastro

Sources: Dmand AI Affiliation Data; and Dmand AI Org Hierarchy Data

Dmand AI tracks the EHR system at Dr. Carlos Manuel Decastro III's practice

Dmand AI tracks the electronic health record (EHR) system at each site where Dr. Decastro practices, 3 sites in all. Vendor and product names are available with a free account.

EHR by site
SiteEHR vendor and product
Duke University HospitalAvailable with a free account
+2 more affiliated sitesAvailable with a free account

Source: Dmand AI Technology Install Data

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Dr. Carlos Manuel Decastro III is one of 420 hematologists and oncologists in North Carolina

Hematology and oncology is Dr. Decastro's primary specialty in the NPI Registry, under taxonomy code 207RH0003X. Dr. Decastro is licensed in North Carolina.

Specialties and state licenses

  • Hematology and oncology, North CarolinaPrimaryLicense 33980 · taxonomy 207RH0003X

Hematologists and oncologists near Dr. Decastro

Counts of hematologists and oncologists with a Dmand AI profile, by place and practice. Each opens the list.

Sources: NPPES NPI Registry (CMS); Dmand AI Professional Profile Data; and Dmand AI Peer Benchmarks

Dr. Carlos Manuel Decastro III billed Medicare for 578 services in 2024

CMS data shows 578 Medicare services from Dr. Decastro across 4 procedure codes in 2024, for 161 Medicare patients. Medicare paid $27,321 for them. Every service was in an office.

Medicare services, 2024578
Medicare patients161
Paid by Medicare$27,321
Procedure codes4

Dr. Decastro's Medicare services by type, 2023 to 2024

  • 2023
  • 2024
Office and hospital visits
2023: 4152024: 33320%
Other services
2023: 02024: 245

Dr. Decastro compared with the North Carolina median for hematologists and oncologists, 2024

  • Dr. Decastro
  • North Carolina median
Medicare services
578vs 45028% above
Medicare patients
161vs 18011% below
Part D claims
273vs 32416% below

Medians across 402 hematologists and oncologists in North Carolina with Dmand AI profiles that report each measure.

Dr. Decastro's most billed Medicare procedure codes, 2024

CMS publishes codes billed for 11 or more Medicare patients. Each label is the code family; CPT descriptions are licensed by the AMA.

See all procedures by Dr. Decastro

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Sources: Medicare Physician & Other Practitioners - by Provider and Service (CMS), 2024 data; and Dmand AI Peer Benchmarks

Dr. Carlos Manuel Decastro III treated 161 Medicare patients in 2024, average age 73

CMS counts 161 Medicare patients who saw Dr. Decastro in 2024. The largest group is 65 to 74, with 71 patients. 73% of them have high blood pressure, and 68% have high cholesterol. Their average risk score is 2.45, where 1.00 is the Medicare average, so they are sicker than most Medicare patients.

Across all payers, Dmand AI patient panel data puts Dr. Decastro's median patient age at 75, with 48% women.

Medicare patients, 2024161
Average age73
Average risk score2.45

Dr. Decastro's Medicare patients by age, 2024

Dr. Decastro's Medicare patients by sex, 2024

  • Women7949%
  • Men8251%

Chronic conditions among Dr. Decastro's Medicare patients, 2024

  1. High blood pressure73%
  2. High cholesterol68%
  3. Arthritis37%
  4. Ischemic heart disease30%
  5. Anxiety25%
  6. Chronic kidney disease25%
  7. Mood disorders25%
  8. Depression24%

Share of Medicare patients with each condition. A patient can have several.

Dr. Decastro's patients across all payers

Dmand AI patient panel data covers Medicare, Medicaid and commercial patients.

Patient panel by age, all payers

Median age 75

Patient panel by sex, all payers

  • Women48%
  • Men52%

Sources: Dmand AI Patient Panel Data; and Medicare Physician & Other Practitioners - by Provider (CMS), 2024 data

Dr. Carlos Manuel Decastro III wrote 410 Medicare Part D claims in 2024

In 2024, Dr. Decastro wrote 410 Medicare Part D claims for 63 patients. 55% of them were for generic drugs. CMS names the drug for 273 of them, across 13 drugs with 11 or more claims each, at $2,516,776 in total drug cost. In 2023, CMS named 220 claims across 10 drugs.

Part D claims, 2024410
Drugs named by CMS13
Total drug cost$2.5M
Part D patients63

Dr. Decastro's Part D claims by kind of drug, 2024

  • Generic225 claims55%
  • Brand-name185 claims45%

Dr. Decastro's most prescribed drugs by claims, 2024

CMS names a drug when it has 11 or more claims. Share is of the claims for drugs CMS names.

Drug classes CMS tracks in Dr. Decastro's Part D claims, 2024

  • Opioids3%13 of 410 claims
  • Antibiotics5%20 of 410 claims

Share of all Part D claims for each drug class CMS reports on. Classes with no claims are left out.

Part D claims for drugs CMS names, 2023 to 2024

  • 2023
  • 2024
Claims for drugs CMS names
2023: 2202024: 27324%

Drugs named by CMS: 13 in 2024, 10 in 2023.

See all prescribing by Dr. Decastro

Sources: Medicare Part D Prescribers - by Provider and Drug (CMS), 2024 data, released May 6, 2026; and Medicare Part D Prescribers - by Provider (CMS), 2024 data

Dr. Carlos Manuel Decastro III offers telehealth to Medicare patients

Dr. Decastro accepts Medicare assignment, so Medicare's approved amount is taken as full payment. CMS lists Dr. Decastro as offering telehealth.

Accepts Medicare assignment
Yes
Offers telehealth
Yes

Source: Doctors and Clinicians National Downloadable File (CMS)

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Dr. Carlos Manuel Decastro III has worked on 1 clinical trial

Dmand AI links Dr. Decastro to 1 clinical trial. Conditions studied include Leukemia, Myelomonocytic, Chronic and Myelodysplastic-Myeloproliferative Diseases. Open Payments lists research payments to Dr. Decastro that name 2 trials.

Conditions in Dr. Decastro's trials

  • Leukemia, Myelomonocytic, Chronic
  • Myelodysplastic-Myeloproliferative Diseases

Investigators on the most trials with Dr. Decastro

Recent clinical trials with Dr. Decastro

Sources: Open Payments (CMS), 2025 data, released July 7, 2026; ClinicalTrials.gov (National Library of Medicine); and Dmand AI Research Linkage

Dr. Carlos Manuel Decastro III received $124,196 in industry payments from 2019 to 2025

CMS Open Payments shows 105 general payments to Dr. Decastro from 13 drug and device companies from 2019 to 2025. Consulting fees make up the largest share, 47% of the total. Alexion Pharmaceuticals, Inc. paid the most, $58,985. It also lists 17 research payments totaling $33,528 from 2016 to 2025, naming 2 clinical trials.

General payments to Dr. Decastro by program year, 2019 to 2025

General payments to Dr. Decastro by kind, 2019 to 2025

$124.2Kin total
  • Consulting fees$58,20747%
  • Speaker and faculty fees$44,20736%
  • Travel and lodging$7,9766%
  • Honoraria$6,4305%
  • Other$7,2176%

Companies that paid Dr. Decastro the most, 2019 to 2025

Share is of all general payments to this clinician.

See all payments to Dr. Decastro

Source: Open Payments (CMS), 2025 data, released July 7, 2026

Dr. Carlos Manuel Decastro III graduated from University of Texas Southwestern Medical School at Dallas

Dr. Decastro graduated from University of Texas Southwestern Medical School at Dallas in 1985.

  1. Medical schoolUniversity of Texas Southwestern Medical School at Dallas

Source: Dmand AI Professional Profile Data

Sources for Dr. Carlos Manuel Decastro III's profile data

Sources for the data on this page
Data on this pageSource
NPI, name, sex, specialty and licensesNPPES NPI Registry (CMS) (opens in a new tab)Dmand AI Professional Profile Data
Practice locations and phoneDmand AI Affiliation Data
Primary practice, affiliations and health systemDmand AI Affiliation DataDmand AI Org Hierarchy Data
Medicare services and procedure codesMedicare Physician & Other Practitioners - by Provider and Service (CMS) (opens in a new tab)
State medians for the same specialtyDmand AI Peer Benchmarks
Medicare patients and the all-payer patient panelDmand AI Patient Panel DataMedicare Physician & Other Practitioners - by Provider (CMS) (opens in a new tab)
Part D prescribingMedicare Part D Prescribers - by Provider and Drug (CMS) (opens in a new tab)Medicare Part D Prescribers - by Provider (CMS) (opens in a new tab)
MIPS scores, telehealth, assignment and procedure percentilesDoctors and Clinicians National Downloadable File (CMS) (opens in a new tab)
Clinical trials and co-investigatorsClinicalTrials.gov (National Library of Medicine) (opens in a new tab)Dmand AI Research Linkage
Industry paymentsOpen Payments (CMS) (opens in a new tab)
Training, board certification and membershipsDmand AI Professional Profile Data
EHR at each practice siteDmand AI Technology Install Data
Similar physiciansDmand AI Affiliation Data

Data last refreshed October 2026Report an inaccuracyRemove my information

FAQ

Frequently asked questions about Dr. Carlos Manuel Decastro III

Spotted something out of date? Email hello@dmand.ai and we will check the record. Contact details live in the free trial.

What is Dr. Carlos Manuel Decastro III's NPI number?

Dr. Carlos Manuel Decastro III's NPI number is 1912080169. It was assigned on October 23, 2006, and it is active in the NPI Registry.

What kind of doctor is Dr. Carlos Manuel Decastro III?

Dr. Carlos Manuel Decastro III is a hematologist and oncologist in Durham, North Carolina. The primary specialty in the NPI Registry is Hematology & Oncology Physician (taxonomy code 207RH0003X).

Where does Dr. Carlos Manuel Decastro III practice?

Dr. Decastro practices at 2301 Erwin Rd, Durham, NC 27705. Dr. Decastro's primary practice is Duke University Hospital in Durham, North Carolina, part of Duke University. Dmand AI also links Dr. Decastro to 1 group practice or clinic.

What is Dr. Carlos Manuel Decastro III's office phone number?

The practice phone on file for Dr. Decastro is (919) 684-8111.

What is Dr. Carlos Manuel Decastro III's medical license number?

Dr. Decastro holds North Carolina license 33980.

Which hospitals is Dr. Carlos Manuel Decastro III affiliated with?

Dr. Decastro practices at Duke University Hospital in Durham, North Carolina. Dr. Decastro is also affiliated with Duke Regional Hospital.

What medical group is Dr. Carlos Manuel Decastro III part of?

Dr. Decastro is linked to Duke Health Integrated Practice.

Does Dr. Carlos Manuel Decastro III accept Medicare?

Yes. CMS data shows Dr. Decastro billed Medicare for 578 services in 2024, and Dr. Decastro accepts Medicare assignment.

Does Dr. Carlos Manuel Decastro III offer telehealth?

Yes. The CMS Doctors and Clinicians file lists Dr. Decastro as offering telehealth services.

How many Medicare patients does Dr. Carlos Manuel Decastro III see?

CMS counts 161 Medicare patients who saw Dr. Decastro in 2024, with an average age of 73.

Show 6 more questionsShow fewer questions

What services does Dr. Carlos Manuel Decastro III bill to Medicare?

In 2024, Dr. Decastro's most billed Medicare services were medicare service (G2211), office visit, established patient (99214) and office visit, established patient (99215).

Where did Dr. Carlos Manuel Decastro III go to medical school?

Dr. Decastro graduated from University of Texas Southwestern Medical School at Dallas in 1985.

What drugs does Dr. Carlos Manuel Decastro III prescribe most?

In 2024 Medicare Part D data, Dr. Decastro's most prescribed drugs by claims were Imatinib Mesylate, Inqovi and Cyclosporine Modified.

Has Dr. Carlos Manuel Decastro III received payments from drug or device companies?

CMS Open Payments shows $124,196 in general payments to Dr. Decastro from 13 companies from 2019 to 2025. The largest total came from Alexion Pharmaceuticals, Inc.

How long has Dr. Carlos Manuel Decastro III been practicing?

Dr. Decastro graduated from medical school in 1985, 41 years ago.

Does Dr. Carlos Manuel Decastro III do research?

Dr. Decastro has worked on 1 clinical trial.

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