Dr. Nicholas J. Zarkadis, DO

  • Saint Peters, MO
  • Orthopedic surgeon
NPI1033558259PAC ID3375957970
Medicare patients, 2024
73
Part D claims, 2024
247
Publications
12
Hospital affiliations
5
Industry payments
$26,694
Practice address
114 Piper Hill Dr, Saint Peters, MO 63376
Practice phone
Call (636) 928-1670
Professional email
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Personal email
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Mobile number
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Social profiles

Primary practice

St Peters Ambulatory Surgery Center

Saint Peters, Missouri

See all 10 affiliations

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Dr. Nicholas J. Zarkadis is an orthopedic surgeon in Saint Peters, Missouri

Dr. Zarkadis practices at St Peters Ambulatory Surgery Center in Saint Peters, Missouri.

Dr. Zarkadis' NPI, 1033558259, was assigned on June 20, 2013. Dr. Zarkadis holds Missouri license 2019016580.

NPI and contact details
Medicare PAC ID
3375957970
NPI enumeration date
June 20, 2013
NPI status
Active
Accepts Medicare assignment
Yes
Practice phone
(636) 928-1670
Professional email
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Personal email
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Mobile number
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Sex
Male
Estimated age
39
Medical school graduation
2013

Sources: NPPES NPI Registry (CMS); Dmand AI Professional Profile Data; Dmand AI Practice Data; and Doctors and Clinicians National Downloadable File (CMS)

Dr. Nicholas J. Zarkadis practices at St Peters Ambulatory Surgery Center in Saint Peters, Missouri

Dr. Zarkadis' primary practice is St Peters Ambulatory Surgery Center, at 114 Piper Hill Dr, Saint Peters, MO 63376 in Saint Charles County. The practice phone is (636) 928-1670.

  • St Peters Ambulatory Surgery Center
    114 Piper Hill Dr, Saint Peters, MO 63376 · Saint Charles CountyPhone(636) 928-1670

Sources: NPPES NPI Registry (CMS); and Dmand AI Practice Data

Dr. Nicholas J. Zarkadis is affiliated with 8 sites of care and 2 medical groups

Dr. Zarkadis' primary practice is St Peters Ambulatory Surgery Center in Saint Peters, Missouri. Dr. Zarkadis is also affiliated with Barnes-Jewish St. Peters Hospital. The medical group on file is Advanced Bone & Joint. Dmand AI also links Dr. Zarkadis to 4 more hospitals, 2 group practices and clinics and 1 medical group, each named with a free account.

See all 10 affiliations for Dr. Zarkadis

Sources: NPPES NPI Registry (CMS); Dmand AI Practice Data; and Dmand AI Affiliation Data

Dmand AI tracks the EHR system at Dr. Nicholas J. Zarkadis' practice

Dmand AI tracks the electronic health record (EHR) system at each site where Dr. Zarkadis practices, 7 sites in all. Vendor and product names are available with a free account.

EHR by site
SiteEHR vendor and product
St Peters Ambulatory Surgery CenterAvailable with a free account
+7 more sites and 1 medical groupAvailable with a free account

Source: Dmand AI Technology Install Data

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Dr. Nicholas J. Zarkadis is one of 417 orthopedic surgeons in Missouri

Orthopaedic surgery is Dr. Zarkadis' primary specialty in the NPI Registry, under taxonomy code 207X00000X. Dmand AI has Dr. Zarkadis' licenses on file in 2 states: Missouri and Nebraska.

Specialties and state licenses

  • Orthopaedic surgery, MissouriPrimaryLicense 2019016580 · taxonomy 207X00000X
  • Nebraska licenseLicense 1205

Orthopedic surgeons near Dr. Zarkadis

Counts of orthopedic surgeons with a Dmand AI profile, by place and practice. Each opens the list.

417orthopedic surgeons in Missouri
7orthopedic surgeons in Saint Peters

Sources: NPPES NPI Registry (CMS); Dmand AI Professional Profile Data; and Dmand AI Peer Benchmarks

Dr. Nicholas J. Zarkadis treated 73 Medicare patients in 2024, average age 75

CMS counts 73 Medicare patients who saw Dr. Zarkadis in 2024. The largest group is 65 to 74, with 35 patients. 75% of them have arthritis, and 75% have high blood pressure. 15% are also on Medicaid. Their average risk score is 1.27, where 1.00 is the Medicare average.

Across all payers, Dmand AI patient panel data puts Dr. Zarkadis' median patient age at 64, with 61% women.

Medicare patients, 202473
Average age75
Average risk score1.27
Also on Medicaid15%

Dr. Zarkadis' Medicare patients by age, 2024

CMS leaves out age groups with fewer than 11 patients.

Dr. Zarkadis' Medicare patients by sex, 2024

  • Women5170%
  • Men2230%

Chronic conditions among Dr. Zarkadis' Medicare patients, 2024

  1. Arthritis75%
  2. High blood pressure75%
  3. High cholesterol75%
  4. Diabetes38%
  5. Anxiety30%
  6. Depression30%
  7. Mood disorders29%
  8. Chronic kidney disease26%

Share of Medicare patients with each condition. A patient can have several.

Dr. Zarkadis' patients across all payers

Dmand AI patient panel data covers Medicare, Medicaid and commercial patients.

Patient panel by age, all payers

Median age 64

Patient panel by sex, all payers

  • Women61%
  • Men39%

Sources: Dmand AI Patient Panel Data; and Medicare Physician & Other Practitioners - by Provider (CMS), 2024 data

Dr. Nicholas J. Zarkadis wrote 247 Medicare Part D claims in 2024

In 2024, Dr. Zarkadis wrote 247 Medicare Part D claims for 63 patients. 97% of them were for generic drugs. CMS names the drug for 214 of them, across 5 drugs with 11 or more claims each, at $855 in total drug cost.

Part D claims, 2024247
Drugs named by CMS5
Total drug cost$855
Part D patients63

Dr. Zarkadis' Part D claims by kind of drug, 2024

  • Generic239 claims97%
  • Brand-name and other8 claims3%

Dr. Zarkadis' most prescribed drugs by claims, 2024

CMS names a drug when it has 11 or more claims. Share is of the claims for drugs CMS names.

Drug classes CMS tracks in Dr. Zarkadis' Part D claims, 2024

  • Opioids41%102 of 247 claims

Share of all Part D claims for each drug class CMS reports on. Classes with no claims are left out.

See all prescribing by Dr. Zarkadis

Sources: Medicare Part D Prescribers - by Provider and Drug (CMS), 2024 data, released May 6, 2026; and Medicare Part D Prescribers - by Provider (CMS), 2024 data

Dr. Nicholas J. Zarkadis ranks in the 59th percentile for hip replacement in Medicare

Dr. Zarkadis accepts Medicare assignment, so Medicare's approved amount is taken as full payment. CMS counts 15 procedures of hip replacement by Dr. Zarkadis, more than 59% of the clinicians it reports for that procedure.

Accepts Medicare assignment
Yes

Where Dr. Zarkadis ranks in Medicare procedure volume

Hip replacement
59th percentile15 procedures

CMS ranks each clinician against every clinician it reports for the same procedure category.

Knee replacement: 1 to 10 procedures (CMS shows small counts as a range)

Sources: Doctors and Clinicians National Downloadable File (CMS); and Doctors and Clinicians Utilization Data (CMS)

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Dr. Nicholas J. Zarkadis has 12 publications on record

Dmand AI links 12 papers to Dr. Zarkadis, published from 2013 to 2024. 2017 was the busiest year, with 3. Dr. Zarkadis has published most often in J Orthop. Dr. Zarkadis' most frequent co-authors are Nicholas Anthony Kusnezov, MD, Mark Peter Pallis, DO and Gautham Sivaraj Prabhakar, MD.

Papers12
Years published2013 to 2024

Dr. Zarkadis' papers by year, 2013 to 2024

Dr. Zarkadis' most frequent co-authors

Recent publications by Dr. Zarkadis

See all 12 publications and co-authors

See who Dr. Zarkadis researches with

Physician Network Discovery turns co-authorship, shared hospitals and shared groups into a map of who Dr. Zarkadis works with, so you can find a warm path to the right orthopedic surgeons.

How network discovery works

Sources: PubMed (National Library of Medicine); and Dmand AI Research Linkage

Dr. Nicholas J. Zarkadis received $26,694 in industry payments from 2017 to 2025

CMS Open Payments shows 86 general payments to Dr. Zarkadis from 11 drug and device companies from 2017 to 2025. Grants make up the largest share, 56% of the total. Smith & Nephew, Inc. paid the most, $15,893.

General payments to Dr. Zarkadis by program year, 2017 to 2025

General payments to Dr. Zarkadis by kind, 2017 to 2025

$26.7Kin total
  • Grants$15,00056%
  • Education$4,51117%
  • Food and beverage$4,39316%
  • Travel and lodging$2,79010%

Companies that paid Dr. Zarkadis the most, 2017 to 2025

Share is of all general payments to this clinician.

See all payments to Dr. Zarkadis

Source: Open Payments (CMS), 2025 data, released July 7, 2026

Sources for Dr. Nicholas J. Zarkadis's profile data

Sources for the data on this page
Data on this pageSource
NPI, name, sex, specialty and licensesNPPES NPI Registry (CMS) (opens in a new tab)Dmand AI Professional Profile Data
Practice locations and phoneNPPES NPI Registry (CMS) (opens in a new tab)Dmand AI Practice Data
Primary practice, affiliations and health systemNPPES NPI Registry (CMS) (opens in a new tab)Dmand AI Practice DataDmand AI Affiliation Data
Medicare patients and the all-payer patient panelDmand AI Patient Panel DataMedicare Physician & Other Practitioners - by Provider (CMS) (opens in a new tab)
Part D prescribingMedicare Part D Prescribers - by Provider and Drug (CMS) (opens in a new tab)Medicare Part D Prescribers - by Provider (CMS) (opens in a new tab)
MIPS scores, telehealth, assignment and procedure percentilesDoctors and Clinicians National Downloadable File (CMS) (opens in a new tab)Doctors and Clinicians Utilization Data (CMS) (opens in a new tab)
Publications, topics and co-authorsPubMed (National Library of Medicine) (opens in a new tab)Dmand AI Research Linkage
Industry paymentsOpen Payments (CMS) (opens in a new tab)
EHR at each practice siteDmand AI Technology Install Data
Similar physiciansDmand AI Affiliation Data

Data last refreshed October 2026Report an inaccuracyRemove my information

FAQ

Frequently asked questions about Dr. Nicholas J. Zarkadis

Spotted something out of date? Email hello@dmand.ai and we will check the record. Contact details live in the free trial.

What is Dr. Nicholas J. Zarkadis' NPI number?

Dr. Nicholas J. Zarkadis' NPI number is 1033558259. It was assigned on June 20, 2013, and it is active in the NPI Registry.

What kind of doctor is Dr. Nicholas J. Zarkadis?

Dr. Nicholas J. Zarkadis is an orthopedic surgeon in Saint Peters, Missouri. The primary specialty in the NPI Registry is Orthopaedic Surgery Physician (taxonomy code 207X00000X).

Where does Dr. Nicholas J. Zarkadis practice?

Dr. Zarkadis practices at 114 Piper Hill Dr, Saint Peters, MO 63376. Dr. Zarkadis' primary practice is St Peters Ambulatory Surgery Center in Saint Peters, Missouri. Dmand AI also links Dr. Zarkadis to 4 hospitals, 2 group practices and clinics and 1 medical group.

What is Dr. Nicholas J. Zarkadis' office phone number?

The practice phone on file for Dr. Zarkadis is (636) 928-1670.

What is Dr. Nicholas J. Zarkadis' medical license number?

Dr. Zarkadis holds Missouri license 2019016580, one of the licenses on file in 2 states.

Which states has Dr. Nicholas J. Zarkadis been licensed in?

Dmand AI has state licenses on file for Dr. Zarkadis in Missouri and Nebraska.

Which hospitals is Dr. Nicholas J. Zarkadis affiliated with?

Dr. Zarkadis is affiliated with Barnes-Jewish St. Peters Hospital. Dmand AI links Dr. Zarkadis to 4 more hospitals.

What medical group is Dr. Nicholas J. Zarkadis part of?

Dr. Zarkadis is linked to Advanced Bone & Joint. Dmand AI links Dr. Zarkadis to 1 more medical group.

Does Dr. Nicholas J. Zarkadis accept Medicare?

Yes. CMS lists Dr. Zarkadis as accepting Medicare assignment.

How many Medicare patients does Dr. Nicholas J. Zarkadis see?

CMS counts 73 Medicare patients who saw Dr. Zarkadis in 2024, with an average age of 75.

Show 5 more questionsShow fewer questions

What drugs does Dr. Nicholas J. Zarkadis prescribe most?

In 2024 Medicare Part D data, Dr. Zarkadis' most prescribed drugs by claims were Oxycodone HCl, Pantoprazole Sodium and Tramadol HCl.

Has Dr. Nicholas J. Zarkadis received payments from drug or device companies?

CMS Open Payments shows $26,694 in general payments to Dr. Zarkadis from 11 companies from 2017 to 2025. The largest total came from Smith & Nephew, Inc.

How long has Dr. Nicholas J. Zarkadis been practicing?

Dr. Zarkadis graduated from medical school in 2013, 13 years ago.

Does Dr. Nicholas J. Zarkadis do research?

Dmand AI links 12 publications to Dr. Zarkadis, published from 2013 to 2024.

Who does Dr. Nicholas J. Zarkadis publish with?

Dr. Zarkadis' most frequent co-authors are Nicholas Anthony Kusnezov, MD (6 shared papers), Mark Peter Pallis, DO (3 shared papers) and Gautham Sivaraj Prabhakar, MD (3 shared papers).

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