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Dr. Ernesto Ayala, MD
- Medicare services, 2024
- 89,822
- Medicare patients, 2024
- 850
- Part D claims, 2024
- 185
- Publications
- 120
- Clinical trials
- 8
- Practice address
- 4500 San Pablo Rd, Jacksonville, FL 32224
- Practice phone
- Call (904) 953-2000
- Professional email
- Get professional email
- Personal email
- Get personal email
- Mobile number
- Get mobile number
Primary practice
Find Dr. Ayala's professional email, personal email and mobile number
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Dr. Ernesto Ayala is a hematology (internal medicine) physician in Jacksonville, Florida
Dr. Ayala practices at Mayo Clinic Hospital in Jacksonville, Florida, part of Mayo Clinic.
Dr. Ayala's NPI, 1336164342, was assigned on July 12, 2006. Dr. Ayala graduated from National University of Colombia in 1985. Dr. Ayala holds Florida license ME91213.
- NPI
- 1336164342NPI Registry (opens in a new tab)
- Medicare PAC ID
- 8527029495
- NPI enumeration date
- July 12, 2006
- NPI status
- Active
- Accepts Medicare assignment
- Yes
- Offers telehealth
- Yes
- Practice phone
- (904) 953-2000
- Professional email
- Get email
- Personal email
- Get email
- Mobile number
- Get number
- Sex
- Male
- Estimated age
- 67
- Medical school graduation
- 1985
Sources: NPPES NPI Registry (CMS); Dmand AI Professional Profile Data; Dmand AI Affiliation Data; and Doctors and Clinicians National Downloadable File (CMS)
Dr. Ernesto Ayala practices at Mayo Clinic Hospital in Jacksonville, Florida
Dr. Ayala's primary practice is Mayo Clinic Hospital, at 4500 San Pablo Rd, Jacksonville, FL 32224 in Duval County. The practice phone is (904) 953-2000.
- Mayo Clinic Hospital4500 San Pablo Rd, Jacksonville, FL 32224 · Duval CountyPhone(904) 953-2000
Source: Dmand AI Affiliation Data
Dr. Ernesto Ayala is affiliated with 2 sites of care and 1 medical group
Dr. Ayala's primary practice is Mayo Clinic Hospital in Jacksonville, Florida, part of Mayo Clinic. Dr. Ayala is also affiliated with AdventHealth Daytona Beach. The medical group on file is Mayo Clinic Jacksonville.
Sources: Dmand AI Affiliation Data; and Dmand AI Org Hierarchy Data
Dmand AI tracks the EHR system at Dr. Ernesto Ayala's practice
Dmand AI tracks the electronic health record (EHR) system at each site where Dr. Ayala practices, 2 sites in all. Vendor and product names are available with a free account.
| Site | EHR vendor and product |
|---|---|
| Mayo Clinic Hospital | Available with a free account |
| +1 more affiliated site | Available with a free account |
Source: Dmand AI Technology Install Data
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Dr. Ernesto Ayala is one of 61 hematology (internal medicine) physicians in Florida
Internal medicine is Dr. Ayala's primary specialty in the NPI Registry, under taxonomy code 207RH0000X. The record also lists hematology. Dr. Ayala is board certified in hematology by the American Board of Internal Medicine. Dr. Ayala is licensed in Florida.
Specialties and state licenses
- Hematology (internal medicine), FloridaPrimary
Clinical focus
Dmand AI lists chronic leukemia, lymphoma and multiple myeloma among the conditions Dr. Ayala treats.
Hematology (internal medicine) physicians near Dr. Ayala
Counts of hematology (internal medicine) physicians with a Dmand AI profile, by place and practice. Each opens the list.
Sources: NPPES NPI Registry (CMS); Dmand AI Professional Profile Data; and Dmand AI Peer Benchmarks
Dr. Ernesto Ayala billed Medicare for 89,822 services in 2024
CMS data shows 89,822 Medicare services from Dr. Ayala across 60 procedure codes in 2024, for 850 Medicare patients. Medicare paid $1,385,138 for them.
Dr. Ayala's Medicare services by type, 2023 to 2024
- 2023
- 2024
- Drugs given in the office
- 2023: 84,8832024: 69,20018%
- Other services
- 2023: 22,2682024: 17,90920%
- Tests and treatments
- 2023: 2,0792024: 1,9785%
- Office and hospital visits
- 2023: 6192024: 54212%
- Surgery
- 2023: 2142024: 19310%
Where Dr. Ayala's Medicare services took place, 2024
- In an office89,601100%
- In a facility2210%
Dr. Ayala compared with the Florida median for hematology (internal medicine) physicians, 2024
- Dr. Ayala
- Florida median
- Medicare services
- 89,822vs 351255.9 times
- Medicare patients
- 850vs 1028.3 times
- Part D claims
- 78vs 25870% below
Medians across 56 hematology (internal medicine) physicians in Florida with Dmand AI profiles that report each measure.
Dr. Ayala's most billed Medicare procedure codes, 2024
CMS publishes codes billed for 11 or more Medicare patients. Each label is the code family; CPT descriptions are licensed by the AMA.
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Medicare shows one payer. Book a meeting to get commercial claims data for Dr. Ayala and other hematology (internal medicine) physicians in Florida.
Sources: Medicare Physician & Other Practitioners - by Provider and Service (CMS), 2024 data; and Dmand AI Peer Benchmarks
Dr. Ernesto Ayala treated 850 Medicare patients in 2024, average age 73
CMS counts 850 Medicare patients who saw Dr. Ayala in 2024. The largest group is 65 to 74, with 414 patients. 72% of them have high blood pressure, and 72% have high cholesterol. 4% are also on Medicaid. Their average risk score is 2.70, where 1.00 is the Medicare average, so they are sicker than most Medicare patients.
Across all payers, Dmand AI patient panel data puts Dr. Ayala's median patient age at 64, with 47% women.
Dr. Ayala's Medicare patients by age, 2024
Dr. Ayala's Medicare patients by sex, 2024
- Women40948%
- Men44152%
Chronic conditions among Dr. Ayala's Medicare patients, 2024
- High blood pressure72%
- High cholesterol72%
- Cancer49%
- Arthritis41%
- Chronic kidney disease35%
- Ischemic heart disease32%
- Anxiety28%
- Diabetes27%
Share of Medicare patients with each condition. A patient can have several.
Dr. Ayala's patients across all payers
Dmand AI patient panel data covers Medicare, Medicaid and commercial patients.
Patient panel by age, all payers
Median age 64
Patient panel by sex, all payers
- Women47%
- Men53%
Sources: Dmand AI Patient Panel Data; and Medicare Physician & Other Practitioners - by Provider (CMS), 2024 data
Dr. Ernesto Ayala wrote 185 Medicare Part D claims in 2024
In 2024, Dr. Ayala wrote 185 Medicare Part D claims for 33 patients. 83% of them were for generic drugs. CMS names the drug for 78 of them, across 4 drugs with 11 or more claims each, at $155,975 in total drug cost. In 2023, CMS named 76 claims across 4 drugs.
Dr. Ayala's Part D claims by kind of drug, 2024
- Generic153 claims83%
- Brand-name32 claims17%
Dr. Ayala's most prescribed drugs by claims, 2024
CMS names a drug when it has 11 or more claims. Share is of the claims for drugs CMS names.
Drug classes CMS tracks in Dr. Ayala's Part D claims, 2024
- Antibiotics16%29 of 185 claims
Share of all Part D claims for each drug class CMS reports on. Classes with no claims are left out.
Part D claims for drugs CMS names, 2023 to 2024
- 2023
- 2024
- Claims for drugs CMS names
- 2023: 762024: 783%
Drugs named by CMS: 4 in 2024, 4 in 2023.
Sources: Medicare Part D Prescribers - by Provider and Drug (CMS), 2024 data, released May 6, 2026; and Medicare Part D Prescribers - by Provider (CMS), 2024 data
Dr. Ernesto Ayala scored 84 out of 100 in Medicare's MIPS program for 2024
CMS publishes a Merit-based Incentive Payment System (MIPS) score of 84 out of 100 for Dr. Ayala for performance year 2024, reported as part of a group. Dr. Ayala accepts Medicare assignment, so Medicare's approved amount is taken as full payment. CMS lists Dr. Ayala as offering telehealth.
- Accepts Medicare assignment
- Yes
- Offers telehealth
- Yes
Dr. Ayala's MIPS scores, performance year 2024
- 84of 100Final score
- 74.8of 100Quality
- 100of 100Promoting Interoperability
- 40of 100Improvement Activities
- 73of 100Cost
Each score is out of 100. The final score weighs the categories CMS scored for this clinician.
Sources: Doctors and Clinicians National Downloadable File (CMS); and Clinician Public Reporting: Overall MIPS Performance (CMS), 2024 data, released September 10, 2026
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Dr. Ernesto Ayala has 120 publications on record
Dmand AI links 120 papers to Dr. Ayala, published from 2006 to 2025. 2020 was the busiest year, with 11. The most frequent topics are Hematopoietic Stem Cell Transplantation, Transplantation, Homologous and Graft vs Host Disease. Dr. Ayala has published most often in Bone Marrow Transplant. Dr. Ayala's most frequent co-authors are Claudio Anasetti, MD, Taiga Nishihori, MD and Lia E. Perez, MD.
Dr. Ayala's papers by year, 2016 to 2025
Topics Dr. Ayala writes about most
- Hematopoietic Stem Cell Transplantation
- Transplantation, Homologous
- Graft vs Host Disease
- Transplantation Conditioning
- Immunotherapy, Adoptive
- Immunosuppressive Agents
- Transplantation, Autologous
- Hematologic Neoplasms
Dr. Ayala's most frequent co-authors
- Claudio Anasetti, MD35 shared papers
- Taiga Nishihori, MD33 shared papers
- Lia E. Perez, MD30 shared papers
Recent publications by Dr. Ayala
Bone Marrow Transplant
See who Dr. Ayala researches with
Physician Network Discovery turns co-authorship, shared hospitals and shared groups into a map of who Dr. Ayala works with, so you can find a warm path to the right hematology (internal medicine) physicians.
Sources: PubMed (National Library of Medicine); and Dmand AI Research Linkage
Dr. Ernesto Ayala has worked on 8 clinical trials
Dmand AI links Dr. Ayala to 8 clinical trials, 3 of them phase 2 studies. Conditions studied include Bronchiolitis Obliterans Syndrome, Graft vs Host Disease and Immune System Diseases. H. Lee Moffitt Cancer Center and Research Institute sponsors the most, 6.
Clinical trials with Dr. Ayala by phase
- 2Phase 1: 2 trials
- 2Phase 1/2: 2 trials
- 3Phase 2: 3 trials
- 1Phase 3: 1 trial
- NonePhase 4: no trials
Conditions in Dr. Ayala's trials
- Bronchiolitis Obliterans Syndrome
- Graft vs Host Disease
- Immune System Diseases
- Organizing Pneumonia
- Leukemia, Myelomonocytic, Chronic
Investigators on the most trials with Dr. Ayala
- Melissa Alsina, MD5 shared trials
- Claudio Anasetti, MD5 shared trials
- Hugo Francisco Fernandez, MD5 shared trials
Recent clinical trials with Dr. Ayala
Calcineurin Inhibitor-Free GVHD Prevention Regimen After Related Haplo PBSCT (opens in a new tab)
Ex-vivo Expanded Donor Regulatory T Cells for Prevention of Acute Graft-Versus-Host Disease (opens in a new tab)
In Vivo Treg Expansion and Graft-Versus-Host Disease Prophylaxis (opens in a new tab)
Ofatumumab as Primary Therapy of Chronic Graft Versus Host Disease (opens in a new tab)
Sources: Dmand AI Research Linkage; and ClinicalTrials.gov (National Library of Medicine)
Dr. Ernesto Ayala received $850 in industry payments from 2016 to 2025
CMS Open Payments shows 15 general payments to Dr. Ayala from 8 drug and device companies from 2016 to 2025. Food and beverage make up the largest share, 99% of the total. Seagen Inc. paid the most, $486.
General payments to Dr. Ayala by program year, 2016 to 2025
General payments to Dr. Ayala by kind, 2016 to 2025
- Food and beverage$83899%
- Education$121%
Companies that paid Dr. Ayala the most, 2016 to 2025
Share is of all general payments to this clinician.
Source: Open Payments (CMS), 2025 data, released July 7, 2026
Dr. Ernesto Ayala graduated from National University of Colombia
Dr. Ayala graduated from National University of Colombia in 1985. Dr. Ayala is a member of ASCO and ASH.
- Medical school
- Board certified in hematology
- Board certified in internal medicine
- Board certified in medical oncology
Source: Dmand AI Professional Profile Data
Dr. Ernesto Ayala accepts plans from 6 insurance carriers
Dr. Ayala is in network with 6 carriers, including United Healthcare, Aspirus Health Plan and Blue Cross and Blue Shield of Kansas City. Medicare plans come from the most carriers, 2. Check the plan with the practice before a visit.
- United Healthcare
- Aspirus Health Plan
- Blue Cross and Blue Shield of Kansas City
- CMS Medicare
- Elevance
- HCSC
Plan types Dr. Ayala accepts, by number of carriers
- Medicare2
- POS2
- PPO2
- EPO1
- HMO1
Source: Dmand AI Insurance Network Data
Sources for Dr. Ernesto Ayala's profile data
| Data on this page | Source |
|---|---|
| NPI, name, sex, specialty and licenses | NPPES NPI Registry (CMS) (opens in a new tab)Dmand AI Professional Profile Data |
| Practice locations and phone | Dmand AI Affiliation Data |
| Primary practice, affiliations and health system | Dmand AI Affiliation DataDmand AI Org Hierarchy Data |
| Medicare services and procedure codes | Medicare Physician & Other Practitioners - by Provider and Service (CMS) (opens in a new tab) |
| State medians for the same specialty | Dmand AI Peer Benchmarks |
| Medicare patients and the all-payer patient panel | Dmand AI Patient Panel DataMedicare Physician & Other Practitioners - by Provider (CMS) (opens in a new tab) |
| Part D prescribing | Medicare Part D Prescribers - by Provider and Drug (CMS) (opens in a new tab)Medicare Part D Prescribers - by Provider (CMS) (opens in a new tab) |
| MIPS scores, telehealth, assignment and procedure percentiles | Doctors and Clinicians National Downloadable File (CMS) (opens in a new tab)Clinician Public Reporting: Overall MIPS Performance (CMS) (opens in a new tab) |
| Publications, topics and co-authors | PubMed (National Library of Medicine) (opens in a new tab)Dmand AI Research Linkage |
| Clinical trials and co-investigators | Dmand AI Research LinkageClinicalTrials.gov (National Library of Medicine) (opens in a new tab) |
| Industry payments | Open Payments (CMS) (opens in a new tab) |
| Training, board certification and memberships | Dmand AI Professional Profile Data |
| Insurance carriers and plan types | Dmand AI Insurance Network Data |
| EHR at each practice site | Dmand AI Technology Install Data |
| Similar physicians | Dmand AI Affiliation Data |
Data last refreshed October 2026Report an inaccuracyRemove my information
FAQ
Frequently asked questions about Dr. Ernesto Ayala
Spotted something out of date? Email hello@dmand.ai and we will check the record. Contact details live in the free trial.
What is Dr. Ernesto Ayala's NPI number?
Dr. Ernesto Ayala's NPI number is 1336164342. It was assigned on July 12, 2006, and it is active in the NPI Registry.
What kind of doctor is Dr. Ernesto Ayala?
Dr. Ernesto Ayala is a hematology (internal medicine) physician in Jacksonville, Florida. The primary specialty in the NPI Registry is Hematology (Internal Medicine) Physician (taxonomy code 207RH0000X).
Where does Dr. Ernesto Ayala practice?
Dr. Ayala practices at 4500 San Pablo Rd, Jacksonville, FL 32224. Dr. Ayala's primary practice is Mayo Clinic Hospital in Jacksonville, Florida, part of Mayo Clinic.
What is Dr. Ernesto Ayala's office phone number?
The practice phone on file for Dr. Ayala is (904) 953-2000.
What is Dr. Ernesto Ayala's medical license number?
Dr. Ayala holds Florida license ME91213.
Which hospitals is Dr. Ernesto Ayala affiliated with?
Dr. Ayala practices at Mayo Clinic Hospital in Jacksonville, Florida. Dr. Ayala is also affiliated with AdventHealth Daytona Beach.
What medical group is Dr. Ernesto Ayala part of?
Dr. Ayala is linked to Mayo Clinic Jacksonville.
Does Dr. Ernesto Ayala accept Medicare?
Yes. CMS data shows Dr. Ayala billed Medicare for 89,822 services in 2024, and Dr. Ayala accepts Medicare assignment.
Does Dr. Ernesto Ayala offer telehealth?
Yes. The CMS Doctors and Clinicians file lists Dr. Ayala as offering telehealth services.
What is Dr. Ernesto Ayala's MIPS score?
Dr. Ayala's MIPS final score for performance year 2024 is 84 out of 100, reported as part of a group.
Show 10 more questionsShow fewer questions
How many Medicare patients does Dr. Ernesto Ayala see?
CMS counts 850 Medicare patients who saw Dr. Ayala in 2024, with an average age of 73.
Is Dr. Ernesto Ayala board certified?
Yes. Dr. Ayala is board certified in hematology by the American Board of Internal Medicine.
What services does Dr. Ernesto Ayala bill to Medicare?
In 2024, Dr. Ayala's most billed Medicare services were injected or infused drug (J9271), medicare temporary code (Q5110) and injected or infused drug (J1453).
Where did Dr. Ernesto Ayala go to medical school?
Dr. Ayala graduated from National University of Colombia in 1985.
What drugs does Dr. Ernesto Ayala prescribe most?
In 2024 Medicare Part D data, Dr. Ayala's most prescribed drugs by claims were Acyclovir, Sulfamethoxazole-Trimethoprim and Amlodipine Besylate.
Has Dr. Ernesto Ayala received payments from drug or device companies?
CMS Open Payments shows $850 in general payments to Dr. Ayala from 8 companies from 2016 to 2025. The largest total came from Seagen Inc.
How long has Dr. Ernesto Ayala been practicing?
Dr. Ayala graduated from medical school in 1985, 41 years ago.
Does Dr. Ernesto Ayala do research?
Dmand AI links 120 publications to Dr. Ayala, published from 2006 to 2025. Dr. Ayala has worked on 8 clinical trials.
Who does Dr. Ernesto Ayala publish with?
Dr. Ayala's most frequent co-authors are Claudio Anasetti, MD (35 shared papers), Taiga Nishihori, MD (33 shared papers) and Lia E. Perez, MD (30 shared papers).
What insurance does Dr. Ernesto Ayala accept?
Dr. Ayala is in network with 6 carriers, including United Healthcare, Aspirus Health Plan and Blue Cross and Blue Shield of Kansas City. Medicare plans come from the most carriers, 2. Check the plan with the practice before a visit.
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