Dr. John O'Brien Clarke III, MD

  • Stanford, CA
  • Gastroenterologist
NPI1467539643PAC ID2264523398
Medicare services, 2024
1,377
Medicare patients, 2024
593
Part D claims, 2024
901
Publications
142
MIPS score, 2024
89
Practice address
300 Pasteur Drive, Stanford, CA 94305
Practice phone
Call (650) 723-4000
Professional email
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Personal email
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Mobile number
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Social profiles

Primary practice

Stanford Hospital at 300 Pasteur Drive

Hospital · Stanford, California

See all 4 affiliations

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Dr. John O'Brien Clarke III is a gastroenterologist in Stanford, California

Dr. Clarke practices at Stanford Hospital at 300 Pasteur Drive in Stanford, California, part of Stanford University.

Dr. Clarke's NPI, 1467539643, was assigned on November 1, 2006. Dr. Clarke graduated from Vagelos College of Physicians and Surgeons in 1999. Dr. Clarke holds California license C143081.

NPI and contact details
Medicare PAC ID
2264523398
NPI enumeration date
November 1, 2006
NPI status
Active
Accepts Medicare assignment
Yes
Offers telehealth
Yes
Practice phone
(650) 723-4000
Professional email
Get email
Personal email
Get email
Mobile number
Get number
Sex
Male
Estimated age
53
Medical school graduation
1999

Sources: NPPES NPI Registry (CMS); Dmand AI Professional Profile Data; Dmand AI Affiliation Data; and Doctors and Clinicians National Downloadable File (CMS)

Dr. John O'Brien Clarke III practices at Stanford Hospital at 300 Pasteur Drive in Stanford, California

Dr. Clarke's primary practice is Stanford Hospital at 300 Pasteur Drive, at 300 Pasteur Drive, Stanford, CA 94305 in Santa Clara County. The practice phone is (650) 723-4000.

Source: Dmand AI Affiliation Data

Dr. John O'Brien Clarke III is affiliated with 3 sites of care and 1 medical group

Dr. Clarke's primary practice is Stanford Hospital at 300 Pasteur Drive in Stanford, California, part of Stanford University. The medical group on file is Stanford Health Care. Dmand AI also links Dr. Clarke to 1 more hospital and 1 group practice or clinic, each named with a free account. Dr. Clarke's employer is on file too: a hospital.

See all 4 affiliations for Dr. Clarke

Sources: Dmand AI Affiliation Data; and Dmand AI Org Hierarchy Data

Dmand AI tracks the EHR system at Dr. John O'Brien Clarke III's practice

Dmand AI tracks the electronic health record (EHR) system at each site where Dr. Clarke practices, 3 sites in all. Vendor and product names are available with a free account.

EHR by site
SiteEHR vendor and product
Stanford Hospital at 300 Pasteur DriveAvailable with a free account
+2 more affiliated sitesAvailable with a free account

Source: Dmand AI Technology Install Data

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Dr. John O'Brien Clarke III is one of 1,977 gastroenterologists in California

Gastroenterology is Dr. Clarke's primary specialty in the NPI Registry, under taxonomy code 207RG0100X. Dr. Clarke is board certified in gastroenterology by the American Board of Internal Medicine. Dmand AI has Dr. Clarke's licenses on file in 2 states: California and Maryland.

Specialties and state licenses

  • Gastroenterology, CaliforniaPrimaryLicense C143081 · 2016 to 2026 · taxonomy 207RG0100X
  • Internal medicine, MarylandLicense D58832 · 2002 to 2016 · taxonomy 207R00000X

Clinical focus

Dmand AI lists acid reflux, acute stomach ulcer, colonoscopy, fatty liver, gastroenteritis, gastrointestinal bleeding, hemorrhoids and intestinal or bowel obstruction among the conditions Dr. Clarke treats.

Gastroenterologists near Dr. Clarke

Counts of gastroenterologists with a Dmand AI profile, by place and practice. Each opens the list.

Sources: NPPES NPI Registry (CMS); Dmand AI Professional Profile Data; and Dmand AI Peer Benchmarks

Dr. John O'Brien Clarke III billed Medicare for 1,377 services in 2024

CMS data shows 1,377 Medicare services from Dr. Clarke across 25 procedure codes in 2024, for 593 Medicare patients. Medicare paid $105,207 for them.

Medicare services, 20241,377
Medicare patients593
Paid by Medicare$105,207
Procedure codes25

Dr. Clarke's Medicare services by type, 2023 to 2024

  • 2023
  • 2024
Office and hospital visits
2023: 4142024: 49520%
Surgery
2023: 3512024: 39813%
Tests and treatments
2023: 3152024: 39726%
Other services
2023: 522024: 8767%

Where Dr. Clarke's Medicare services took place, 2024

  • In an office1,03875%
  • In a facility33925%

Dr. Clarke compared with the California median for gastroenterologists, 2024

  • Dr. Clarke
  • California median
Medicare services
1,377vs 5862.3 times
Medicare patients
593vs 30296% above
Part D claims
612vs 38061% above

Medians across 1,875 gastroenterologists in California with Dmand AI profiles that report each measure.

Dr. Clarke's most billed Medicare procedure codes, 2024

CMS publishes codes billed for 11 or more Medicare patients. Each label is the code family; CPT descriptions are licensed by the AMA.

See all procedures by Dr. Clarke

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Sources: Medicare Physician & Other Practitioners - by Provider and Service (CMS), 2024 data; and Dmand AI Peer Benchmarks

Dr. John O'Brien Clarke III treated 593 Medicare patients in 2024, average age 71

CMS counts 593 Medicare patients who saw Dr. Clarke in 2024. The largest group is 65 to 74, with 265 patients. 72% of them have high cholesterol, and 65% have high blood pressure. 23% are also on Medicaid. Their average risk score is 1.80, where 1.00 is the Medicare average, so they are sicker than most Medicare patients.

Across all payers, Dmand AI patient panel data puts Dr. Clarke's median patient age at 54, with 60% women.

Medicare patients, 2024593
Average age71
Average risk score1.80
Also on Medicaid23%

Dr. Clarke's Medicare patients by age, 2024

Dr. Clarke's Medicare patients by sex, 2024

  • Women36461%
  • Men22939%

Chronic conditions among Dr. Clarke's Medicare patients, 2024

  1. High cholesterol72%
  2. High blood pressure65%
  3. Arthritis44%
  4. Anxiety34%
  5. Mood disorders34%
  6. Depression30%
  7. Ischemic heart disease29%
  8. Osteoporosis29%

Share of Medicare patients with each condition. A patient can have several.

Dr. Clarke's patients across all payers

Dmand AI patient panel data covers Medicare, Medicaid and commercial patients.

Patient panel by age, all payers

Median age 54

Patient panel by sex, all payers

  • Women60%
  • Men37%

Sources: Dmand AI Patient Panel Data; and Medicare Physician & Other Practitioners - by Provider (CMS), 2024 data

Dr. John O'Brien Clarke III wrote 901 Medicare Part D claims in 2024

In 2024, Dr. Clarke wrote 901 Medicare Part D claims for 244 patients. 75% of them were for generic drugs. CMS names the drug for 612 of them, across 17 drugs with 11 or more claims each, at $224,731 in total drug cost. In 2023, CMS named 560 claims across 16 drugs.

Part D claims, 2024901
Drugs named by CMS17
Total drug cost$224,731
Part D patients244

Dr. Clarke's Part D claims by kind of drug, 2024

  • Generic672 claims75%
  • Brand-name and other229 claims25%

Dr. Clarke's most prescribed drugs by claims, 2024

CMS names a drug when it has 11 or more claims. Share is of the claims for drugs CMS names.

Drug classes CMS tracks in Dr. Clarke's Part D claims, 2024

  • Antibiotics7%62 of 901 claims

Share of all Part D claims for each drug class CMS reports on. Classes with no claims are left out.

Part D claims for drugs CMS names, 2023 to 2024

  • 2023
  • 2024
Claims for drugs CMS names
2023: 5602024: 6129%

Drugs named by CMS: 17 in 2024, 16 in 2023.

See all prescribing by Dr. Clarke

Sources: Medicare Part D Prescribers - by Provider and Drug (CMS), 2024 data, released May 6, 2026; and Medicare Part D Prescribers - by Provider (CMS), 2024 data

Dr. John O'Brien Clarke III scored 89 out of 100 in Medicare's MIPS program for 2024

CMS publishes a Merit-based Incentive Payment System (MIPS) score of 89 out of 100 for Dr. Clarke for performance year 2024, reported as part of a group. Dr. Clarke accepts Medicare assignment, so Medicare's approved amount is taken as full payment. CMS lists Dr. Clarke as offering telehealth. CMS counts 317 procedures of upper gastrointestinal (gi) endoscopy for acid reflux by Dr. Clarke, more than 96% of the clinicians it reports for that procedure.

Accepts Medicare assignment
Yes
Offers telehealth
Yes

Dr. Clarke's MIPS scores, performance year 2024

  • 89of 100Final score
  • 87.1of 100Quality
  • 100of 100Promoting Interoperability
  • 40of 100Improvement Activities
  • 70of 100Cost

Each score is out of 100. The final score weighs the categories CMS scored for this clinician.

Where Dr. Clarke ranks in Medicare procedure volume

Upper gastrointestinal (GI) endoscopy for acid reflux
96th percentile317 procedures
Colonoscopy
66th percentile56 procedures

CMS ranks each clinician against every clinician it reports for the same procedure category.

Sources: Doctors and Clinicians National Downloadable File (CMS); Clinician Public Reporting: Overall MIPS Performance (CMS), 2024 data, released September 10, 2026; and Doctors and Clinicians Utilization Data (CMS)

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Dr. John O'Brien Clarke III has 142 publications on record

Dmand AI links 142 papers to Dr. Clarke, published from 2007 to 2025. 2020 was the busiest year, with 15. The most frequent topics are Gastroesophageal Reflux, Manometry and Esophageal Achalasia. Dr. Clarke has published most often in Neurogastroenterol Motil. Dr. Clarke's most frequent co-authors are George Triadafilopoulos, MD, Thomas Antonios Zikos, MD and Jonathan Michael Buscaglia, MD.

Papers142
Years published2007 to 2025

Dr. Clarke's papers by year, 2016 to 2025

Topics Dr. Clarke writes about most

  • Gastroesophageal Reflux
  • Manometry
  • Esophageal Achalasia
  • Esophageal pH Monitoring
  • Esophagogastric Junction
  • Gastroparesis
  • Electric Impedance
  • Esophagoscopy

Dr. Clarke's most frequent co-authors

Recent publications by Dr. Clarke

See all 142 publications and co-authors

See who Dr. Clarke researches with

Physician Network Discovery turns co-authorship, shared hospitals and shared groups into a map of who Dr. Clarke works with, so you can find a warm path to the right gastroenterologists.

How network discovery works

Sources: PubMed (National Library of Medicine); and Dmand AI Research Linkage

Dr. John O'Brien Clarke III received $29,869 in industry payments from 2016 to 2025

CMS Open Payments shows 34 general payments to Dr. Clarke from 15 drug and device companies from 2016 to 2025. Consulting fees make up the largest share, 60% of the total. Sanofi and Genzyme US Companies paid the most, $15,561. It also lists 8 research payments totaling $10,497 from 2017 to 2025.

General payments to Dr. Clarke by program year, 2016 to 2025

General payments to Dr. Clarke by kind, 2016 to 2025

$29.9Kin total
  • Consulting fees$18,00260%
  • Honoraria$8,50028%
  • Food and beverage$1,9106%
  • Travel and lodging$1,4585%

Companies that paid Dr. Clarke the most, 2016 to 2025

Share is of all general payments to this clinician.

See all payments to Dr. Clarke

Source: Open Payments (CMS), 2025 data, released July 7, 2026

Dr. John O'Brien Clarke III graduated from Vagelos College of Physicians and Surgeons

Dr. Clarke graduated from Vagelos College of Physicians and Surgeons in 1999.

  1. Medical schoolVagelos College of Physicians and Surgeons
  2. Board certified in gastroenterologyAmerican Board of Internal Medicine
  3. Board certified in internal medicineAmerican Board of Internal Medicine

Source: Dmand AI Professional Profile Data

Dr. John O'Brien Clarke III accepts plans from 11 insurance carriers

Dr. Clarke is in network with 11 carriers, including Aetna, Excellus BlueCross BlueShield and Blue Cross Blue Shield of Michigan. Medicare plans come from the most carriers, 8. Check the plan with the practice before a visit.

  • Aetna
  • Excellus BlueCross BlueShield
  • Blue Cross Blue Shield of Michigan
  • Elevance
  • Blue Cross Blue Shield of Massachusetts
  • HCSC
  • Regence Health Plans
  • United Healthcare
  • +3 more carriersWith a free account

Plan types Dr. Clarke accepts, by number of carriers

  1. Medicare8
  2. PPO7
  3. POS5
  4. EPO4
  5. HMO4
  6. Medicaid1

Source: Dmand AI Insurance Network Data

Sources for Dr. John O'Brien Clarke III's profile data

Sources for the data on this page
Data on this pageSource
NPI, name, sex, specialty and licensesNPPES NPI Registry (CMS) (opens in a new tab)Dmand AI Professional Profile Data
Practice locations and phoneDmand AI Affiliation Data
Primary practice, affiliations and health systemDmand AI Affiliation DataDmand AI Org Hierarchy Data
Medicare services and procedure codesMedicare Physician & Other Practitioners - by Provider and Service (CMS) (opens in a new tab)
State medians for the same specialtyDmand AI Peer Benchmarks
Medicare patients and the all-payer patient panelDmand AI Patient Panel DataMedicare Physician & Other Practitioners - by Provider (CMS) (opens in a new tab)
Part D prescribingMedicare Part D Prescribers - by Provider and Drug (CMS) (opens in a new tab)Medicare Part D Prescribers - by Provider (CMS) (opens in a new tab)
MIPS scores, telehealth, assignment and procedure percentilesDoctors and Clinicians National Downloadable File (CMS) (opens in a new tab)Clinician Public Reporting: Overall MIPS Performance (CMS) (opens in a new tab)Doctors and Clinicians Utilization Data (CMS) (opens in a new tab)
Publications, topics and co-authorsPubMed (National Library of Medicine) (opens in a new tab)Dmand AI Research Linkage
Industry paymentsOpen Payments (CMS) (opens in a new tab)
Training, board certification and membershipsDmand AI Professional Profile Data
Insurance carriers and plan typesDmand AI Insurance Network Data
EHR at each practice siteDmand AI Technology Install Data
Similar physiciansDmand AI Affiliation Data

Data last refreshed October 2026Report an inaccuracyRemove my information

FAQ

Frequently asked questions about Dr. John O'Brien Clarke III

Spotted something out of date? Email hello@dmand.ai and we will check the record. Contact details live in the free trial.

What is Dr. John O'Brien Clarke III's NPI number?

Dr. John O'Brien Clarke III's NPI number is 1467539643. It was assigned on November 1, 2006, and it is active in the NPI Registry.

What kind of doctor is Dr. John O'Brien Clarke III?

Dr. John O'Brien Clarke III is a gastroenterologist in Stanford, California. The primary specialty in the NPI Registry is Gastroenterology Physician (taxonomy code 207RG0100X).

Where does Dr. John O'Brien Clarke III practice?

Dr. Clarke practices at 300 Pasteur Drive, Stanford, CA 94305. Dr. Clarke's primary practice is Stanford Hospital at 300 Pasteur Drive in Stanford, California, part of Stanford University. Dmand AI also links Dr. Clarke to 1 hospital and 1 group practice or clinic.

What is Dr. John O'Brien Clarke III's office phone number?

The practice phone on file for Dr. Clarke is (650) 723-4000.

What is Dr. John O'Brien Clarke III's medical license number?

Dr. Clarke holds California license C143081, one of the licenses on file in 2 states.

Which states has Dr. John O'Brien Clarke III been licensed in?

Dmand AI has state licenses on file for Dr. Clarke in California (2016 to 2026) and Maryland (2002 to 2016).

Which hospitals is Dr. John O'Brien Clarke III affiliated with?

Dr. Clarke practices at Stanford Hospital at 300 Pasteur Drive in Stanford, California. Dmand AI links Dr. Clarke to 1 more hospital.

What medical group is Dr. John O'Brien Clarke III part of?

Dr. Clarke is linked to Stanford Health Care.

Does Dr. John O'Brien Clarke III accept Medicare?

Yes. CMS data shows Dr. Clarke billed Medicare for 1,377 services in 2024, and Dr. Clarke accepts Medicare assignment.

Does Dr. John O'Brien Clarke III offer telehealth?

Yes. The CMS Doctors and Clinicians file lists Dr. Clarke as offering telehealth services.

Show 11 more questionsShow fewer questions

What is Dr. John O'Brien Clarke III's MIPS score?

Dr. Clarke's MIPS final score for performance year 2024 is 89 out of 100, reported as part of a group.

How many Medicare patients does Dr. John O'Brien Clarke III see?

CMS counts 593 Medicare patients who saw Dr. Clarke in 2024, with an average age of 71.

Is Dr. John O'Brien Clarke III board certified?

Yes. Dr. Clarke is board certified in gastroenterology by the American Board of Internal Medicine.

What services does Dr. John O'Brien Clarke III bill to Medicare?

In 2024, Dr. Clarke's most billed Medicare services were office visit, established patient (99214), surgery: digestive system (43239) and digestive system test (91065).

Where did Dr. John O'Brien Clarke III go to medical school?

Dr. Clarke graduated from Vagelos College of Physicians and Surgeons in 1999.

What drugs does Dr. John O'Brien Clarke III prescribe most?

In 2024 Medicare Part D data, Dr. Clarke's most prescribed drugs by claims were Pantoprazole Sodium, Dexlansoprazole DR and Omeprazole.

Has Dr. John O'Brien Clarke III received payments from drug or device companies?

CMS Open Payments shows $29,869 in general payments to Dr. Clarke from 15 companies from 2016 to 2025. The largest total came from Sanofi and Genzyme US Companies.

How long has Dr. John O'Brien Clarke III been practicing?

Dr. Clarke graduated from medical school in 1999, 27 years ago.

Does Dr. John O'Brien Clarke III do research?

Dmand AI links 142 publications to Dr. Clarke, published from 2007 to 2025.

Who does Dr. John O'Brien Clarke III publish with?

Dr. Clarke's most frequent co-authors are George Triadafilopoulos, MD (32 shared papers), Thomas Antonios Zikos, MD (17 shared papers) and Jonathan Michael Buscaglia, MD (15 shared papers).

What insurance does Dr. John O'Brien Clarke III accept?

Dr. Clarke is in network with 11 carriers, including Aetna, Excellus BlueCross BlueShield and Blue Cross Blue Shield of Michigan. Medicare plans come from the most carriers, 8. Check the plan with the practice before a visit.

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