Dr. Constantine Tsigrelis, MD

  • Cleveland, OH
  • Infectious disease specialist
NPI1750369682PAC ID9931137460
Medicare services, 2024
571
Medicare patients, 2024
122
Part D claims, 2024
245
Publications
11
Hospital affiliations
4
Practice address
9500 Euclid Avenue, Cleveland, OH 44195
Practice phone
Call (216) 952-9829
Professional email
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Personal email
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Mobile number
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Social profiles

Primary practice

Cleveland Clinic Main Campus

Hospital · Cleveland, Ohio

See all 8 affiliations

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Dr. Constantine Tsigrelis is an infectious disease specialist in Cleveland, Ohio

Dr. Tsigrelis practices at Cleveland Clinic Main Campus in Cleveland, Ohio, part of The Cleveland Clinic Foundation.

Dr. Tsigrelis' NPI, 1750369682, was assigned on December 30, 2005. Dr. Tsigrelis graduated from Rutgers R W Johnson Medical School (Cam/New Bruns/Pisc) in 2002. Dr. Tsigrelis holds Ohio license 35-122767.

NPI and contact details
Medicare PAC ID
9931137460
NPI enumeration date
December 30, 2005
NPI status
Active
Accepts Medicare assignment
Yes
Offers telehealth
Yes
Practice phone
(216) 952-9829
Professional email
Get email
Personal email
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Mobile number
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Sex
Male
Estimated age
50
Medical school graduation
2002

Sources: NPPES NPI Registry (CMS); Dmand AI Professional Profile Data; Dmand AI Affiliation Data; and Doctors and Clinicians National Downloadable File (CMS)

Dr. Constantine Tsigrelis practices at Cleveland Clinic Main Campus in Cleveland, Ohio

Dr. Tsigrelis' primary practice is Cleveland Clinic Main Campus, at 9500 Euclid Avenue, Cleveland, OH 44195 in Cuyahoga County. The practice phone is (216) 952-9829.

Source: Dmand AI Affiliation Data

Dr. Constantine Tsigrelis is affiliated with 6 sites of care and 2 medical groups

Dr. Tsigrelis' primary practice is Cleveland Clinic Main Campus in Cleveland, Ohio, part of The Cleveland Clinic Foundation. Dr. Tsigrelis is also affiliated with University Hospitals Cleveland Medical Center. The medical group on file is Cleveland Clinic. Dmand AI also links Dr. Tsigrelis to 2 more hospitals, 2 clinical labs and 1 medical group, each named with a free account. Dr. Tsigrelis' employer is on file too: a hospital.

See all 8 affiliations for Dr. Tsigrelis

Sources: Dmand AI Affiliation Data; and Dmand AI Org Hierarchy Data

Dmand AI tracks the EHR system at Dr. Constantine Tsigrelis' practice

Dmand AI tracks the electronic health record (EHR) system at each site where Dr. Tsigrelis practices, 6 sites in all. Vendor and product names are available with a free account.

EHR by site
SiteEHR vendor and product
Cleveland Clinic Main CampusAvailable with a free account
+5 more sites and 1 medical groupAvailable with a free account

Source: Dmand AI Technology Install Data

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Dr. Constantine Tsigrelis is one of 319 infectious disease specialists in Ohio

Infectious disease is Dr. Tsigrelis' primary specialty in the NPI Registry, under taxonomy code 207RI0200X. Dmand AI has Dr. Tsigrelis' licenses on file in 3 states: Ohio, Minnesota and New Jersey.

Specialties and state licenses

  • Infectious disease, OhioPrimaryLicense 35-122767 · taxonomy 207RI0200X
  • Minnesota licenseLicense 48074
  • New Jersey licenseLicense MA07803400

Infectious disease specialists near Dr. Tsigrelis

Counts of infectious disease specialists with a Dmand AI profile, by place and practice. Each opens the list.

Sources: NPPES NPI Registry (CMS); Dmand AI Professional Profile Data; and Dmand AI Peer Benchmarks

Dr. Constantine Tsigrelis billed Medicare for 571 services in 2024

CMS data shows 571 Medicare services from Dr. Tsigrelis across 7 procedure codes in 2024, for 122 Medicare patients. Medicare paid $45,604 for them.

Medicare services, 2024571
Medicare patients122
Paid by Medicare$45,604
Procedure codes7

Dr. Tsigrelis' Medicare services by type, 2023 to 2024

  • 2023
  • 2024
Office and hospital visits
2023: 5632024: 5257%
Other services
2023: 492024: 466%

Where Dr. Tsigrelis' Medicare services took place, 2024

  • In an office12322%
  • In a facility44878%

Dr. Tsigrelis compared with the Ohio median for infectious disease specialists, 2024

  • Dr. Tsigrelis
  • Ohio median
Medicare services
571vs 36158% above
Medicare patients
122vs 14415% below
Part D claims
163vs 22026% below

Medians across 312 infectious disease specialists in Ohio with Dmand AI profiles that report each measure.

Dr. Tsigrelis' most billed Medicare procedure codes, 2024

CMS publishes codes billed for 11 or more Medicare patients. Each label is the code family; CPT descriptions are licensed by the AMA.

See all procedures by Dr. Tsigrelis

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Sources: Medicare Physician & Other Practitioners - by Provider and Service (CMS), 2024 data; and Dmand AI Peer Benchmarks

Dr. Constantine Tsigrelis treated 122 Medicare patients in 2024, average age 76

CMS counts 122 Medicare patients who saw Dr. Tsigrelis in 2024. The largest group is 75 to 84, with 58 patients. 75% of them have high blood pressure, and 75% have high cholesterol. 13% are also on Medicaid. Their average risk score is 2.90, where 1.00 is the Medicare average, so they are sicker than most Medicare patients.

Across all payers, Dmand AI patient panel data puts Dr. Tsigrelis' median patient age at 64, with 47% women.

Medicare patients, 2024122
Average age76
Average risk score2.90
Also on Medicaid13%

Dr. Tsigrelis' Medicare patients by age, 2024

Dr. Tsigrelis' Medicare patients by sex, 2024

  • Women5948%
  • Men6352%

Chronic conditions among Dr. Tsigrelis' Medicare patients, 2024

  1. High blood pressure75%
  2. High cholesterol75%
  3. Arthritis63%
  4. Chronic kidney disease59%
  5. Ischemic heart disease49%
  6. Atrial fibrillation45%
  7. Heart failure45%
  8. Anxiety44%

Share of Medicare patients with each condition. A patient can have several.

Dr. Tsigrelis' patients across all payers

Dmand AI patient panel data covers Medicare, Medicaid and commercial patients.

Patient panel by age, all payers

Median age 64

Patient panel by sex, all payers

  • Women47%
  • Men52%

Sources: Dmand AI Patient Panel Data; and Medicare Physician & Other Practitioners - by Provider (CMS), 2024 data

Dr. Constantine Tsigrelis wrote 245 Medicare Part D claims in 2024

In 2024, Dr. Tsigrelis wrote 245 Medicare Part D claims for 71 patients. 90% of them were for generic drugs. CMS names the drug for 163 of them, across 10 drugs with 11 or more claims each, at $12,800 in total drug cost. In 2023, CMS named 96 claims across 5 drugs.

Part D claims, 2024245
Drugs named by CMS10
Total drug cost$12,800
Part D patients71

Dr. Tsigrelis' Part D claims by kind of drug, 2024

  • Generic221 claims90%
  • Brand-name24 claims10%

Dr. Tsigrelis' most prescribed drugs by claims, 2024

CMS names a drug when it has 11 or more claims. Share is of the claims for drugs CMS names.

Drug classes CMS tracks in Dr. Tsigrelis' Part D claims, 2024

  • Antibiotics67%164 of 245 claims

Share of all Part D claims for each drug class CMS reports on. Classes with no claims are left out.

Part D claims for drugs CMS names, 2023 to 2024

  • 2023
  • 2024
Claims for drugs CMS names
2023: 962024: 16370%

Drugs named by CMS: 10 in 2024, 5 in 2023.

See all prescribing by Dr. Tsigrelis

Sources: Medicare Part D Prescribers - by Provider and Drug (CMS), 2024 data, released May 6, 2026; and Medicare Part D Prescribers - by Provider (CMS), 2024 data

Dr. Constantine Tsigrelis offers telehealth to Medicare patients

Dr. Tsigrelis accepts Medicare assignment, so Medicare's approved amount is taken as full payment. CMS lists Dr. Tsigrelis as offering telehealth.

Accepts Medicare assignment
Yes
Offers telehealth
Yes

Source: Doctors and Clinicians National Downloadable File (CMS)

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Dr. Constantine Tsigrelis has 11 publications on record

Dmand AI links 11 papers to Dr. Tsigrelis, published from 2011 to 2017. 2015 was the busiest year, with 3. The most frequent topics are Intensive Care Units, Anti-Bacterial Agents and Antibodies, Bacterial. Dr. Tsigrelis has published most often in Infect Dis (Lond). Dr. Tsigrelis' most frequent co-authors are Henry S. Fraimow, MD, Young J. Juhn, MD and Ziad C. Boujaoude, MD.

Papers11
Years published2011 to 2017

Dr. Tsigrelis' papers by year, 2011 to 2017

Topics Dr. Tsigrelis writes about most

  • Intensive Care Units
  • Anti-Bacterial Agents
  • Antibodies, Bacterial
  • Asthma
  • Enzyme-Linked Immunosorbent Assay
  • Interleukin-5
  • Pneumococcal Infections
  • Pneumococcal Vaccines

Dr. Tsigrelis' most frequent co-authors

Recent publications by Dr. Tsigrelis

See all 11 publications and co-authors

See who Dr. Tsigrelis researches with

Physician Network Discovery turns co-authorship, shared hospitals and shared groups into a map of who Dr. Tsigrelis works with, so you can find a warm path to the right infectious disease specialists.

How network discovery works

Sources: PubMed (National Library of Medicine); and Dmand AI Research Linkage

Dr. Constantine Tsigrelis received $87 in industry payments in 2019

CMS Open Payments shows 1 general payment to Dr. Tsigrelis from 1 drug or device company in 2019. Food and beverage make up the largest share, 100% of the total. Insmed, Inc. paid the most, $87.

Companies that paid Dr. Tsigrelis the most, 2019 to 2019

Share is of all general payments to this clinician.

See all payments to Dr. Tsigrelis

Source: Open Payments (CMS), 2025 data, released July 7, 2026

Dr. Constantine Tsigrelis graduated from Rutgers R W Johnson Medical School (Cam/New Bruns/Pisc)

Dr. Tsigrelis graduated from Rutgers R W Johnson Medical School (Cam/New Bruns/Pisc) in 2002.

  1. Medical schoolRutgers R W Johnson Medical School (Cam/New Bruns/Pisc)

Source: Dmand AI Professional Profile Data

Sources for Dr. Constantine Tsigrelis's profile data

Sources for the data on this page
Data on this pageSource
NPI, name, sex, specialty and licensesNPPES NPI Registry (CMS) (opens in a new tab)Dmand AI Professional Profile Data
Practice locations and phoneDmand AI Affiliation Data
Primary practice, affiliations and health systemDmand AI Affiliation DataDmand AI Org Hierarchy Data
Medicare services and procedure codesMedicare Physician & Other Practitioners - by Provider and Service (CMS) (opens in a new tab)
State medians for the same specialtyDmand AI Peer Benchmarks
Medicare patients and the all-payer patient panelDmand AI Patient Panel DataMedicare Physician & Other Practitioners - by Provider (CMS) (opens in a new tab)
Part D prescribingMedicare Part D Prescribers - by Provider and Drug (CMS) (opens in a new tab)Medicare Part D Prescribers - by Provider (CMS) (opens in a new tab)
MIPS scores, telehealth, assignment and procedure percentilesDoctors and Clinicians National Downloadable File (CMS) (opens in a new tab)
Publications, topics and co-authorsPubMed (National Library of Medicine) (opens in a new tab)Dmand AI Research Linkage
Industry paymentsOpen Payments (CMS) (opens in a new tab)
Training, board certification and membershipsDmand AI Professional Profile Data
EHR at each practice siteDmand AI Technology Install Data
Similar physiciansDmand AI Affiliation Data

Data last refreshed October 2026Report an inaccuracyRemove my information

FAQ

Frequently asked questions about Dr. Constantine Tsigrelis

Spotted something out of date? Email hello@dmand.ai and we will check the record. Contact details live in the free trial.

What is Dr. Constantine Tsigrelis' NPI number?

Dr. Constantine Tsigrelis' NPI number is 1750369682. It was assigned on December 30, 2005, and it is active in the NPI Registry.

What kind of doctor is Dr. Constantine Tsigrelis?

Dr. Constantine Tsigrelis is an infectious disease specialist in Cleveland, Ohio. The primary specialty in the NPI Registry is Infectious Disease Physician (taxonomy code 207RI0200X).

Where does Dr. Constantine Tsigrelis practice?

Dr. Tsigrelis practices at 9500 Euclid Avenue, Cleveland, OH 44195. Dr. Tsigrelis' primary practice is Cleveland Clinic Main Campus in Cleveland, Ohio, part of The Cleveland Clinic Foundation. Dmand AI also links Dr. Tsigrelis to 2 hospitals, 2 clinical labs and 1 medical group.

What is Dr. Constantine Tsigrelis' office phone number?

The practice phone on file for Dr. Tsigrelis is (216) 952-9829.

What is Dr. Constantine Tsigrelis' medical license number?

Dr. Tsigrelis holds Ohio license 35-122767, one of the licenses on file in 3 states.

Which states has Dr. Constantine Tsigrelis been licensed in?

Dmand AI has state licenses on file for Dr. Tsigrelis in Ohio, Minnesota and New Jersey.

Which hospitals is Dr. Constantine Tsigrelis affiliated with?

Dr. Tsigrelis practices at Cleveland Clinic Main Campus in Cleveland, Ohio. Dr. Tsigrelis is also affiliated with University Hospitals Cleveland Medical Center. Dmand AI links Dr. Tsigrelis to 2 more hospitals.

What medical group is Dr. Constantine Tsigrelis part of?

Dr. Tsigrelis is linked to Cleveland Clinic. Dmand AI links Dr. Tsigrelis to 1 more medical group.

Does Dr. Constantine Tsigrelis accept Medicare?

Yes. CMS data shows Dr. Tsigrelis billed Medicare for 571 services in 2024, and Dr. Tsigrelis accepts Medicare assignment.

Does Dr. Constantine Tsigrelis offer telehealth?

Yes. The CMS Doctors and Clinicians file lists Dr. Tsigrelis as offering telehealth services.

Show 8 more questionsShow fewer questions

How many Medicare patients does Dr. Constantine Tsigrelis see?

CMS counts 122 Medicare patients who saw Dr. Tsigrelis in 2024, with an average age of 76.

What services does Dr. Constantine Tsigrelis bill to Medicare?

In 2024, Dr. Tsigrelis' most billed Medicare services were hospital inpatient care (99233), hospital inpatient care (99232) and medicare service (G2212).

Where did Dr. Constantine Tsigrelis go to medical school?

Dr. Tsigrelis graduated from Rutgers R W Johnson Medical School (Cam/New Bruns/Pisc) in 2002.

What drugs does Dr. Constantine Tsigrelis prescribe most?

In 2024 Medicare Part D data, Dr. Tsigrelis' most prescribed drugs by claims were Amoxicillin, Cefadroxil and Rifampin.

Has Dr. Constantine Tsigrelis received payments from drug or device companies?

CMS Open Payments shows $87 in general payments to Dr. Tsigrelis from 1 company from 2019 to 2019. The largest total came from Insmed, Inc.

How long has Dr. Constantine Tsigrelis been practicing?

Dr. Tsigrelis graduated from medical school in 2002, 24 years ago.

Does Dr. Constantine Tsigrelis do research?

Dmand AI links 11 publications to Dr. Tsigrelis, published from 2011 to 2017.

Who does Dr. Constantine Tsigrelis publish with?

Dr. Tsigrelis' most frequent co-authors are Henry S. Fraimow, MD (3 shared papers), Young J. Juhn, MD (3 shared papers) and Ziad C. Boujaoude, MD (1 shared paper).

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