Ryan D. Knake, PA-C

  • Cape Coral, FL
  • Physician assistant
NPI1063805745PAC ID0244597730
Medicare services, 2024
1,680
Medicare patients, 2024
92
Part D claims, 2024
350
Hospital affiliations
3
Industry payments
$176
Practice address
636 Del Prado Blvd, Cape Coral, FL 33990
Practice phone
Call (239) 424-2000
Professional email
Get professional email
Personal email
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Mobile number
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Social profiles

Primary practice

Cape Coral Hospital

Hospital · Cape Coral, Florida

See all 5 affiliations

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Ryan D. Knake is a physician assistant in Cape Coral, Florida

Ryan Knake practices at Cape Coral Hospital in Cape Coral, Florida, part of Lee Health System.

Ryan Knake's NPI, 1063805745, was assigned on March 5, 2015. Ryan Knake holds Florida license PA9108558.

NPI and contact details
Medicare PAC ID
0244597730
NPI enumeration date
March 5, 2015
NPI status
Active
Accepts Medicare assignment
Yes
Practice phone
(239) 424-2000
Professional email
Get email
Personal email
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Mobile number
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Sex
Male
Estimated age
37
Medical school graduation
2015

Sources: NPPES NPI Registry (CMS); Dmand AI Professional Profile Data; Dmand AI Affiliation Data; and Doctors and Clinicians National Downloadable File (CMS)

Ryan D. Knake practices at Cape Coral Hospital in Cape Coral, Florida

Ryan Knake's primary practice is Cape Coral Hospital, at 636 Del Prado Blvd, Cape Coral, FL 33990 in Lee County. The practice phone is (239) 424-2000.

  • Cape Coral Hospital
    636 Del Prado Blvd, Cape Coral, FL 33990 · Lee CountyPhone(239) 424-2000

Source: Dmand AI Affiliation Data

Ryan D. Knake is affiliated with 4 sites of care and 1 medical group

Ryan Knake's primary practice is Cape Coral Hospital in Cape Coral, Florida, part of Lee Health System. Ryan Knake is also affiliated with Lee Memorial Hospital. The medical group on file is GenesisCare. Dmand AI also links Ryan Knake to 1 more hospital and 1 group practice or clinic, each named with a free account.

See all 5 affiliations for Ryan Knake

Sources: Dmand AI Affiliation Data; and Dmand AI Org Hierarchy Data

Dmand AI tracks the EHR system at Ryan D. Knake's practice

Dmand AI tracks the electronic health record (EHR) system at each site where Ryan Knake practices, 4 sites in all. Vendor and product names are available with a free account.

EHR by site
SiteEHR vendor and product
Cape Coral HospitalAvailable with a free account
+3 more affiliated sitesAvailable with a free account

Source: Dmand AI Technology Install Data

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Ryan D. Knake is one of 7,899 physician assistants in Florida

Physician assistant is Ryan Knake's primary specialty in the NPI Registry, under taxonomy code 363A00000X. Ryan Knake is board certified in certified physician assistant by the National Commission on Certification of Physician Assistants (NCCPA). Ryan Knake is licensed in Florida.

Specialties and state licenses

  • Physician assistant, FloridaPrimaryLicense PA9108558 · taxonomy 363A00000X

Physician assistants near Ryan Knake

Counts of physician assistants with a Dmand AI profile, by place and practice. Each opens the list.

Sources: NPPES NPI Registry (CMS); Dmand AI Professional Profile Data; and Dmand AI Peer Benchmarks

Ryan D. Knake billed Medicare for 1,680 services in 2024

CMS data shows 1,680 Medicare services from Ryan Knake across 4 procedure codes in 2024, for 92 Medicare patients. Medicare paid $64,455 for them. Every service was in a facility, such as a hospital, rather than an office.

Medicare services, 20241,680
Medicare patients92
Paid by Medicare$64,455
Procedure codes4

Ryan Knake compared with the Florida median for physician assistants, 2024

  • Ryan Knake
  • Florida median
Medicare services
1,680vs 3215.2 times
Medicare patients
92vs 13029% below
Part D claims
211vs 32635% below

Medians across 5,430 physician assistants in Florida with Dmand AI profiles that report each measure.

Ryan Knake's most billed Medicare procedure codes, 2024

CMS publishes codes billed for 11 or more Medicare patients. Each label is the code family; CPT descriptions are licensed by the AMA.

See all procedures by Ryan Knake

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Sources: Medicare Physician & Other Practitioners - by Provider and Service (CMS), 2024 data; and Dmand AI Peer Benchmarks

Ryan D. Knake treated 92 Medicare patients in 2024, average age 76

CMS counts 92 Medicare patients who saw Ryan Knake in 2024. The largest group is 65 to 74, with 33 patients. 75% of them have high blood pressure, and 75% have high cholesterol. 21% are also on Medicaid. Their average risk score is 3.52, where 1.00 is the Medicare average, so they are sicker than most Medicare patients.

Across all payers, Dmand AI patient panel data puts Ryan Knake's median patient age at 70, with 33% women.

Medicare patients, 202492
Average age76
Average risk score3.52
Also on Medicaid21%

Ryan Knake's Medicare patients by age, 2024

CMS leaves out age groups with fewer than 11 patients.

Ryan Knake's Medicare patients by sex, 2024

  • Women3235%
  • Men6065%

Chronic conditions among Ryan Knake's Medicare patients, 2024

  1. High blood pressure75%
  2. High cholesterol75%
  3. Heart failure72%
  4. Mood disorders63%
  5. Chronic kidney disease62%
  6. Diabetes60%
  7. Atrial fibrillation59%
  8. Arthritis58%

Share of Medicare patients with each condition. A patient can have several.

Ryan Knake's patients across all payers

Dmand AI patient panel data covers Medicare, Medicaid and commercial patients.

Patient panel by age, all payers

Median age 70

Patient panel by sex, all payers

  • Women33%
  • Men67%

Sources: Dmand AI Patient Panel Data; and Medicare Physician & Other Practitioners - by Provider (CMS), 2024 data

Ryan D. Knake wrote 350 Medicare Part D claims in 2024

In 2024, Ryan Knake wrote 350 Medicare Part D claims for 153 patients. 93% of them were for generic drugs. CMS names the drug for 211 of them, across 8 drugs with 11 or more claims each, at $16,592 in total drug cost.

Part D claims, 2024350
Drugs named by CMS8
Total drug cost$16,592
Part D patients153

Ryan Knake's Part D claims by kind of drug, 2024

  • Generic324 claims93%
  • Brand-name26 claims7%

Ryan Knake's most prescribed drugs by claims, 2024

CMS names a drug when it has 11 or more claims. Share is of the claims for drugs CMS names.

Drug classes CMS tracks in Ryan Knake's Part D claims, 2024

  • Opioids11%37 of 350 claims

Share of all Part D claims for each drug class CMS reports on. Classes with no claims are left out.

See all prescribing by Ryan Knake

Sources: Medicare Part D Prescribers - by Provider and Drug (CMS), 2024 data, released May 6, 2026; and Medicare Part D Prescribers - by Provider (CMS), 2024 data

How Ryan D. Knake takes part in Medicare

Ryan Knake accepts Medicare assignment, so Medicare's approved amount is taken as full payment.

Accepts Medicare assignment
Yes

Source: Doctors and Clinicians National Downloadable File (CMS)

For MedTech and pharma teams

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Ryan D. Knake received $176 in industry payments from 2024 to 2025

CMS Open Payments shows 7 general payments to Ryan Knake from 6 drug and device companies from 2024 to 2025. Food and beverage make up the largest share, 100% of the total. Novocure Inc. paid the most, $58.

General payments to Ryan Knake by program year, 2024 to 2025

Companies that paid Ryan Knake the most, 2024 to 2025

Share is of all general payments to this clinician.

See all payments to Ryan Knake

Source: Open Payments (CMS), 2025 data, released July 7, 2026

Ryan D. Knake is board certified in certified physician assistant

  1. Board certified in certified physician assistantNational Commission on Certification of Physician Assistants (NCCPA)

Source: Dmand AI Professional Profile Data

Sources for Ryan D. Knake's profile data

Sources for the data on this page
Data on this pageSource
NPI, name, sex, specialty and licensesNPPES NPI Registry (CMS) (opens in a new tab)Dmand AI Professional Profile Data
Practice locations and phoneDmand AI Affiliation Data
Primary practice, affiliations and health systemDmand AI Affiliation DataDmand AI Org Hierarchy Data
Medicare services and procedure codesMedicare Physician & Other Practitioners - by Provider and Service (CMS) (opens in a new tab)
State medians for the same specialtyDmand AI Peer Benchmarks
Medicare patients and the all-payer patient panelDmand AI Patient Panel DataMedicare Physician & Other Practitioners - by Provider (CMS) (opens in a new tab)
Part D prescribingMedicare Part D Prescribers - by Provider and Drug (CMS) (opens in a new tab)Medicare Part D Prescribers - by Provider (CMS) (opens in a new tab)
MIPS scores, telehealth, assignment and procedure percentilesDoctors and Clinicians National Downloadable File (CMS) (opens in a new tab)
Industry paymentsOpen Payments (CMS) (opens in a new tab)
Training, board certification and membershipsDmand AI Professional Profile Data
EHR at each practice siteDmand AI Technology Install Data
Similar physiciansDmand AI Affiliation Data

Data last refreshed October 2026Report an inaccuracyRemove my information

FAQ

Frequently asked questions about Ryan D. Knake

Spotted something out of date? Email hello@dmand.ai and we will check the record. Contact details live in the free trial.

What is Ryan D. Knake's NPI number?

Ryan D. Knake's NPI number is 1063805745. It was assigned on March 5, 2015, and it is active in the NPI Registry.

What does Ryan D. Knake specialize in?

Ryan D. Knake is a physician assistant in Cape Coral, Florida. The primary specialty in the NPI Registry is Physician Assistant (taxonomy code 363A00000X).

Where does Ryan D. Knake practice?

Ryan Knake practices at 636 Del Prado Blvd, Cape Coral, FL 33990. Ryan Knake's primary practice is Cape Coral Hospital in Cape Coral, Florida, part of Lee Health System. Dmand AI also links Ryan Knake to 1 hospital and 1 group practice or clinic.

What is Ryan D. Knake's office phone number?

The practice phone on file for Ryan Knake is (239) 424-2000.

What is Ryan D. Knake's medical license number?

Ryan Knake holds Florida license PA9108558.

Which hospitals is Ryan D. Knake affiliated with?

Ryan Knake practices at Cape Coral Hospital in Cape Coral, Florida. Ryan Knake is also affiliated with Lee Memorial Hospital. Dmand AI links Ryan Knake to 1 more hospital.

What medical group is Ryan D. Knake part of?

Ryan Knake is linked to GenesisCare.

Does Ryan D. Knake accept Medicare?

Yes. CMS data shows Ryan Knake billed Medicare for 1,680 services in 2024, and Ryan Knake accepts Medicare assignment.

How many Medicare patients does Ryan D. Knake see?

CMS counts 92 Medicare patients who saw Ryan Knake in 2024, with an average age of 76.

Is Ryan D. Knake board certified?

Yes. Ryan Knake is board certified in certified physician assistant by the National Commission on Certification of Physician Assistants (NCCPA).

Show 4 more questionsShow fewer questions

What services does Ryan D. Knake bill to Medicare?

In 2024, Ryan Knake's most billed Medicare services were hospital inpatient care (99231), hospital inpatient care (99232) and hospital inpatient care (99222).

What drugs does Ryan D. Knake prescribe most?

In 2024 Medicare Part D data, Ryan Knake's most prescribed drugs by claims were Tamsulosin HCl, Prednisone and Abiraterone Acetate.

Has Ryan D. Knake received payments from drug or device companies?

CMS Open Payments shows $176 in general payments to Ryan Knake from 6 companies from 2024 to 2025. The largest total came from Novocure Inc.

How long has Ryan D. Knake been practicing?

Ryan Knake graduated from medical school in 2015, 11 years ago.

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