Dr. William E. Karnes Jr., MD

  • Orange, CA
  • Gastroenterologist
NPI1881652998PAC ID5294793501
Medicare services, 2024
827
Medicare patients, 2024
580
Part D claims, 2024
1,323
Publications
46
MIPS score, 2024
100
Practice address
101 City Drive South, Orange, CA 92868
Practice phone
Call (714) 456-7890
Professional email
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Personal email
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Mobile number
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Social profiles

Primary practice

UCI Health - Orange

Hospital · Orange, California

See all 4 affiliations

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Dr. William E. Karnes Jr. is a gastroenterologist in Orange, California

Dr. Karnes practices at UCI Health - Orange in Orange, California, part of UC Irvine.

Dr. Karnes' NPI, 1881652998, was assigned on May 1, 2006. Dr. Karnes graduated from University Of Minnesota Medical School in 1982. Dr. Karnes holds California license G57458.

NPI and contact details
Medicare PAC ID
5294793501
NPI enumeration date
May 1, 2006
NPI status
Active
Accepts Medicare assignment
Yes
Offers telehealth
Yes
Practice phone
(714) 456-7890
Professional email
Get email
Personal email
Get email
Mobile number
Get number
Sex
Male
Estimated age
70
Medical school graduation
1982

Sources: NPPES NPI Registry (CMS); Dmand AI Professional Profile Data; Dmand AI Affiliation Data; and Doctors and Clinicians National Downloadable File (CMS)

Dr. William E. Karnes Jr. practices at UCI Health - Orange in Orange, California

Dr. Karnes' primary practice is UCI Health - Orange, at 101 City Drive South, Orange, CA 92868 in Orange County. The practice phone is (714) 456-7890.

  • UCI Health - Orange
    101 City Drive South, Orange, CA 92868 · Orange CountyPhone(714) 456-7890

Source: Dmand AI Affiliation Data

Dr. William E. Karnes Jr. is affiliated with 2 sites of care and 2 medical groups

Dr. Karnes' primary practice is UCI Health - Orange in Orange, California, part of UC Irvine. The medical group on file is UCI Health Physicians. Dmand AI also links Dr. Karnes to 1 more group practice or clinic and 1 medical group, each named with a free account.

See all 4 affiliations for Dr. Karnes

Sources: Dmand AI Affiliation Data; and Dmand AI Org Hierarchy Data

Dmand AI tracks the EHR system at Dr. William E. Karnes Jr.'s practice

Dmand AI tracks the electronic health record (EHR) system at each site where Dr. Karnes practices, 2 sites in all. Vendor and product names are available with a free account.

EHR by site
SiteEHR vendor and product
UCI Health - OrangeAvailable with a free account
+1 more site and 1 medical groupAvailable with a free account

Source: Dmand AI Technology Install Data

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Dr. William E. Karnes Jr. is one of 1,977 gastroenterologists in California

Gastroenterology is Dr. Karnes' primary specialty in the NPI Registry, under taxonomy code 207RG0100X. Dr. Karnes is board certified in gastroenterology by the American Board of Internal Medicine. Dmand AI has Dr. Karnes' licenses on file in 2 states: California and Minnesota.

Specialties and state licenses

  • Gastroenterology, CaliforniaPrimaryLicense G57458 · 1986 to 2026 · taxonomy 207RG0100X
  • Minnesota license1984 to 2004

Clinical focus

Dmand AI lists acid reflux, anxiety, chronic anemia, chronic indigestion, fibromyalgia and chronic pain, gastroduodenitis, gastroenteritis and gastrointestinal bleeding among the conditions Dr. Karnes treats.

Gastroenterologists near Dr. Karnes

Counts of gastroenterologists with a Dmand AI profile, by place and practice. Each opens the list.

Sources: NPPES NPI Registry (CMS); Dmand AI Professional Profile Data; and Dmand AI Peer Benchmarks

Dr. William E. Karnes Jr. billed Medicare for 827 services in 2024

CMS data shows 827 Medicare services from Dr. Karnes across 17 procedure codes in 2024, for 580 Medicare patients. Medicare paid $105,529 for them.

Medicare services, 2024827
Medicare patients580
Paid by Medicare$105,529
Procedure codes17

Dr. Karnes' Medicare services by type, 2023 to 2024

  • 2023
  • 2024
Surgery
2023: 4342024: 4008%
Office and hospital visits
2023: 4092024: 32221%
Other services
2023: 592024: 602%
Tests and treatments
2023: 602024: 4525%

Where Dr. Karnes' Medicare services took place, 2024

  • In an office22327%
  • In a facility60473%

Dr. Karnes compared with the California median for gastroenterologists, 2024

  • Dr. Karnes
  • California median
Medicare services
827vs 58641% above
Medicare patients
580vs 30292% above
Part D claims
1,151vs 3803.0 times

Medians across 1,875 gastroenterologists in California with Dmand AI profiles that report each measure.

Dr. Karnes' most billed Medicare procedure codes, 2024

CMS publishes codes billed for 11 or more Medicare patients. Each label is the code family; CPT descriptions are licensed by the AMA.

See all procedures by Dr. Karnes

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Sources: Medicare Physician & Other Practitioners - by Provider and Service (CMS), 2024 data; and Dmand AI Peer Benchmarks

Dr. William E. Karnes Jr. treated 580 Medicare patients in 2024, average age 71

CMS counts 580 Medicare patients who saw Dr. Karnes in 2024. The largest group is 65 to 74, with 288 patients. 75% of them have high cholesterol, and 68% have high blood pressure. 33% are also on Medicaid. Their average risk score is 1.79, where 1.00 is the Medicare average, so they are sicker than most Medicare patients.

Across all payers, Dmand AI patient panel data puts Dr. Karnes' median patient age at 58, with 56% women.

Medicare patients, 2024580
Average age71
Average risk score1.79
Also on Medicaid33%

Dr. Karnes' Medicare patients by age, 2024

Dr. Karnes' Medicare patients by sex, 2024

  • Women31855%
  • Men26245%

Chronic conditions among Dr. Karnes' Medicare patients, 2024

  1. High cholesterol75%
  2. High blood pressure68%
  3. Arthritis51%
  4. Diabetes34%
  5. Ischemic heart disease30%
  6. Mood disorders29%
  7. Osteoporosis29%
  8. Anxiety27%

Share of Medicare patients with each condition. A patient can have several.

Dr. Karnes' patients across all payers

Dmand AI patient panel data covers Medicare, Medicaid and commercial patients.

Patient panel by age, all payers

Median age 58

Patient panel by sex, all payers

  • Women56%
  • Men43%

Sources: Dmand AI Patient Panel Data; and Medicare Physician & Other Practitioners - by Provider (CMS), 2024 data

Dr. William E. Karnes Jr. wrote 1,323 Medicare Part D claims in 2024

In 2024, Dr. Karnes wrote 1,323 Medicare Part D claims for 553 patients. 78% of them were for generic drugs. CMS names the drug for 1,151 of them, across 19 drugs with 11 or more claims each, at $246,371 in total drug cost. In 2023, CMS named 1,153 claims across 19 drugs.

Part D claims, 20241,323
Drugs named by CMS19
Total drug cost$246,371
Part D patients553

Dr. Karnes' Part D claims by kind of drug, 2024

  • Generic1,034 claims78%
  • Brand-name and other289 claims22%

Dr. Karnes' most prescribed drugs by claims, 2024

CMS names a drug when it has 11 or more claims. Share is of the claims for drugs CMS names.

Drug classes CMS tracks in Dr. Karnes' Part D claims, 2024

  • Antibiotics4%47 of 1,323 claims

Share of all Part D claims for each drug class CMS reports on. Classes with no claims are left out.

Part D claims for drugs CMS names, 2023 to 2024

  • 2023
  • 2024
Claims for drugs CMS names
2023: 1,1532024: 1,151No change

Drugs named by CMS: 19 in 2024, 19 in 2023.

See all prescribing by Dr. Karnes

Sources: Medicare Part D Prescribers - by Provider and Drug (CMS), 2024 data, released May 6, 2026; and Medicare Part D Prescribers - by Provider (CMS), 2024 data

Dr. William E. Karnes Jr. scored 100 out of 100 in Medicare's MIPS program for 2024

CMS publishes a Merit-based Incentive Payment System (MIPS) score of 100 out of 100 for Dr. Karnes for performance year 2024, reported through an alternative payment model (APM). Dr. Karnes accepts Medicare assignment, so Medicare's approved amount is taken as full payment. CMS lists Dr. Karnes as offering telehealth. CMS counts 260 procedures of colonoscopy by Dr. Karnes, more than 96% of the clinicians it reports for that procedure.

Accepts Medicare assignment
Yes
Offers telehealth
Yes

Dr. Karnes' MIPS scores, performance year 2024

  • 100of 100Final score
  • 83.7of 100Quality
  • 100of 100Promoting Interoperability
  • 40of 100Improvement Activities

Each score is out of 100. The final score weighs the categories CMS scored for this clinician.

Where Dr. Karnes ranks in Medicare procedure volume

Colonoscopy
96th percentile260 procedures
Upper gastrointestinal (GI) endoscopy for acid reflux
84th percentile142 procedures

CMS ranks each clinician against every clinician it reports for the same procedure category.

Sources: Doctors and Clinicians National Downloadable File (CMS); Clinician Public Reporting: Overall MIPS Performance (CMS), 2024 data, released September 10, 2026; and Doctors and Clinicians Utilization Data (CMS)

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Dr. William E. Karnes Jr. has 46 publications on record

Dmand AI links 46 papers to Dr. Karnes, published from 2013 to 2023. 2020 was the busiest year, with 3. The most frequent topics are Colonoscopy, Adenoma and Colorectal Neoplasms. Dr. Karnes has published most often in Gastroenterology. Dr. Karnes' most frequent co-authors are Jason Buddika Samarasena, MD, Alexander Philip Abadir, MD and Tyler M. Berzin, MD.

Papers46
Years published2013 to 2023

Dr. Karnes' papers by year, 2013 to 2023

Topics Dr. Karnes writes about most

  • Colonoscopy
  • Adenoma
  • Colorectal Neoplasms
  • Observer Variation
  • Adenomatous Polyposis Coli
  • Antineoplastic Agents
  • Artificial Intelligence
  • Cathartics

Dr. Karnes' most frequent co-authors

Recent publications by Dr. Karnes

See all 46 publications and co-authors

See who Dr. Karnes researches with

Physician Network Discovery turns co-authorship, shared hospitals and shared groups into a map of who Dr. Karnes works with, so you can find a warm path to the right gastroenterologists.

How network discovery works

Sources: PubMed (National Library of Medicine); and Dmand AI Research Linkage

Dr. William E. Karnes Jr. received $20,686 in industry payments from 2016 to 2025

CMS Open Payments shows 36 general payments to Dr. Karnes from 8 drug and device companies from 2016 to 2025. Consulting fees make up the largest share, 84% of the total. Medivators Inc. paid the most, $18,749.

General payments to Dr. Karnes by program year, 2016 to 2025

General payments to Dr. Karnes by kind, 2016 to 2025

$20.7Kin total
  • Consulting fees$17,27684%
  • Food and beverage$2,32611%
  • Travel and lodging$1,0845%

Companies that paid Dr. Karnes the most, 2016 to 2025

Share is of all general payments to this clinician.

See all payments to Dr. Karnes

Source: Open Payments (CMS), 2025 data, released July 7, 2026

Dr. William E. Karnes Jr. has 7 awards and honors on record

Dmand AI lists 7 awards for Dr. Karnes, most recently AGA Fellow in 2011.

Awards and honors for Dr. Karnes

  1. 2011
    • AGA Fellow
  2. 2009
    • CMS Stage 1 2012
    • Fellow
  3. 2003
    • MHA PACE Star Award
  4. 1995
    • American Federation of Clinical Research Award
  5. 1994
    • Young Scholar Award
See all 7 awards

Source: Dmand AI Professional Profile Data

Dr. William E. Karnes Jr. graduated from University Of Minnesota Medical School

Dr. Karnes graduated from University Of Minnesota Medical School in 1982. Dr. Karnes is a member of AGA.

  1. Medical schoolUniversity Of Minnesota Medical School
  2. Board certified in gastroenterologyAmerican Board of Internal Medicine
  3. Board certified in internal medicineAmerican Board of Internal Medicine

Source: Dmand AI Professional Profile Data

Dr. William E. Karnes Jr. accepts plans from 13 insurance carriers

Dr. Karnes is in network with 13 carriers, including Aetna, Elevance and Blue Cross Blue Shield of Michigan. PPO plans come from the most carriers, 9. Check the plan with the practice before a visit.

  • Aetna
  • Elevance
  • Blue Cross Blue Shield of Michigan
  • United Healthcare
  • HCSC
  • Blue Cross Blue Shield of Massachusetts
  • Regence Health Plans
  • Alliant Health Plans
  • +5 more carriersWith a free account

Plan types Dr. Karnes accepts, by number of carriers

  1. PPO9
  2. Medicare8
  3. HMO6
  4. EPO4
  5. POS4

Source: Dmand AI Insurance Network Data

Sources for Dr. William E. Karnes Jr.'s profile data

Sources for the data on this page
Data on this pageSource
NPI, name, sex, specialty and licensesNPPES NPI Registry (CMS) (opens in a new tab)Dmand AI Professional Profile Data
Practice locations and phoneDmand AI Affiliation Data
Primary practice, affiliations and health systemDmand AI Affiliation DataDmand AI Org Hierarchy Data
Medicare services and procedure codesMedicare Physician & Other Practitioners - by Provider and Service (CMS) (opens in a new tab)
State medians for the same specialtyDmand AI Peer Benchmarks
Medicare patients and the all-payer patient panelDmand AI Patient Panel DataMedicare Physician & Other Practitioners - by Provider (CMS) (opens in a new tab)
Part D prescribingMedicare Part D Prescribers - by Provider and Drug (CMS) (opens in a new tab)Medicare Part D Prescribers - by Provider (CMS) (opens in a new tab)
MIPS scores, telehealth, assignment and procedure percentilesDoctors and Clinicians National Downloadable File (CMS) (opens in a new tab)Clinician Public Reporting: Overall MIPS Performance (CMS) (opens in a new tab)Doctors and Clinicians Utilization Data (CMS) (opens in a new tab)
Publications, topics and co-authorsPubMed (National Library of Medicine) (opens in a new tab)Dmand AI Research Linkage
Industry paymentsOpen Payments (CMS) (opens in a new tab)
Awards and committee rolesDmand AI Professional Profile Data
Training, board certification and membershipsDmand AI Professional Profile Data
Insurance carriers and plan typesDmand AI Insurance Network Data
EHR at each practice siteDmand AI Technology Install Data
Similar physiciansDmand AI Affiliation Data

Data last refreshed October 2026Report an inaccuracyRemove my information

FAQ

Frequently asked questions about Dr. William E. Karnes Jr.

Spotted something out of date? Email hello@dmand.ai and we will check the record. Contact details live in the free trial.

What is Dr. William E. Karnes Jr.'s NPI number?

Dr. William E. Karnes Jr.'s NPI number is 1881652998. It was assigned on May 1, 2006, and it is active in the NPI Registry.

What kind of doctor is Dr. William E. Karnes Jr.?

Dr. William E. Karnes Jr. is a gastroenterologist in Orange, California. The primary specialty in the NPI Registry is Gastroenterology Physician (taxonomy code 207RG0100X).

Where does Dr. William E. Karnes Jr. practice?

Dr. Karnes practices at 101 City Drive South, Orange, CA 92868. Dr. Karnes' primary practice is UCI Health - Orange in Orange, California, part of UC Irvine. Dmand AI also links Dr. Karnes to 1 group practice or clinic and 1 medical group.

What is Dr. William E. Karnes Jr.'s office phone number?

The practice phone on file for Dr. Karnes is (714) 456-7890.

What is Dr. William E. Karnes Jr.'s medical license number?

Dr. Karnes holds California license G57458, one of the licenses on file in 2 states.

Which states has Dr. William E. Karnes Jr. been licensed in?

Dmand AI has state licenses on file for Dr. Karnes in California (1986 to 2026) and Minnesota (1984 to 2004).

Which hospitals is Dr. William E. Karnes Jr. affiliated with?

Dr. Karnes practices at UCI Health - Orange in Orange, California.

What medical group is Dr. William E. Karnes Jr. part of?

Dr. Karnes is linked to UCI Health Physicians. Dmand AI links Dr. Karnes to 1 more medical group.

Does Dr. William E. Karnes Jr. accept Medicare?

Yes. CMS data shows Dr. Karnes billed Medicare for 827 services in 2024, and Dr. Karnes accepts Medicare assignment.

Does Dr. William E. Karnes Jr. offer telehealth?

Yes. The CMS Doctors and Clinicians file lists Dr. Karnes as offering telehealth services.

Show 11 more questionsShow fewer questions

What is Dr. William E. Karnes Jr.'s MIPS score?

Dr. Karnes' MIPS final score for performance year 2024 is 100 out of 100, reported through an alternative payment model (APM).

How many Medicare patients does Dr. William E. Karnes Jr. see?

CMS counts 580 Medicare patients who saw Dr. Karnes in 2024, with an average age of 71.

Is Dr. William E. Karnes Jr. board certified?

Yes. Dr. Karnes is board certified in gastroenterology by the American Board of Internal Medicine.

What services does Dr. William E. Karnes Jr. bill to Medicare?

In 2024, Dr. Karnes' most billed Medicare services were surgery: digestive system (45385), office visit, established patient (99214) and surgery: digestive system (43239).

Where did Dr. William E. Karnes Jr. go to medical school?

Dr. Karnes graduated from University Of Minnesota Medical School in 1982.

What drugs does Dr. William E. Karnes Jr. prescribe most?

In 2024 Medicare Part D data, Dr. Karnes' most prescribed drugs by claims were Peg 3350-Electrolyte, Omeprazole and Pantoprazole Sodium.

Has Dr. William E. Karnes Jr. received payments from drug or device companies?

CMS Open Payments shows $20,686 in general payments to Dr. Karnes from 8 companies from 2016 to 2025. The largest total came from Medivators Inc.

How long has Dr. William E. Karnes Jr. been practicing?

Dr. Karnes graduated from medical school in 1982, 44 years ago.

Does Dr. William E. Karnes Jr. do research?

Dmand AI links 46 publications to Dr. Karnes, published from 2013 to 2023.

Who does Dr. William E. Karnes Jr. publish with?

Dr. Karnes' most frequent co-authors are Jason Buddika Samarasena, MD (4 shared papers), Alexander Philip Abadir, MD (2 shared papers) and Tyler M. Berzin, MD (2 shared papers).

What insurance does Dr. William E. Karnes Jr. accept?

Dr. Karnes is in network with 13 carriers, including Aetna, Elevance and Blue Cross Blue Shield of Michigan. PPO plans come from the most carriers, 9. Check the plan with the practice before a visit.

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