Lead Sponsor: Beijing Friendship Hospital

Collaborators: Fudan University, Nanfang Hospital, Southern Medical University, Peking University People's Hospital, Affiliated Hospital of Yanbian University, Shanghai Public Health Clinical Center, Beijing YouAn Hospital, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine

Intervention / Treatment: DRUG: Entecavir

Lead Sponsor: Beijing Friendship Hospital

Collaborators: Beijing Tiantan Hospital, Tongji Hospital, Peking Union Medical College Hospital, Nanfang Hospital, Southern Medical University, Sir Run Run Shaw Hospital, Shanghai Zhongshan Hospital, Peking University First Hospital, The First Affiliated Hospital of Shanxi Medical University, Tang-Du Hospital, RenJi Hospital, Peking University, Peking University People's Hospital, Shanghai Public Health Clinical Center, Beijing YouAn Hospital, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Beijing 302 Hospital, Beijing Ditan Hospital, Huashan Hospital, Fifth Hospital of Shijiazhuang City, Logistics University of Chinese People's Armed Police Forces, The Affiliated Hospital of Yanbian University

Intervention / Treatment: DRUG: Peg-IFN, DRUG: entecavir

Lead Sponsor: Beijing Friendship Hospital

Collaborators: Beijing Tiantan Hospital, Fudan University, Tongji Hospital, Peking Union Medical College Hospital, Nanfang Hospital, Southern Medical University, Sir Run Run Shaw Hospital, Shanghai Zhongshan Hospital, Peking University First Hospital, The First Affiliated Hospital of Shanxi Medical University, Tang-Du Hospital, RenJi Hospital, Peking University, Peking University People's Hospital, Shanghai Public Health Clinical Center, Beijing YouAn Hospital, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Beijing 302 Hospital, Beijing Ditan Hospital, Huashan Hospital, Fifth Hospital of Shijiazhuang City, Logistics University of Chinese People's Armed Police Forces, The Affiliated Hospital of Yanbian University

Intervention / Treatment: DRUG: entecavir, DRUG: Thymosin-α