Lead Sponsor: Ferring Pharmaceuticals

Collaborators: Duke Clinical Research Institute, Memorial Sloan Kettering Cancer Center

Intervention / Treatment: DRUG: Degarelix, DRUG: Leuprolide

Lead Sponsor: Duke University

Collaborators: Patient-Centered Outcomes Research Institute, Medidata Solutions, Chicago Area Patient-Centered Outcomes Research Network (CAPriCORN), Greater Plains Collaborative Clinical Data Research Network, Mid-South Clinical Data Research Network, Research Action for Health Network (REACHnet), The Patient-Oriented Scalable National Network for Effectiveness Research, PaTH Clinical Data Research Network, New York City Clinical Data Research Network, The Health eHeart Alliance, OneFlorida Clinical Data Research Network, HealthCore-Anthem Research Network, Humana Inc., The Patient-Centered Network of Learning Health Systems

Intervention / Treatment: DRUG: aspirin

Lead Sponsor: Regeneron Pharmaceuticals

Collaborators: Sanofi, Aimmune Therapeutics, Inc.

Intervention / Treatment: DRUG: Dupilumab, DRUG: AR101, DRUG: Placebo matching dupilumab