Lead Sponsor: Duke University

Collaborators: National Human Genome Research Institute (NHGRI), Vanderbilt University Medical Center, University of Florida, Icahn School of Medicine at Mount Sinai, Indiana University School of Medicine

Intervention / Treatment: OTHER: Timing of return of results

Lead Sponsor: National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Collaborators: University of Pennsylvania, Yale University, Massachusetts General Hospital, University of Pittsburgh, Vanderbilt University Medical Center, University of Washington, West Virginia University, New York University, University of New Mexico, University of Illinois at Chicago, Dallas VA Medical Center, Durham VA Health Care System, VA New York Harbor Healthcare System, Hennepin Health Care, Rogosin Institute, VA Portland Healthcare System, West Haven VA Medical Center

Intervention / Treatment: DRUG: Buprenorphine, BEHAVIORAL: Pain Coping Skills Training (PCST)