Lead Sponsor: University of Melbourne

Collaborators: King's College London, UMC Utrecht, Sunnybrook Health Sciences Centre, University College, London, Berry Consultants, Rambam Health Care Campus, Radboud University Medical Center, McGill University Health Centre/Research Institute of the McGill University Health Centre, Menzies School of Health Research, Aotearoa Clinical Trials, Queensland University of Technology, Tan Tock Seng Hospital, Telethon Kids Institute, The Peter Doherty Institute for Infection and Immunity, The University of Queensland, Houston Medical Research Institute

Intervention / Treatment: DRUG: Cefazolin, DRUG: Vancomycin, DRUG: Clindamycin, DRUG: Penicillin, OTHER: Effectiveness of early switch to oral antibiotics, RADIATION: Whole body FDG PET/CT Imaging

Lead Sponsor: Abbott Medical Devices

Intervention / Treatment: DEVICE: Dorsal root ganglion stimulation (DRG), DEVICE: Spinal cord stimulation (SCS)