Lead Sponsor: Rhythm Pharmaceuticals, Inc.

Lead Sponsor: Children's Hospital Medical Center, Cincinnati

Collaborators: Children's Hospital Los Angeles, Mayo Clinic, University of California, Los Angeles, University of Alabama at Birmingham, The Cleveland Clinic, Duke University, UCSF Benioff Children's Hospital Oakland, University of Florida, University of New Mexico, University of Kentucky, Milton S. Hershey Medical Center, Children's Mercy Hospital Kansas City, Arnold Palmer Hospital for Children, Connecticut Children's Medical Center, Ann & Robert H Lurie Children's Hospital of Chicago, Seattle Children's Hospital, St. Louis Children's Hospital, Helen DeVos Children's Hospital, National Association of Children's Hospitals and Related Institutions (NACHRI), University of Illinois College of Medicine at Peoria, The Children's Hospital of San Antonio, Arkansas Children's Hospital Research Institute, Florida Hospital for Children, University of Oklahoma, MaineHealth, Eastern Maine Medical Center, Gramercy Pediatrics, Dartmouth-Hitchcock Medical Center, University of Tulsa, Northern Arizona Healthcare