Lead Sponsor: University of Alabama at Birmingham

Collaborators: University of California, San Diego, National Heart, Lung, and Blood Institute (NHLBI), University of Pennsylvania, San Francisco General Hospital, Emory University, University of California, San Francisco, Vanderbilt University, Yale University, Medical University of South Carolina, Northwestern University, Stanford University, Ochsner Health System, Indiana University, University of Iowa, Columbia University, The Cleveland Clinic, University of Utah, University of Arkansas, Medical College of Wisconsin, Oregon Health and Science University, University of Pittsburgh, Duke University, University of Colorado, Denver, Wake Forest University Health Sciences, Washington University School of Medicine, Intermountain Health Care, Inc., Johns Hopkins University, The University of Texas Health Science Center, Houston, Baylor College of Medicine, Temple University, University of Oklahoma, Winthrop University Hospital, Geisinger Clinic, Weill Medical College of Cornell University, Ohio State University, University of Texas Southwestern Medical Center, University of Kansas Medical Center, Women and Infants Hospital of Rhode Island, St. Luke's Hospital and Health Network, Pennsylvania, Arrowhead Regional Medical Center, Lehigh Valley Hospital, University of South Alabama, University of North Carolina, Chapel Hill, Christiana Care Health Services, Beaumont Hospital, The University of Texas Medical Branch, Galveston, Tulane University, University of Tennessee, Saint Peters University Hospital, Latter Day Saints Hospital, Denver Health and Hospital Authority, Drexel University College of Medicine, Virtua Medical Group, WakeMed Health and Hospitals, Rutgers, The State University of New Jersey, McKay-Dee Hospital, New York Hospital Queens, Lyndon B Johnson General Hospital, Duke Regional Hospital, Utah Valley Regional Medical Center, Case Western/Metro Health, Meriter Foundation, Gundersen Health System, New Jersey Medical School, TriHealth Inc., Miami Valley Hospital

Intervention / Treatment: DRUG: Anti-hypertensive therapy, OTHER: No anti-hypertensive therapy (unless BP is severe)