Lead Sponsor: Biogen

Intervention / Treatment: DRUG: Placebo Oral Capsule, DRUG: Bardoxolone Methyl

Lead Sponsor: GlaxoSmithKline

Intervention / Treatment: DRUG: Placebo, DRUG: Darbepoetin alfa, DRUG: Iron Therapy, DRUG: Daprodustat

Lead Sponsor: Sanofi

Intervention / Treatment: DRUG: Background Therapy, DRUG: Insulin glargine, 300 U/ml, DRUG: Insulin glargine, 100 U/ml, DRUG: Insulin detemir