Lead Sponsor: Jaeb Center for Health Research

Intervention / Treatment: DIAGNOSTIC_TEST: Spirometry, OTHER: Food Frequency Questionnaire, DEVICE: Continuous glucose monitoring (CGM), DIAGNOSTIC_TEST: BMI and lean mass index from DXA, DIAGNOSTIC_TEST: Anthropometric Measurements, DIAGNOSTIC_TEST: Hand-grip strength, DIAGNOSTIC_TEST: Six-minute walk Test, DIAGNOSTIC_TEST: Sit-to-Stand Test, DIAGNOSTIC_TEST: Short physical performance battery (SPPB), DIAGNOSTIC_TEST: BIA Sub-study, DIAGNOSTIC_TEST: Accelerometry to assess physical activity, OTHER: Gastrointestinal (GI) and nutrition questionnaires:, OTHER: Psychosocial questionnaire: PHQ-8, OTHER: Psychosocial questionnaire: GAD-7, OTHER: Psychosocial questionnaire: The Treatment Self-Regulation Questionnaire (TSRQ), OTHER: Psychosocial questionnaire: CF Fatalism Scale, OTHER: Psychosocial questionnaire: Body Esteem Scale for Adolescents and Adults (BESAA), OTHER: 12-month Questionnaire, OTHER: Oral glucose tolerance testing (OGTT), DIAGNOSTIC_TEST: Chest CT scans (When available within the past 6 months in medical records), DIAGNOSTIC_TEST: Hologic Dual X-Ray Absorptiometry (DXA), DIAGNOSTIC_TEST: Ultrasound Sub-study of assessment of appendage muscles using ultrasound, DIAGNOSTIC_TEST: Psychosocial questionnaire: Hunger Vital Sign questionnaire, OTHER: Respiratory symptom questionnaire: CRISS, OTHER: Psychosocial questionnaire: Additional Health Questionnaire, OTHER: CF Management Questionnaire

Lead Sponsor: Boston Children's Hospital

Collaborators: Johns Hopkins University

Intervention / Treatment: BEHAVIORAL: Qualitative Interview

Lead Sponsor: Georgia Institute of Technology

Collaborators: National Institute on Aging (NIA)

Intervention / Treatment: DEVICE: Ankle Exoskeleton Assistance