Lead Sponsor: University of California, Davis

Collaborators: Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)

Intervention / Treatment: DRUG: 0.9% saline Intravenous fluid, DRUG: 0.45% saline replacement fluid, DRUG: 0.9% saline replacement fluid, DRUG: 0.45% saline intravenous fluid

Lead Sponsor: University of California, Davis

Collaborators: National Institute of Neurological Disorders and Stroke (NINDS)

Intervention / Treatment: OTHER: intravenous fluid treatment